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Volumn 62, Issue 11, 1998, Pages 2079-2085

The benefits and risks of n-3 polyunsaturated fatty acids

Author keywords

Benefits and risks; Docosahexaenoic acid; Eicosapentaenoic acid; Fish oil; N 3 polyunsaturated fatty acids

Indexed keywords

OMEGA 3 FATTY ACID;

EID: 0032195637     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.62.2079     Document Type: Article
Times cited : (46)

References (57)
  • 1
    • 0019744479 scopus 로고
    • Biochemistry of essential fatty acids
    • Sprecher, H., Biochemistry of essential fatty acids. Prog. Lipid Res., 20, 13-22 (1981).
    • (1981) Prog. Lipid Res. , vol.20 , pp. 13-22
    • Sprecher, H.1
  • 2
    • 0021845562 scopus 로고
    • Fish, fatty acids and human health
    • Glomset, J. A., Fish, fatty acids and human health. N. Engl. J. Med., 312, 1253-1254 (1985).
    • (1985) N. Engl. J. Med. , vol.312 , pp. 1253-1254
    • Glomset, J.A.1
  • 3
    • 0022822322 scopus 로고
    • Are essential fatty acids essential for membrane function?
    • Lee, A. G., East, J. M., and Froud, R. J., Are essential fatty acids essential for membrane function? Prog. Lipid. Res., 25, 41-46 (1986).
    • (1986) Prog. Lipid. Res. , vol.25 , pp. 41-46
    • Lee, A.G.1    East, J.M.2    Froud, R.J.3
  • 4
    • 0030984066 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, part 1: Occurrence, biological activities and applications
    • Gill, I. and Valvety, R., Polyunsaturated fatty acids, part 1: Occurrence, biological activities and applications. TIB Tech., 15, 401-409 (1997).
    • (1997) TIB Tech. , vol.15 , pp. 401-409
    • Gill, I.1    Valvety, R.2
  • 5
    • 0024402737 scopus 로고
    • Essential fatty acid metabolism and requirements during development
    • Uauy, R., Treen, M., and Hoffman, D. R., Essential fatty acid metabolism and requirements during development. Semin. Per-natol., 13, 118-130 (1989).
    • (1989) Semin. Per-Natol. , vol.13 , pp. 118-130
    • Uauy, R.1    Treen, M.2    Hoffman, D.R.3
  • 6
    • 0026319461 scopus 로고
    • Essential fatty acid requirements for normal eye and brain development
    • Uauy, R. and Hoffman, D. R., Essential fatty acid requirements for normal eye and brain development. Semin. Pernatol., 15, 449-455 (1991).
    • (1991) Semin. Pernatol. , vol.15 , pp. 449-455
    • Uauy, R.1    Hoffman, D.R.2
  • 7
    • 0026048644 scopus 로고
    • Essential fatty acid in growth and development
    • Innis, S. M., Essential fatty acid in growth and development. Prog. Lipid. Res., 30, 39-103 (1991).
    • (1991) Prog. Lipid. Res. , vol.30 , pp. 39-103
    • Innis, S.M.1
  • 8
    • 0026094489 scopus 로고
    • Omega-3 fatty acids in health and disease and in growth and development
    • Simopoulos, A. P., Omega-3 fatty acids in health and disease and in growth and development. Am. J. Clin. Nutr., 54, 438-463 (1991).
    • (1991) Am. J. Clin. Nutr. , vol.54 , pp. 438-463
    • Simopoulos, A.P.1
  • 9
    • 0002091037 scopus 로고
    • Effects of fatty acids and lipids in health and disease
    • Galli, C. and Simopoulos, A. P., Effects of fatty acids and lipids in health and disease. World Rev. Nutr. Diet., 76, 1-149 (1994).
    • (1994) World Rev. Nutr. Diet. , vol.76 , pp. 1-149
    • Galli, C.1    Simopoulos, A.P.2
  • 10
    • 0028930444 scopus 로고
    • Fish and heart disease
    • Katan, M. B., Fish and heart disease. N. Engl. J. Med., 332, 1024-1025 (1995).
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1024-1025
    • Katan, M.B.1
  • 11
    • 0021812276 scopus 로고
    • The inverse relation between fish consumption and 20-year mortality from coronary heart disease
    • Kromhout, D., Bosschieter, E. B., and de Coulander, C. L., The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N. Engl. J. Med., 312, 1205-1209 (1985).
    • (1985) N. Engl. J. Med. , vol.312 , pp. 1205-1209
    • Kromhout, D.1    Bosschieter, E.B.2    De Coulander, C.L.3
  • 12
    • 0021926891 scopus 로고
    • Fish comsumption and mortality from coronary heart disease
    • Vollset, S. E., Heuch, L., and Bjelke, E., Fish comsumption and mortality from coronary heart disease. N. Engl. J. Med., 313, 820-821 (1985).
    • (1985) N. Engl. J. Med. , vol.313 , pp. 820-821
    • Vollset, S.E.1    Heuch, L.2    Bjelke, E.3
  • 13
    • 0021926891 scopus 로고
    • Fish comsumption and mortality from coronary heart disease
    • Curb, J. D. and Reed, D. M., Fish comsumption and mortality from coronary heart disease. N. Engl. J. Med., 313, 821-822 (1985).
    • (1985) N. Engl. J. Med. , vol.313 , pp. 821-822
    • Curb, J.D.1    Reed, D.M.2
  • 14
    • 0028924095 scopus 로고
    • Dietary intake of marine n-3 fatty acids, fish intake and the risk of coronary disease among men
    • Ascherio, A., Rimn, E. B., and Stampfer, M. J., Dietary intake of marine n-3 fatty acids, fish intake and the risk of coronary disease among men. N. Engl. J. Med., 332, 977-982 (1995).
    • (1995) N. Engl. J. Med. , vol.332 , pp. 977-982
    • Ascherio, A.1    Rimn, E.B.2    Stampfer, M.J.3
  • 15
    • 0015369932 scopus 로고
    • Plasma lipids and lipoproteins in Greenlandic West-coast Eskimos
    • Bang, H. O. and Dyerberg, J., Plasma lipids and lipoproteins in Greenlandic West-coast Eskimos. Acta. Med. Scand., 192, 85-94 (1972).
    • (1972) Acta. Med. Scand. , vol.192 , pp. 85-94
    • Bang, H.O.1    Dyerberg, J.2
  • 16
    • 0002673687 scopus 로고
    • Lipid metabolism and ischemic heart disease in Greenland Eskimos
    • Bang, H. O. and Dyerberg, J., Lipid metabolism and ischemic heart disease in Greenland Eskimos. Adv. Nutr. Res., 3, 1-21 (1986).
    • (1986) Adv. Nutr. Res. , vol.3 , pp. 1-21
    • Bang, H.O.1    Dyerberg, J.2
  • 17
    • 0025167727 scopus 로고
    • Effect of dietary omega-3 fatty acids on retinal function of very-low-birth weight neonates
    • Uauy, R. D., Birch, D. G., Birch, E. E., Tyson, J. E., and Hoffman, D. R., Effect of dietary omega-3 fatty acids on retinal function of very-low-birth weight neonates. Pediatr. Res., 28, 485-492 (1990).
    • (1990) Pediatr. Res. , vol.28 , pp. 485-492
    • Uauy, R.D.1    Birch, D.G.2    Birch, E.E.3    Tyson, J.E.4    Hoffman, D.R.5
  • 18
    • 0026480375 scopus 로고
    • Essentialness of dietary omega-3 fatty acids for premature infants: Plasma and red blood cell fatty acid composition
    • Hoffman, D. R. and Uauy, R. D., Essentialness of dietary omega-3 fatty acids for premature infants: plasma and red blood cell fatty acid composition. Lipids, 27, 886-895 (1992).
    • (1992) Lipids , vol.27 , pp. 886-895
    • Hoffman, D.R.1    Uauy, R.D.2
  • 19
    • 0026750729 scopus 로고
    • Retinal development in very-low-birth weight infants fed diets differing in omega-3 fatty acids
    • Birch, D. G., Birch, E. E., Hoffman, D. R., and Uauy, R., Retinal development in very-low-birth weight infants fed diets differing in omega-3 fatty acids. Invest. Ophthalmol. Vis. Sci., 33, 2365-2376 (1992).
    • (1992) Invest. Ophthalmol. Vis. Sci. , vol.33 , pp. 2365-2376
    • Birch, D.G.1    Birch, E.E.2    Hoffman, D.R.3    Uauy, R.4
  • 20
  • 22
    • 0027499215 scopus 로고
    • Erythrocyte docosahexaenoic acid correlates with the visual response of healthy, term infants
    • Makrides, M., Simmer, K., Goggin, M., and Gibson, R. A., Erythrocyte docosahexaenoic acid correlates with the visual response of healthy, term infants. Pediatr. Res., 33, 425-427 (1993).
    • (1993) Pediatr. Res. , vol.33 , pp. 425-427
    • Makrides, M.1    Simmer, K.2    Goggin, M.3    Gibson, R.A.4
  • 23
    • 0026768678 scopus 로고
    • Infant cerebral cortex phospholipid fatty acid composition and diet
    • Farquharson, J., Cockburn, F., Patrick, W. A., Jamieson, E. C., and Logan, R. W., Infant cerebral cortex phospholipid fatty acid composition and diet. Lancet, 340, 810-813 (1992).
    • (1992) Lancet , vol.340 , pp. 810-813
    • Farquharson, J.1    Cockburn, F.2    Patrick, W.A.3    Jamieson, E.C.4    Logan, R.W.5
  • 24
    • 0028021727 scopus 로고
    • Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants
    • Makrides, M., Neumann, M. A., Byard, R. W., Simmer, K., and Gibson, R. A., Fatty acid composition of brain, retina, and erythrocytes in breast- and formula-fed infants. Am. J. Clin. Nutr., 60, 189-194 (1994).
    • (1994) Am. J. Clin. Nutr. , vol.60 , pp. 189-194
    • Makrides, M.1    Neumann, M.A.2    Byard, R.W.3    Simmer, K.4    Gibson, R.A.5
  • 25
    • 0029023422 scopus 로고
    • Are long-chain polyunsaturated fatty acids essential nutrients in infancy?
    • Makrides, M., Neumann, M. A., Simmer, K., Pater, J., and Gibson, R. A., Are long-chain polyunsaturated fatty acids essential nutrients in infancy? Lancet, 345, 1463-1468 (1995).
    • (1995) Lancet , vol.345 , pp. 1463-1468
    • Makrides, M.1    Neumann, M.A.2    Simmer, K.3    Pater, J.4    Gibson, R.A.5
  • 27
    • 0026592304 scopus 로고
    • Double-blind, randomized, controlled trial of fish oil supplements in prevention of recurrence of stenosis after coronary angioplasty
    • Bairati, I., Roy, L., and Meyer, F., Double-blind, randomized, controlled trial of fish oil supplements in prevention of recurrence of stenosis after coronary angioplasty. Circulation, 85, 950-956 (1992).
    • (1992) Circulation , vol.85 , pp. 950-956
    • Bairati, I.1    Roy, L.2    Meyer, F.3
  • 28
    • 0026508719 scopus 로고
    • Fish oil supplements for prevention of restenosis after coronary angioplasty
    • Kaul, U., Sanghvi, S., Bahl, V. K., Dev, V., and Wasir, H. S., Fish oil supplements for prevention of restenosis after coronary angioplasty. Int. J. Cardiol., 35, 87-93 (1992).
    • (1992) Int. J. Cardiol. , vol.35 , pp. 87-93
    • Kaul, U.1    Sanghvi, S.2    Bahl, V.K.3    Dev, V.4    Wasir, H.S.5
  • 31
    • 0026689038 scopus 로고
    • Effects of fish oil supplement on blood pressure and serum lipids in patients treated for coronary artery disease
    • Bairati, I., Roy, L., and Meyer, F., Effects of fish oil supplement on blood pressure and serum lipids in patients treated for coronary artery disease. Can. J. Cardiol., 8, 41-46 (1992).
    • (1992) Can. J. Cardiol. , vol.8 , pp. 41-46
    • Bairati, I.1    Roy, L.2    Meyer, F.3
  • 32
    • 0027475140 scopus 로고
    • The effect of fish oil on blood pressure in mild hypertensive subjects: A randomized crossover trial
    • Morris, M. C., Taylor, J. O., Stampfer, M. J., Rosner, B., and Sacks, F. M., The effect of fish oil on blood pressure in mild hypertensive subjects: a randomized crossover trial. Am. J. Clin. Nutr., 57, 59-64 (1993).
    • (1993) Am. J. Clin. Nutr. , vol.57 , pp. 59-64
    • Morris, M.C.1    Taylor, J.O.2    Stampfer, M.J.3    Rosner, B.4    Sacks, F.M.5
  • 33
    • 0027233392 scopus 로고
    • Does supplementation of diet with ‘fish oil’ reduced blood pressure? A meta-analysis of controlled clinical trials
    • Appel, L. J., Miller, E. R., Seidler, A. J., and Whelton, P. K., Does supplementation of diet with ‘fish oil’ reduced blood pressure? A meta-analysis of controlled clinical trials. Arch. Intern. Med., 153, 1429-1438 (1993).
    • (1993) Arch. Intern. Med. , vol.153 , pp. 1429-1438
    • Appel, L.J.1    Miller, E.R.2    Seidler, A.J.3    Whelton, P.K.4
  • 34
    • 0027967424 scopus 로고
    • A controlled trial of fish oil in IgA nephropathy. Mayo Nephrology Collaborative Group
    • Donadio, J. V. J., Bergstralh, E. J., Offord, K. P., Spencer, D. C., and Holley, K. E., A controlled trial of fish oil in IgA nephropathy. Mayo Nephrology Collaborative Group. N. Engl. J. Med., 331, 1194-1199 (1994).
    • (1994) N. Engl. J. Med. , vol.331 , pp. 1194-1199
    • Donadio, J.V.J.1    Bergstralh, E.J.2    Offord, K.P.3    Spencer, D.C.4    Holley, K.E.5
  • 37
    • 0027055976 scopus 로고
    • One-year randomized controlled trial with ome-ga-3 fatty acid-fish oil in clinical renal transplantation
    • Berthoux, F. C., Guerin, C., Burgard, G., Berthoux, P., and Alamartine, E., One-year randomized controlled trial with ome-ga-3 fatty acid-fish oil in clinical renal transplantation. Transplant Proc., 24, 2578-2582 (1992).
    • (1992) Transplant Proc. , vol.24 , pp. 2578-2582
    • Berthoux, F.C.1    Guerin, C.2    Burgard, G.3    Berthoux, P.4    Alamartine, E.5
  • 38
    • 0026778887 scopus 로고
    • The effect of dietary supplementation with fish oil on renal function and the course of early postoperative rejection episodes in cyclosporine-treated renal transplant recipients
    • Homan van der Heide, J. J., Bilo, H. J., Donker, A. J., Wilmink, J. M., Sluiter, W. J., and Tegzess, A. M., The effect of dietary supplementation with fish oil on renal function and the course of early postoperative rejection episodes in cyclosporine-treated renal transplant recipients. Transplantation, 54, 257-263 (1992).
    • (1992) Transplantation , vol.54 , pp. 257-263
    • Homan Van Der Heide, J.J.1    Bilo, H.J.2    Donker, A.J.3    Wilmink, J.M.4    Sluiter, W.J.5    Tegzess, A.M.6
  • 39
    • 0027329064 scopus 로고
    • Effect of dietary fish oil on renal function and rejection in cyclosporine-treated recipients of renal transplants
    • Homan van der Heide, J. J., Bilo, H. J., Donker, J. M., Wilmink, J. M., and Tegzess, A. M., Effect of dietary fish oil on renal function and rejection in cyclosporine-treated recipients of renal transplants. N. Engl. J. Med., 329, 769-773 (1993).
    • (1993) N. Engl. J. Med. , vol.329 , pp. 769-773
    • Homan Van Der Heide, J.J.1    Bilo, H.J.2    Donker, J.M.3    Wilmink, J.M.4    Tegzess, A.M.5
  • 40
    • 0027450823 scopus 로고
    • Pharmacologic intervention to prevent hemodialysis vascular access thrombosis
    • Diskin, C. J., Stokes, T. J. J., and Pennell, A. T., Pharmacologic intervention to prevent hemodialysis vascular access thrombosis. Nephron, 64, 1-26 (1993).
    • (1993) Nephron , vol.64 , pp. 1-26
    • Diskin, C.J.1    Stokes, T.J.J.2    Pennell, A.T.3
  • 42
    • 0026801230 scopus 로고
    • Effect of six months of fish oil supplementation in stable rheumatoid arthritis. A double-blind, controlled study
    • Skoldstam, L., Borjesson, O., Kjallman, A., Seiving, B., and Akesson, B., Effect of six months of fish oil supplementation in stable rheumatoid arthritis. A double-blind, controlled study. Scand. J. Rheumatol., 21, 178-185 (1992).
    • (1992) Scand. J. Rheumatol. , vol.21 , pp. 178-185
    • Skoldstam, L.1    Borjesson, O.2    Kjallman, A.3    Seiving, B.4    Akesson, B.5
  • 44
    • 0028303945 scopus 로고
    • Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study
    • Geusens, P., Wouters, C., Nijs, J., Jiang, Y., and Dequeker, J., Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study. Arthritis Rheum., 37, 824-829 (1994).
    • (1994) Arthritis Rheum. , vol.37 , pp. 824-829
    • Geusens, P.1    Wouters, C.2    Nijs, J.3    Jiang, Y.4    Dequeker, J.5
  • 45
    • 0027315533 scopus 로고
    • Effects of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis
    • Soyland, E., Funk, J., and Rajka, G., Effects of dietary supplementation with very-long-chain n-3 fatty acids in patients with psoriasis. N. Engl. J. Med., 328, 1812-1816 (1993).
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1812-1816
    • Soyland, E.1    Funk, J.2    Rajka, G.3
  • 46
    • 0027173776 scopus 로고
    • Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis
    • Berth-Jones, J. and Graham-Brown, R. A., Placebo-controlled trial of essential fatty acid supplementation in atopic dermatitis. Lancet, 341, 1557-1560 (1993).
    • (1993) Lancet , vol.341 , pp. 1557-1560
    • Berth-Jones, J.1    Graham-Brown, R.A.2
  • 47
    • 0027233009 scopus 로고
    • Fatty acid metabolism in health and disease: The role of delta-6-desaturase
    • Horrobin, D. F., Fatty acid metabolism in health and disease: the role of delta-6-desaturase. AM. J. Clin. Nutr., 57, 732S-736S (1993).
    • (1993) AM. J. Clin. Nutr. , vol.57 , pp. 732S-736S
    • Horrobin, D.F.1
  • 48
    • 84903661016 scopus 로고
    • Present knowledge in nutrition
    • Olson, R. E, Washington, DC
    • Willis, A. L., In “Present knowledge in nutrition”, eds. Olson, R. E, The Nutrition Foundation, Washington, DC, pp. 90-113 (1984).
    • (1984) The Nutrition Foundation , pp. 90-113
    • Willis, A.L.1
  • 49
    • 0024729427 scopus 로고
    • Ingestion of high doses of fish oil increases the susceptibility of cellular membranes to the induction of oxidative stress
    • Garrido, A., Garrido, F., Guerra, R., and Valenzuela, A., Ingestion of high doses of fish oil increases the susceptibility of cellular membranes to the induction of oxidative stress. Lipids, 24, 833-835 (1989).
    • (1989) Lipids , vol.24 , pp. 833-835
    • Garrido, A.1    Garrido, F.2    Guerra, R.3    Valenzuela, A.4
  • 50
    • 0027175717 scopus 로고
    • Increased susceptibility of cellular membranes to the induction of oxidative stress is observed after ingestion of high doses of fish oil: Effect of aging and protective action of dl-a tocopherol supplementation
    • Garrido, A., Garate, M., Campos, R., Villa, A., Nieto, S., and Valenzuela, A., Increased susceptibility of cellular membranes to the induction of oxidative stress is observed after ingestion of high doses of fish oil: effect of aging and protective action of dl-a tocopherol supplementation. Nutr. Biochem., 4, 118-122 (1993).
    • (1993) Nutr. Biochem. , vol.4 , pp. 118-122
    • Garrido, A.1    Garate, M.2    Campos, R.3    Villa, A.4    Nieto, S.5    Valenzuela, A.6
  • 51
    • 0014054470 scopus 로고
    • Vitamin E deficiency: A previously unrecognized cause of hemolytic anemia in the premature infant
    • Oski, F. A. and Barness, L. A., Vitamin E deficiency: a previously unrecognized cause of hemolytic anemia in the premature infant. J. Pediatr., 70, 211-220 (1967).
    • (1967) J. Pediatr , vol.70 , pp. 211-220
    • Oski, F.A.1    Barness, L.A.2
  • 52
    • 0024574297 scopus 로고
    • Menhaden fish oil, n-3 polyunsaturated fatty acids, and protection of newborn rats from oxygen toxicity
    • Sosenko, I. R. S., Innis, S. M., and Frank, L., Menhaden fish oil, n-3 polyunsaturated fatty acids, and protection of newborn rats from oxygen toxicity. Pediatr. Res., 25, 399-404 (1989).
    • (1989) Pediatr. Res. , vol.25 , pp. 399-404
    • Sosenko, I.R.S.1    Innis, S.M.2    Frank, L.3
  • 53
    • 0026343836 scopus 로고
    • Light damage in the rat retina: The effect of dietary deprivation of n-3 fatty acids on acute structural alterations
    • Buch, R. A., Reme, C. A., and Malnoe, A., Light damage in the rat retina: the effect of dietary deprivation of n-3 fatty acids on acute structural alterations. Exp. Eye Res., 53, 741-752 (1991).
    • (1991) Exp. Eye Res. , vol.53 , pp. 741-752
    • Buch, R.A.1    Reme, C.A.2    Malnoe, A.3
  • 55
    • 0016750354 scopus 로고
    • Vitamin E status of Alaskan Eskimos
    • Woo, C. K. W. and Draper, FI. H., Vitamin E status of Alaskan Eskimos. Am. J. Clin. Nutr., 28, 808-813 (1975).
    • (1975) Am. J. Clin. Nutr. , vol.28 , pp. 808-813
    • Woo, C.K.W.1    Draper, F.I.H.2
  • 56
    • 0018581433 scopus 로고
    • Haemostatic function and platelet polyunsaturated fatty acids in Eskimos
    • Dyerburg, J. and Bang, H. O., Haemostatic function and platelet polyunsaturated fatty acids in Eskimos. Lancet, 2, 433-435 (1979).
    • (1979) Lancet , vol.2 , pp. 433-435
    • Dyerburg, J.1    Bang, H.O.2
  • 57
    • 0028226714 scopus 로고
    • Safety and efficacy of omega-3 fatty acids in the nutrition of very low birth weight infants: Soy oil and marine oil supplementation of formula
    • Uauy, R., Hoffman, D. R., Birch, E. E., Birch, D. J., Jameson, D. M., and Tyson, J., Safety and efficacy of omega-3 fatty acids in the nutrition of very low birth weight infants: soy oil and marine oil supplementation of formula. J. Pediatr., 124, 612-620 (1994).
    • (1994) J. Pediatr. , vol.124 , pp. 612-620
    • Uauy, R.1    Hoffman, D.R.2    Birch, E.E.3    Birch, D.J.4    Jameson, D.M.5    Tyson, J.6


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