Endogenous lateral electric fields around bovine corneal lesions are necessary for and can enhance normal rates of wound healing

Wound Repair and Regeneration

Volumn 6, Issue 6, 1998, Pages 531-542

  Sta Iglesia, Drina D ^a   Vanable Jr , Joseph W ^b  

^a GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMILORIDE; BENZAMIL; DRUG DERIVATIVE; HANKS BALANCED SALT SOLUTION; ISOTONIC SOLUTION; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL; ARTICLE; CATTLE; CELL MOTION; CORNEA; DRUG EFFECT; ELECTRICITY; ELECTROSTIMULATION THERAPY; INJURY; METHODOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; WOUND HEALING;

AMILORIDE; ANIMALS; CATTLE; CELL MOVEMENT; CORNEA; ELECTRIC STIMULATION THERAPY; ELECTRICITY; ISOTONIC SOLUTIONS; SODIUM CHANNEL BLOCKERS; WOUND HEALING;

EID: 0032199518     PISSN: 10671927     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-475X.1998.60606.x     Document Type: Article

References (34)

1. Robinson KR. The responses of cells to electrical fields: a review. J Cell Biol 1985;101:2023-7.
2. Nuccitelli R. Physiological electric fields can influence cell motility, growth, and polarity. In: Miller K, editor. Advances in cell biology, Vol. 2. Greenwich: JAI Press, 1988:213-34.
3. Rajnicek AM, Stump RF, Robinson KR. An endogenous sodium current may mediate wound healing in Xenopus neurulae. Dev Biol 1988;128:290-9.
4. Rhodes LR, Turek JJ, Cragoe, EJ Jr., Vanable JW Jr. Wound currents and wound healing in the newt, Notophthalmus viridescens. Roux's Arch Dev Biol 1990;198:355-62.
5. Chiang M, Cragoe EJ Jr, Vanable JW Jr. Electrical fields in the vicinity of small wounds in Notophthalmus viridescens skin. Biol Bull 1989;176 Suppl :179-83.
6. Chiang M, Cragoe EJ Jr, Vanable JW Jr. Intrinsic electric fields promote epithelization of wounds in the newt, Notophthalmus viridescens. Dev Biol 1991;146:377-85.
7. Sta. Iglesia DD, Cragoe EJ Jr, Vanable JW Jr. Electric field strength and epithelization in the newt (Notophthalmus viridescens). J Exp Zool 1996;274:56-62.
8. Chiang M, Robinson KR, Vanable JW Jr. Electrical fields in the vicinity of epithelial wounds in the isolated bovine eye. Exp Eye Res 1992; 54:999-1003.
9. Vanable JW Jr. Integumentary potentials and wound healing. In Borgens RB, Robinson KR, Vanable JW Jr, McGinnis ME, editors. Electric fields in vertebrate repair. New York, Wiley-Liss, 1989:171-224.
10. Kloth LC, Feedar JA. Electrical stimulation in tissue repair. In: Kloth LC, McCulloch JM, Feedar JA, editors. Wound healing: alternatives in management. Philadelphia: FA Davis Company. 1990:221-56.
11. Weiss DS, Kirsner R, Eaglstein WH. Electrical stimulation and wound healing. Arch Dermatol 1990;126:222-5.
12. McGinnis ME. The nature and effects of electricity in bone. In Borgens RB, Robinson KR, Vanable JW Jr, and McGinnis ME, editors. Electric fields in vertebrate repair. New York, Wiley-Liss, 1989;225-84.
13. Assimacopoulos D. Low intensity negative electric current in the treatment of ulcers of the leg due to chronic venous insufficiency. Am J Surg 1968;115:683-7.
14. Assimacopoulos D. Wound healing promotion by the use of negative electric current. Am Surg 1968;35:423-31.
15. Alvarez OM, Mertz PM, Smerbeck RV, Eaglstein WH. The healing of superficial skin wounds is stimulated by external electric current. Invest Dermatol 1983;81:1144-8.
16. Wolcott LE, Wheeler PC, Hardwicke HM, Rowley BA. Accelerated healing of skin ulcers by electrotherapy: preliminary clinical results. South Med J 1969;62:795-801.
17. Carley PJ, Wainapel SF. Electrotherapy for acceleration of wound healing: low intensity direct current. Arch Phys Med Rehabil 1985;66:443-6.
18. Kloth LC, Feedar JA. Acceleration of wound healing with high voltage, monophasic, pulsed current. Phys Ther 1988;68:503-8.
19. Mertz PM, Davis SC, Cazzaniga AL, Cheng K, Reich JD, Eaglstein WH. Electrical stimulation: acceleration of soft tissue repair by varying the polarity. Wounds 1993;5:153-9.
20. Cragoe EJ, Woltersdorf OW Jr, Bicking JB, Kwong SF, Jones JH. Pyrazine diuretics. II. N-amidino-3-amino-5-substituted-6-halopyrazinecarboxamides. J Med Chem 1967;10:66-75.
21. Haik BG, Zimny ML. Scanning electron microscopy of corneal wound healing in the rabbit. Invest Ophthalmol Vis Sci 1977;16:787-96.
22. Nishimura KY, Isseroff R, Nuccitelli R. Human keratinocytes migrate to the negative pole in direct current electric fields comparable to those measured in mammalian wounds. J Cell Sci 1996;109:199-207.
23. Cooper MS, Schliwa M. Electrical and ionic control of tissue cell locomotion in DC electric fields. J Neurosci Res 1985;13:223-44.
24. Ferrier J, Ross SM, Kanehisa J, Aubin JE. Osteoclasts and osteoblasts migrate in opposite directions in response to a constant electrical field. J Cell Physiol 1986;129:283-8.
25. Zhao M, Aguis-Fernandez A, Forrester VD, McCaig CD. Orientation and directed migration of cultured corneal epithelial cells in small electric fields are serum dependent. J Cell Sci 1996;109:1405-14.
26. Zhao M, Aguis-Fernandez A, Forrester VD, McCaig CD. Directed migration of corneal epithelial sheets in physiological electric fields. Invest Ophthalmol Vis Sci. 1996;37:2548-58.
27. Gruler H, Nuccitelli R. Neural crest cell galvanotaxis: new data and a novel approach to the analysis of both galvanotaxis and chemotaxis. Cell Motil Cytoskel 1991;19:121-33.
28. Sheridan R, Isseroff R, Nuccitelli R. Imposition of a physiologic dc electric field alters the migratory response of human keratinocytcs on ECM molecules. J Invest Dermatol 1996;106:642-6.
29. Soong HK, Parkinson WC, Bafna S, Sulik G, Huang S. Movements of cultured corneal epithelial cells and stromal fibroblasts in electric fields. Invest Ophthalmol Vis Sci 1990;31:2278-82.
30. Stump RF, Robinson KR. Xenopus neural crest cell migration in an applied electric field. J Cell Biol 1983;971:1226-33.
31. Erickson CA, Nuccitelli R. Embryonic fibroblast motility and orientation can be influenced by physiological electric fields. J Exp Zool 1984;251:123-33.
32. Nakamura M, Nishida T, Ofuji K, Reid TW, Mannis MJ, Murphy CJ. Synergistic effect of substance P with epidermal growth factor on epithelial migration in rabbit cornea. Exp Eye Res 1987; 65:321-9.
33. Garcia-Hirschfeld J, Lopez-Briones LG, Belmonte C. Neurotrophic influences on corneal epithelial cells. Exp Eye Res 1994;59:597-605.
34. Jones MA, Marfurt CF. Sympathetic stimulation of corneal epithelial proliferation in wounded and nonwounded eyes. Invest Ophthalmol Vis Sci 1996; 37:2535-47.