CD16 cross-linking blocks rearrangement of the TCRβ locus and development of αβ T cells and induces development of NK cells from thymic progenitors

Journal of Immunology

Volumn 161, Issue 7, 1998, Pages 3325-3329

  Durum, Scott K ^a   Lee, Chong Kil ^a   Geiman, Theresa M ^b   Murphy, William J ^b   Muegge, Kathrin ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD16 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; DNA; T LYMPHOCYTE RECEPTOR;

ANIMAL TISSUE; ARTICLE; CELL MATURATION; CONTROLLED STUDY; CROSS LINKING; EMBRYO; FLOW CYTOMETRY; GENE REARRANGEMENT; MOUSE; NATURAL KILLER CELL; NONHUMAN; ORGAN CULTURE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STEM CELL; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; ANTIBODIES, BLOCKING; CELL DIFFERENTIATION; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; IMMUNE SERA; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, IGG; STEM CELLS; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 0032194169     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Scollay, R., J. Smith, and V. Stauffer. 1986. Dynamics of early T cells: prothymocyte migration and proliferation in the adult mouse thymus. Immunol. Rev. 91:129.
2. Storb, U., and A. M. Kruisbeek. 1996. Lymphocyte development. Curr. Opin. Immunol. 8:155.
3. Shortman, K., and L. Wu. 1996. Early T lymphocyte progenitors. Annu. Rev. Immunol. 14:29.
4. Lanier, L. L., H. Spits, and J. H. Phillips. 1992. The developmental relationship between NK cells and T cells. Immunol. Today 13:392.
5. Georgopoulos, K., M. Bigby, J. H. Wang, A. Molnar, P. Wu, S. Winandy, and A. Sharpe. 1994. The Ikaros gene is required for the development of all lymphoid ' lineages. Cell 79:143.
6. Cao, X., E. W. Shores, J. Hu-Li, M. R. Anver, B. L. Kelsall, S. M. Russell, J. Drago, M. Noguchi, A. Grinberg, E. T. Bloom, et al. 1995. Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain. Immunity 2:223.
7. Park, S. Y., K. Saimo, T. Takahashi, M. Osawa, H. Arase, N. Hirayama, K. Miyake, H. Nakauchi, T. Shirasawa, and T. Saito. 1995. Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. Immunity 3:771.
8. Wang, B, C. Biron, J. She, K. Higgins, M.-J. Sunshine, E. Lacy, N. Lonberg, and C. Terhorst. 1994. A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene. Proc. Natl. Acad. Sci. USA 91:9402.
9. Garni-Wagner, B. A., P. L. Witte, M. M. Tutt, W. A. Kuziel, P. W. Tucker, M. Bennett, and V. Kumar. 1990. Natural killer cells in the thymus: studies in mice with severe combined immune deficiency. J. Immunol. 144:796.
10. Rodewald, H.-R., P. Moingeon, J. L. Lucich, C. Dosiou, P. Lopez, and E. L. Reinherz. 1992. A population of early fetal thymocytes expressing FcγRII/III contains precursors of T lymphocytes and natural killer cells. Cell 69:139.
11. Leclercq, G., B. Debacker, M. DeSmedt, and J. Plum. 1996. Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells. J. Exp. Med. 184:325.
12. Sanchez, M., M. E. Muench, M. G. Roncarolo, L. L. Lanier, and J. H. Phillips. 1994. Identification of a common T/natural killer cell progenitor in human fetal thymus. J. Exp. Med. 180:569.
13. 1 integrin in murine thymocytes. J. Immunol. 159:2259.
14. Muegge, K., M. Vila, and S. K. Durum. 1993. Interleukin-7: a cofactor for V(D)J recombination of the T cell receptor β gene. Science 261:93.
15. - murine thymocytes: in vivo developmental kinetics and T cell receptor β chain rearrangement status. J. Exp. Med. 177:1079.
16. Candéias, S., K. Muegge, and S. K. Durum. 1996. Junctional diversity in signal joints from T cell receptor β and δ loci via terminal deoxynucleotidyl transferase and exonucleolytic activity. J. Exp. Med. 184:1919.
17. Surh, C. D., and J. Sprent. 1994. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372:100.
18. Candéias, S., K. Muegge, and S. K. Durum. 1997. IL-7 receptor and VDJ recombination: trophic versus mechanistic actions. Immunity 6:501.
19. Candéias, S., J. J. Peschon, K. Muegge, and S. K. Durum. 1997. Defective T-cell receptor y gene rearrangement in interleukin 7 receptor knockout mice. Immunol. Lett. 57:9.
20. Ravetch, J. V., and J.-P. Kinet. 1991. Fc receptors. Annu. Rev. Immunol. 9:457.