A His19 to Ala mutant of melanoma growth-stimulating activity is a partial antagonist of the CXCR2 receptor

Journal of Immunology

Volumn 161, Issue 9, 1998, Pages 4944-4949

  Baly, Deborah L ^a   Horuk, Richard ^a,b   Yansura, Daniel G ^a   Simmons, Laura C ^a   Fairbrother, Wayne J ^a   Kotts, Claire ^a   Wirth, Cindy M ^a   Gillece Castro, Beth L ^a   Toy, Karen ^a   Hesselgesser, Joseph ^a,b   Allison, David E ^a  

^a GENENTECH INC   (United States)

^b BAYER AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYCLOOXYGENASE 2; HISTAMINE; ALPHA CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; CHEMOTACTIC FACTOR; CXCL1 PROTEIN, HUMAN; CYTOCHALASIN B; GROWTH PROMOTOR; HYBRID PROTEIN; INTERLEUKIN 8; INTERLEUKIN RECEPTOR; LEUKOCYTE ANTIGEN; LEUKOCYTE ELASTASE; SIGNAL PEPTIDE;

ARTICLE; CALCIUM CELL LEVEL; COMPETITIVE INHIBITION; DRUG RECEPTOR BINDING; ENZYME INDUCTION; GROWTH REGULATION; HUMAN; HUMAN CELL; MELANOMA; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; TUMOR GROWTH; AMINO ACID SUBSTITUTION; CALCIUM SIGNALING; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; NEUTROPHIL; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANTIGENS, CD; CALCIUM SIGNALING; CELL LINE; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; CYTOCHALASIN B; GROWTH SUBSTANCES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-8; LEUKOCYTE ELASTASE; NEUTROPHILS; RECEPTORS, CHEMOKINE; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-8A; RECEPTORS, INTERLEUKIN-8B; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0032194954     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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