The superiority of pinacidil over adenosine cardioplegia in blood- perfused isolated hearts

Annals of Thoracic Surgery

Volumn 66, Issue 4, 1998, Pages 1329-1335

  Jayawant, A Mark ^b   Damiano Jr , Ralph J ^a  

^a GEISINGER HEALTH SYSTEM   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; PINACIDIL; POTASSIUM CHANNEL STIMULATING AGENT;

ANIMAL MODEL; ANIMAL TISSUE; CARDIOPLEGIA; CONFERENCE PAPER; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; FEMALE; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART PROTECTION; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0032192036     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-4975(98)00772-3     Document Type: Conference Paper

References (33)

1. 1. Drewnowska K, Clemo HF, Baumgarten CM. Prevention of myocardial intracellular edema induced by St. Thomas' Hospital cardioplegic solution. J Mol Cell Cardiol 1991;23: 1215-21.
2. 2. Kleber AG, Oetliker H. Cellular aspects of early contractile failure in ischemia. In: Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE, eds. The heart and cardiovascular system. New York: Raven, 1992:1975-2020.
3. 3. Reimer KA, Jennings RB. Myocardial ischemia, hypoxia and infarction. In: Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE, eds. The heart and cardiovascular system. New York: Raven, 1992:1973-75.
4. 4. Blaustein MP, Goldman WF, Fontana G, et al. Physiologic roles of the sodium-calcium exchanger in nerve and muscle. Ann N Y Acad Sci 1991;639:254-74.
5. 5. Bolli R. Mechanism of myocardial stunning. Circulation 1990;82:723-8.
6. 6. Gettes LS, Cascio WE. Effect of acute ischemia on cardiac electrophysiology. In: Fozzard HA, Haber E, Jennings RB, Katz AM, Morgan HE, eds. The heart and cardiovascular system. New York: Raven, 1992:2021-54.
7. 7. Foglia RP, Steed DL, Follette DM, DeLand E, Buckberg GD. Iatrogenic myocardial edema with potassium cardioplegia. J Thorac Cardiovasc Surg 1979;78:217-22.
8. 8. Jayawant AM, Lawton JS, Hsia P, Damiano RJ. Hyperpolarized cardioplegic arrest with nicorandil: advantages over other potassium channel openers. Circulation 1997;96(Suppl 2):240-6.
9. 9. Lawton J, Sepic J, Allen C, Hsia P, Damiano R. Myocardial protection with potassium channel openers is as effective as St. Thomas' solution in the rabbit heart. Ann Thorac Surg 1996;62:31-9.
10. 10. Maskal SL, Cohen NM, Hsia PW, Wechsler AW, Damiano RJ. Hyperpolarized cardiac arrest with a potassium-channel opener, aprikalim. J Thorac Cardiovasc Surg 1995;110: 1083-95.
11. 11. Schubert R, Vetter H, Owen P, Reichart B, Opie LH. Adenosine cardioplegia. J Thorac Cardiovasc Surg 1989;98: 1057-65.
12. 12. Gross GJ, Auchampach JA. Role of ATP dependent potassium channels in myocardial ischaemia. Cardiovasc Res 1992;26:1011-6.
13. 13. Lawton JS, McClain LC, Maier GW, Hsia P, Damiano RJ. Postischemic myocardial oxygen consumption in hearts protected with hyperpolarizing cardioplegia. Circulation 1996; 94(Suppl 1):115.
14. 14. Boiling SF, Bies LE, Bove EL, Gallagher KP. Augmenting intracellular adenosine improves myocardial recovery. J Thorac Cardiovasc Surg 1990;99:469-74.
15. 15. Boiling SF, Childs KF, Ning X. Adenosine's effect on myocardial functional recovery: substrate or signal? J Surg Res 1994;57:591-5.
16. 16. Grover GJ, D'Alonzo AJ, Hess T, Sleph PG, Darbenzio RB. Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening. Cardiovasc Res 1995;30:731-8.
17. 17. Saltman AE, Krukenkamp IB, Gaudette GR, Levitsky S. Phenylephrine reverses the vasodilatory effect of potassium channel openers yet preserves their preconditioning properties [Abstract]. Circulation 1996;94(Suppl 1):415.
18. 18. Toombs CF, McGee S, Johnston WE, Vinten-Johansen J. Myocardial protective effects of adenosine: infarct size reduction with pretreatment and continued receptor stimulation during ischemia. Circulation 1992;86:986-94.
19. 1 receptor mediated protection of the globally ischemic isolated rat heart. J Mol Cell Cardiol 1990;22:39-47.
20. 1-Adrenoceptor activation increases ecto-5′-nucleotidase activity and adenosine release in rat cardiomyocytes by activating protein kinase C. Circulation 1995;91:2226-34.
21. 21. Vinten-Johansen J, Nakanishi K, Zhao ZQ, McGee DS, Tan P. Acadesine improves surgical myocardial protection with blood cardioplegia in ischemically injured canine hearts. Circulation 1993;88(pt 2):350-8.
22. 22. Lasley RD, Mentzer RM. Protective effects of adenosine in the reversibly injured heart. Ann Thorac Surg 1995;60:843-6.
23. 23. Hudspeth DA, Nakanishi K, Vinten-Johansen J, et al. Adenosine in blood cardioplegia prevents postischemic dysfunction in ischemically injured hearts. Ann Thorac Surg 1994;58: 1637-44.
24. 24. Moak JP. Pharmacology and electrophysiology of antiarrhythmic drugs. In: Gillette PC, Garson A Jr, eds. Pediatric arrhythmias: electrophysiology and pacing. Philadelphia: Saunders, 1990:100-5.
25. 1 receptors by G proteins in rat ventricular myocytes. Am J Physiol 1990;259:H820-6.
26. ATP channels. Circulation 1994;89:1229-36.
27. 27. Toombs CF, McGee DS, Johnston WE, Vinten-Johansen J. Protection from ischaemic-reperfusion injury with adenosine pretreatment is reversed by inhibition of ATP sensitive potassium channels. Cardiovasc Res 1993;27:623-9.
28. 28. Xu J, Wang L, Hurt CM, Pelleg A. Endogenous adenosine does not activate ATP-sensitive potassium channels in the hypoxic guinea pig ventricle in vivo. Circulation 1994;89: 1209-16.
29. 29. Song Y, Belardinelli L. Electrophysiological and functional effects of adenosine on ventricular myocytes of various mammalian species. Am J Physiol 1996;271:C1233-43.
30. 30. Cohen NM, Allen CA, Hsia P, Nixon TE, Wise RM, Damiano RJ. Electrophysiological consequences of hyperkalemic cardioplegia during surgical ischemia. Ann Thorac Surg 1994; 57:1076-83.
31. 31. D'Alonzo AJ, Darbenzio RB, Parham CS, Grover GJ. Effects of intracoronary cromakalim on postischaemic contractile function and action potential duration. Cardiovasc Res 1992; 26:1046-53.
32. 32. Gollasch M, Rostislav B, Ried C, et al. Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells. J Pharmacol Exp Ther 1995;275:681-92.
33. 33. Ryman R, Petersson J, Andersson K, Brandt L, Hogestatt ED. Effects of pinacidil on cerebral and mesenteric arteries -influence of the endothelium. Naunyn-Schmiedebergs Arch Pharmacol 1993;348:298-304.