Determination of p185 and adenylosuccinate lyase (ASL) activity in preneoplastic colon lesions and intestinal mucosa of human subjects

Clinical Biochemistry

Volumn 31, Issue 7, 1998, Pages 523-528

  Terzuoli, Lucia ^a   Carlucci, Filippo ^a   De Martino, Antonio ^b   Frosi, Barbara ^a   Porcelli, Brunetta ^a   Minacci, Chiara ^b   Vernillo, Remo ^b   Baldi, Lucia ^a   Marinello, Enrico ^a,c   Pagani, Roberto ^a   Tabucchi, Antonella ^a  

^a Inst of Biochemistry and Enzymology   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c Ist di Biochimica e di Enzimologia   (Italy)

Author keywords

Adenylosuccinate lyase; Colorectal cancer; HER2 gene; HPLC; Immunohistochemical analysis; Oncogenes; P185; Polyps; Tubular adenoma

Indexed keywords

ADENYLOSUCCINATE LYASE; TUMOR MARKER;

ARTICLE; CELL TRANSFORMATION; COLON CANCER; DRUG DETERMINATION; EARLY DIAGNOSIS; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTESTINE MUCOSA; ONCOGENE; PRECANCER; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

ADENOMA; ADENOSINE MONOPHOSPHATE; ADENYLOSUCCINATE LYASE; ADULT; AGED; COLON; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; MIDDLE AGED; RECEPTOR, ERBB-2; TUMOR MARKERS, BIOLOGICAL;

EID: 0032192468     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(98)00058-7     Document Type: Article

References (26)

1. Coussen L., Yang-Feng T.L., Liao Y.K., et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with new oncogene. Science (Wash. DC). 230:1985;1132-1139.
2. Stern D.F., Hefferman P.A., Weinberg R.A. p185 a product of the NEU protooncogene, is a receptor-like protein associated with tyrosine kinase activity. Mol Cell Biol. 6:1986;1729-1740.
3. Di Fiore P.P., Pierce J.H., Kraus M.H., Segatto O., King C.R., Aaronson S.A. ErbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science. 237:1987;178-182.
4. King C.R., Kraus M., Aaronson S.A. Amplification of a novel v-erbB related gene in human mammary carcinoma. Science (Wash.DC). 229:1985;974-976.
5. Semba K., Kamata N., Toyoshima K., Yamamoto T. A v-erbB related protooncogene, c-erbB-2, is distinct from the c-erb-1 epidermal growth factor receptor gene and is amplified in human salivary gland adenocarcinoma. Proc Natl Acad Sci USA. 82:1985;6497-6501.
6. Yokota J., Toyoshima K., Yamamoto T., Terada M., Battifora H., Cline M.J. Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo. Lancet. 2:1986;765-766.
7. Slamon D.J., Clark G.M., Wong S.C., Levin W.J., Ullrich A., McGuire L. Human breast cancer correlation of relapse and survival with amplification of the HER-2/NEU oncogene . Science. 235:1987;177-182.
8. Cheever M.A., Disis M.L., Bernard H., et al. Immunity to oncogenic proteins. Immunol Rev. 145:1995;34-59.
9. Pupa S.M., Menard S., Andreola S., et al. Antibody response against the c-erbB-2 oncoprotein in breast carcinoma patients. Cancer Res. 53:1993;5864-5866.
10. Disis M.L., Calenoff E., McLaughlin G., et al. Existent T-cell and antibody immunity to HER-2/neu protein in patients with breast cancer. Cancer Res. 54:1994;16-20.
11. Weber G. Enzymes of purine metabolism in cancer. Clin Biochem. 16:1983;57-63.
12. Van den Berghe G., Bontemps F., Vincent M.F. Purine nucleotide cycle, molecular defects and therapy. Adv Exp Med Biol. 309B:1991;281-285.
13. 4 cells. Inhibition of adenylosuccinate lyase by fluoro analogs of its substrates. J Biol Chem. 261:1986;13637-13642.
14. Gendron N., Breton R., Champagne N., La Pointe J. Adenylosuccinate lyase of Bacillus subtilis regulates the activity of the glutamyl-tRNA synthetase. J Proc Natl Acad Sci USA. 89:1992;5389-5392.
15. Jackson R.C., Morris H.P., Weber G. Enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors. Cancer Res. 37:1977;3057-3065.
16. Weber G. Biochemical strategy of cancer cells and the design of chemotherapy G.H.A. Clowes Memorial Lecture . Cancer Res. 43:1983;3466-3492.
17. Bardot V., Dutrillaux A.M., Delattre J.Y., et al. Purine and pyrimidine metabolism in human gliomas relation to chromosomal aberrations . Br J Cancer. 70:1994;212-218.
18. Reed V.L., Mack D.O., Smith L.D. Adenylosuccinate lyase as an indicator of breast and prostate malignancies a preliminary report . Clin Biochem. 20:1987;349-351.
19. Hsu S.M., Raine L., Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J Histochem Cytochem. 29:1981;577-580.
20. Digiesi G., Giacomini P., Mariani M., Nicotra M.R., Segatto O. Production and characterization of murine Mabs to the extracellular domain of human neu oncogene product GP185HER2. Hybridoma. 11:1992;519-527.
21. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal Biochem. 72:1976;248-254.
22. Natali P.G., Nicotra M.R., Bigotti A., Venturo I., Slamon D.J., Feundly B.M., Ullrich A. Expression of the p185 encoded by Her2 oncogene in normal and transformed human tissue. Int J Cancer. 45:1990;457-461.
23. Jackson R.C., Morris H.P., Weber G. Neoplastic transformation-linked alterations in adenylosuccinate synthetase activity. Biochem Biophys Res Comm. 66:1975;528-532.
24. Lorenzini L, De Martino A, Testi W et al. Behavior of enzymes involved in purine nucleotide metabolism in tumors. In: Purine and Pyrimidine Metabolism in Man VIII. Pp. 213-18, New York: Plenum Press, 1995.
25. Soreide J.A., Lea O.A., Kvinnsland S. Cytosol protein content and prognosis in operable breast cancer. Correlations with steroid hormone receptors and other prognostic factors. Breast Cancer Res Treat. 20:1991;25-32.
26. Master C.L. Minireview the turnover profile of an enzyme . Int J Biochem. 14:1982;685-689.