Immunolocalization of cathepsin B in equine dyschondroplastic articular cartilage

Veterinary Journal

Volumn 156, Issue 3, 1998, Pages 193-201

  Hernandez Vidal, G ^a   Jeffcott, L B ^b   Davies, M E ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Articular cartilage; Cathepsin B; Chondrocyte; Dyschondroplasia; Horse; Osteochondrosis

Indexed keywords

CATHEPSIN B;

ANIMAL; ANIMAL DISEASE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CATTLE; CELL CULTURE; CROSS REACTION; ENZYMOLOGY; HORSE; HORSE DISEASE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; MOLECULAR WEIGHT; OSTEOCHONDRITIS; PATHOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; SHEEP; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CATHEPSIN B; CATTLE; CELLS, CULTURED; CHONDROCYTES; CROSS REACTIONS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HORSE DISEASES; HORSES; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; OSTEOCHONDRITIS; SHEEP;

EID: 0032198854     PISSN: 10900233     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1090-0233(98)80122-6     Document Type: Article

References (47)

1. ALI, S. Y. (1967). The presence of cathepsin B in cartilage. The Biochemical Journal 102, 10-11C.
2. ALI, S. Y. & BAYLISS, M. T. (1975). Enzymes involved in degradation of cartilage in osteoarthritis. Annals of the Rheumatic Diseases 34 (Suppl. 2), 65-6.
3. ASPDEN, R. M. (1994). Fibre reinforcing by collagen in cartilage and soft connective tissues. Proceedings of the Royal Society, London B 258, 195-200.
4. BAICI, A., HÔRLER, D., LANG, A., MERLIN, C. & KISSLING, R. (1995a). Cathepsin B in osteoarthritis: zonal variation of enzyme activity in human femoral head cartilage. Annals of the Rheumatic Diseases 54, 281-8.
5. BAICI, A., LANG, A., HÔRLER, D., KISSLING, R. & MERLIN, C. (1995b). Cathepsin B in osteoarthritis: cytochemical and histochemical analysis of human femoral head cartilage. Annals of the Rheumatic Diseases 54, 289-97.
6. BAYLISS, M. T. & ALI, S. Y. (1978). Studies on cathepsin B in human articular cartilage. The Biochemical Journal 171, 149-54.
7. 3 chain indicate a bridging role for chicken collagen VI in connective tissues. Biochemistry 29, 1245-54.
8. BURLEIGH, M. C., BARRETT, A. J. & LAZARUS, G. S. (1974). Cathepsin B1. A lysosomal enzyme that degrades native collagen. The Biochemical Journal 137, 387-98.
9. 1 form of human cathepsin B from sputum. The Biochemical Journal 254, 693-9.
10. BUTTLE, D. J., HANDLEY, C. J., ILIC, M. Z., SAKLATVALA, J., MURMA, M. & BARRETT, A. J. (1993) Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation. Arthritis and Rheumatism 36, 1709-17.
11. BUTTLE, D. J., BRAMWELL, H. & HOLLANDER, A. P. (1995). Proteolytic mechanisms of cartilage breakdown: a targel for arthritis therapy. Journal of Clinical Pathology: Molecular Pathology 48, M167-77.
12. DODGE, G. R. & POOLE, A. R. (1989). Immunohistochemical detection and immunochemical analysis of type II collagen degradation in human normal, rheumatoid, and osteoarthritic articular cartilage and in explants of bovine articular cartilage cultured with interleukin 1. Journal of Clinical Investigation 83, 647-61.
13. ESSER, R. E., ANGELO, R. A., MURPHY, M. D., WATTS, L. M., THORNBURG, L. P., PALMER, J. T., TALHOUK, J. W. & SMITH, R. E. (1994). Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis. Arthritis and Rheumatism 37, 236-47.
14. EVERIS, V., KORPER, W., NIEHOF, A., JANSEN, I. & BEERISEN, W. (1994). Type VI collagen is phagocytosed by fibroblasts and digested in the lysosomal apparatus: involvement of collagenase, serine proteinases and lysosomal enzymes. Matrix Biology 14, 665-76.
15. GABRIJELČIČ, D., ANNAN-PRATT, A., RODIC, B., ROZMAN, B., COTIC, V. & TURK, V. (1990). Determination of cathepsins B and H in sera and synovial fluids of patients with different joint diseases. Journal of Clinical Chemistry and Clinical Biochemistry 28, 149-53.
16. GOTO, T., TSUKUBA, T., KIYOSHIMA, Y., KATO, K., YAMAMOTO, K. & TANAKA, T. (1993). Immunohistochemical localization of cathepsin B, D and L in the rat osteoclast. Histochemistry 99, 411-4.
17. HENDERSON, B. & BLAKE, S. (1994) Connective tissue destruction in rheumatoid arthritis: therapeutic potential of selective metalloproteinase inhibitors. In: Immunopharmacology of Joints and Connective Tissue, eds, M. E. Davies & J. T. Dingle. pp. 199-223. London: Academic Press.
18. HENSON, F. M. D., DAVIES, M. E. & JEFFCOTT, L. B. (1997). Equine dyschondroplasia (osteochondrosis)-histological findings and type VI collagen localisation. The Veterinary Journal 154, 53-63.
19. HERNANDEZ-VIDAL, G., DAVIES, M. E. & JEFFCOTT, L. B. (1996). Localization of cathepsins B and D in equine articular cartilage. Pferdeheilkunde 12, 371-3.
20. HERNANDEZ-VIDAL, G., JEFFCOTT, L. B. & DAVIES, M. E. (1997). Cellular heterogeneity in cathepsin D distribution in equine articular cartilage. Equine Veterinary Journal 29, 267-273.
21. IYAMA, K., NINOMIYA, Y., OLSEN, B. R., LINSENMAYER, T. F., TRELSTAD, R. L. & HAYASHI, M. (1991). Spatiotemporal pattern of type X collagen gene expression and collagen deposition in embryonic chick vertebrae undergoing endochondral ossification. Anatomical Record 229, 462-72.
22. JEFFCOTT, L. B. (1993). Problems and pointers in equine osteochondrosis. Equine Veterinary Journal (Supplement) 16, 1-3.
23. KIRSCH, T. & VON DER MARK, K. (1991). Isolation of human type X collagen and immunolocalization in fetal human cartilage. European Journal of Biochemistry 196, 575-80.
24. KOMINAMI, E., UENO, T., MUNO, D. & KATUNUMA, N. (1991). The selective role of cathepsins B and D in the lysosomal degradation of endogenous and exogenous proteins. FEBS Letters 287, 189-92.
25. KUETTNER, K. E. (1992). Biochemistry of articular cartilage in health and disease. Clinical Biochemistry 25, 155-63.
26. LAEMMLI, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-5.
27. LEE, E. R., LAMPLUGH, L., SHEPARD, N. L. & MORT, J. S. (1995). The septoclast, a cathepsin B-rich cell involved in the resorption of growth plate cartilage. Journal of Histochemistry and Cytochemistry 43, 525-36.
28. LILLICH, J. D., BERTONE, A. L., MALEMUD, C. J., WEISBRODE, S. E., RUGGLES, A. J. & STEVENSON, S. (1997). Biochemical, histochemical, and immunohistochemical characterization of distal tibial osteochondrosis in horses. American Journal of Veterinary Research 58, 89-98.
29. MACIEWICZ, R. A., WOOTTON, S. F., ETHERINGTON, D. J. & DUANCE, V. C. (1991). Susceptibility of the cartilage collagens types II, IX and XI to the cysteine proteinases, cathepsins B and L. FEBS Letters 269, 189-92.
30. MANKIN, H. J. & LIPPIELLO, L. (1970). Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. Journal of Bone and Joint Surgery 52A, 424-34.
31. MARTEL-PELLETIER, J., CLOUTIER, J. M. & PELLETIER, J. P. (1990). Cathepsin B and cysteine protease inhibitors in human osteoarthritis. Journal of Orthopaedic Research 8, 336-44.
32. MCDEVITT, C. A. & MILLER, R. R. (1989). Biochemistry, cell biology and immunology of osteoarthritis. Current Opinion in Rheumatology 1, 303-14.
33. MCDEVITT, C. A., PAHL, J. A., AYAD, S., MILLER, R. R., URATSUJI, M. & ANDRISH, J. T. (1988). Experimental osteoarthritic articular cartilage is enriched in guanidine-soluble type VI collagen. Biochemical and Biophysical Research Communications 157, 250-5.
34. MORT, J. S., RECKLIES, A. D. & POOLE, A. R. (1984). Extracellular presence of the lysosomal proteinase cathepsin B in rheumatoid synovium and its activity at neutral pH. Arthritis and Rheumatism 27, 509-15.
35. NGUYEN, Q., MORT, J. S. & ROUGHLEY, P. J. (1990). Cartilage proteoglycan aggregate is degraded more extensively by cathepsin L than by cathepsin B. The Biochemical Journal 266, 569-73.
36. POOL, R. R. & MEAGHER, D. M. (1990). Pathologic findings and pathogenesis of racetrack injuries. Veterinary Clinics of North America Equine Practice 6, 1-30.
37. POOLE, A. R. (1993). Cartilage in health and disease. In: Arthritis and Allied Conditions. eds, D. J. McCarty & W. J. Koopman. pp. 279-333. Philadelphia: Lea & Febiger.
38. POOLE, C. A., MATSUOKA, A. & SCHOFIELD, J. R. (1991). Chondrons from articular cartilage III. Morphologic changes in the cellular microenvironment of chondrons isolated from osteoarthritic cartilage. Arthritis and Rheumatism 34, 22-35.
39. RUCKLIDGE, G. J., MILNE, G. & ROBINS, S. P. (1996). Collagen type X: a component of the surface of normal human, pig and rat articular cartilage. Biochemical and Biophysical Research Communications 224, 297-302.
40. SASAKI, T. & UENO-MATSUDA, E. (1993). Cysteine-proteinase localization in osteoclasts: an immunocytochemical study. Cell and Tissue Research 271, 177-9.
41. SAVAGE, C. J., MCCARTHY, R. N. & JEFFCOTT, L. B. (1993). Effects of dietary energy and protein on induction of dyschondroplasia in foals. Equine Veterinary Journal 16, 74-9.
42. SIRES, U. I., SCHMID, T. M., FLISZAR, C. J., WANG, Z. Q., GLUCK, S. L. & WELGUS, H. G. (1995). Complete degradation of type X collagen requires the combined action of interstitial collagenase and osteoclast-derived cathepsin-B. Journal of Clinical Investigation 95, 2089-95.
43. STALLCUP, W. B., DAHLIN, K. & HEALY, P. (1990). Interaction of the NG2 chondroitin sulphate proteoglycan with type VI collagen. Journal of Cell Biology 111, 3177-88.
44. TRABANDT, A., GAY, R. E., FASSBENDER, H. G. & GAY, S. (1991). Cathepsin B in synovial cells at the site of joint destruction in rheumatoid arthritis. Arthritis and Rheumatism 34, 1444-51.
45. 2F. Journal of Rheumatology 15, 1525-35.
46. VAN NOORDEN, C. J. F. & VOGELS, I. M. C. (1986). Enzyme histochemical reactions in unfixed and undecalcified cryostat sections of mouse knee joints with special reference to arthritic lesions. Histochemistry 86, 127-33.
47. VON DER MARK, K., FRISCHHOLZ, S., AIGNER, T., BEIER, F., BELKE, J., ERDMANN, S. & BURKHARDT, H. (1995). Upregulation of type X collagen expression in osteoarthritic cartilage. Acta Orthopaedica. Scandinavica 66, 125-9.