-
1
-
-
0029999787
-
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules
-
Alonso, A.C., Grundke-Iqbal, I., and Iqbal, K. (1996) Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nat. Med., 2:783-787.
-
(1996)
Nat. Med.
, vol.2
, pp. 783-787
-
-
Alonso, A.C.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
2
-
-
1842415999
-
Role of glycosaminoglycans in determining the helicity of paired helical filaments
-
Arrasate, M., Perez, M., Valpuesta, J.M., and Avila, J. (1997) Role of glycosaminoglycans in determining the helicity of paired helical filaments. Am. J. Pathol., 151:1-8.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1-8
-
-
Arrasate, M.1
Perez, M.2
Valpuesta, J.M.3
Avila, J.4
-
3
-
-
0026740795
-
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
-
Arriagada, P.A., Growdon, J.H., Hedley-White, E.T., and Hyman, B.T. (1992) Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology, 42:631-639.
-
(1992)
Neurology
, vol.42
, pp. 631-639
-
-
Arriagada, P.A.1
Growdon, J.H.2
Hedley-White, E.T.3
Hyman, B.T.4
-
4
-
-
0024587074
-
Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease
-
Bancher, C., Brunner, C., Lassmann, H., Budka, H., Jellinger, K., Wiche, G., Setelberger, F., Grundke-Iqbal, I., Iqbal, K., and Wisniewski, H.M. (1989) Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Res., 477:90-99.
-
(1989)
Brain Res.
, vol.477
, pp. 90-99
-
-
Bancher, C.1
Brunner, C.2
Lassmann, H.3
Budka, H.4
Jellinger, K.5
Wiche, G.6
Setelberger, F.7
Grundke-Iqbal, I.8
Iqbal, K.9
Wisniewski, H.M.10
-
5
-
-
0026030994
-
Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease
-
Bancher, C., Grundke-Iqbal, I., Iqbal, K., Fried, V.A., Smith, H.T., and Wisniewski, H.M. (1991) Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease. Brain Res., 539:11-18.
-
(1991)
Brain Res.
, vol.539
, pp. 11-18
-
-
Bancher, C.1
Grundke-Iqbal, I.2
Iqbal, K.3
Fried, V.A.4
Smith, H.T.5
Wisniewski, H.M.6
-
6
-
-
0028879044
-
Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: Implication of phosphoprotein phosphatase involvement
-
Baum, L. Seger, R., Woodgett, J.R., Kawabata, S., Maruyama, K., Koyama, M., Silver, J., and Saitoh, T. (1995) Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement. Mol. Brain Res., 34:1-17.
-
(1995)
Mol. Brain Res.
, vol.34
, pp. 1-17
-
-
Baum, L.1
Seger, R.2
Woodgett, J.R.3
Kawabata, S.4
Maruyama, K.5
Koyama, M.6
Silver, J.7
Saitoh, T.8
-
7
-
-
0026551711
-
The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region
-
Biernat, J., Mandelkow, E.-M., Schröter, C., Lichtenberg-Kraag, B., Steiner, B., Berling, B., Meyer, H., Mercken, M., Vandermeeren, A., Goedert, M., and Mandelkow, E. (1992) The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region. EMBO J., 11:1593-1597.
-
(1992)
EMBO J.
, vol.11
, pp. 1593-1597
-
-
Biernat, J.1
Mandelkow, E.-M.2
Schröter, C.3
Lichtenberg-Kraag, B.4
Steiner, B.5
Berling, B.6
Meyer, H.7
Mercken, M.8
Vandermeeren, A.9
Goedert, M.10
Mandelkow, E.11
-
8
-
-
0027338266
-
262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
-
262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding. Neuron, 11:153-163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
9
-
-
0024988546
-
Molecular analysis of neurofibrillary degeneration in Alzheimer's disease: An immunocytochemical study
-
Bondareff, W., Wischick, C.M., Novak, M., Amos, W.B., Klug, A., and Roth, M. (1990) Molecular analysis of neurofibrillary degeneration in Alzheimer's disease: An immunocytochemical study. Am. J. Pathol., 137:711-723.
-
(1990)
Am. J. Pathol.
, vol.137
, pp. 711-723
-
-
Bondareff, W.1
Wischick, C.M.2
Novak, M.3
Amos, W.B.4
Klug, A.5
Roth, M.6
-
10
-
-
0029076249
-
Absence of abnormal hyperphosphorylation of tau in intracellular tangles in Alzheimer's disease
-
Bondareff, W., Harrington, C.R., Wischick, C.M. Hauser, D.L., and Roth, M. (1995) Absence of abnormal hyperphosphorylation of tau in intracellular tangles in Alzheimer's disease. J. Neuropathol. Exp. Neural., 54:657-663.
-
(1995)
J. Neuropathol. Exp. Neural.
, vol.54
, pp. 657-663
-
-
Bondareff, W.1
Harrington, C.R.2
Wischick, C.M.3
Hauser, D.L.4
Roth, M.5
-
11
-
-
0025863618
-
Neuropathological staging of Alzheimer related changes
-
Berl.
-
Braak, H., and Braak, E. (1991) Neuropathological staging of Alzheimer related changes. Acta Neuropathol. (Berl.), 82:239-259.
-
(1991)
Acta Neuropathol.
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
12
-
-
0028362458
-
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
-
Berl.
-
Braak, E., Braak, E., and Mandelkow, E.M. (1994) A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol. (Berl.), 87:554-567.
-
(1994)
Acta Neuropathol.
, vol.87
, pp. 554-567
-
-
Braak, E.1
Braak, E.2
Mandelkow, E.M.3
-
13
-
-
0029975481
-
Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease
-
Braak, H., Braak, E., Bohl, J., and Reintjes, R. (1996) Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease. Neurosci. Lett., 210:87-90.
-
(1996)
Neurosci. Lett.
, vol.210
, pp. 87-90
-
-
Braak, H.1
Braak, E.2
Bohl, J.3
Reintjes, R.4
-
14
-
-
0023939251
-
Normal ageing, impaired cognitive function, and senile dementia of the Alzheimer's type: A continuum?
-
Brayne, C., and Calloway, P. (1988) Normal ageing, impaired cognitive function, and senile dementia of the Alzheimer's type: A continuum? Lancet, 1:1265-1267.
-
(1988)
Lancet
, vol.1
, pp. 1265-1267
-
-
Brayne, C.1
Calloway, P.2
-
15
-
-
0025977281
-
Straight and paired helical filaments in Alzheimer disease have a common structural unit
-
Crowther, R.A. (1991) Straight and paired helical filaments in Alzheimer disease have a common structural unit. Proc. Natl. Acad. Sci. USA, 88:2288-2292.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2288-2292
-
-
Crowther, R.A.1
-
16
-
-
0026512066
-
Identification of normal and pathological aging in prospectively studied non-demented elderly humans
-
Dickson, D.W., Crystal, H.A., Mattiace, L.A., Masur, D.M., Blau, A.D., Davies, P., Yen, S.-H., and Aronson, H. (1991) Identification of normal and pathological aging in prospectively studied non-demented elderly humans. Neurobiol. Aging, 13:179-189.
-
(1991)
Neurobiol. Aging
, vol.13
, pp. 179-189
-
-
Dickson, D.W.1
Crystal, H.A.2
Mattiace, L.A.3
Masur, D.M.4
Blau, A.D.5
Davies, P.6
Yen, S.-H.7
Aronson, H.8
-
17
-
-
0027534862
-
Lack of the carboxy terminal sequence of tau in ghost tangles of Alzheimer's disease
-
Endoh, R., Ogawara, M., Iwatsubo, T., Nakano, I., and Mori, H. (1993) Lack of the carboxy terminal sequence of tau in ghost tangles of Alzheimer's disease. Brain Res., 601:164-172.
-
(1993)
Brain Res.
, vol.601
, pp. 164-172
-
-
Endoh, R.1
Ogawara, M.2
Iwatsubo, T.3
Nakano, I.4
Mori, H.5
-
18
-
-
0017258238
-
Senile changes in the human neocortex and hippocampus compared by the use of the electron and light microscopes
-
Gibson, P.H., Stones, M., and Tomlinson, B.E. (1976) Senile changes in the human neocortex and hippocampus compared by the use of the electron and light microscopes. J. Neurol. Sci., 27:389-405.
-
(1976)
J. Neurol. Sci.
, vol.27
, pp. 389-405
-
-
Gibson, P.H.1
Stones, M.2
Tomlinson, B.E.3
-
19
-
-
0027217679
-
The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development
-
Goedert, M., Jakes, R., Crowther, R.A., Six, J., Lübke, U., Vandermeeren, M., Cras, P., Trojanowski, J.Q., and Lee, V.M.-Y. (1993) The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development. Proc. Natl. Acad. Sci. USA, 90:5066-5070.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5066-5070
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Six, J.4
Lübke, U.5
Vandermeeren, M.6
Cras, P.7
Trojanowski, J.Q.8
Lee, V.M.-Y.9
-
20
-
-
0027984739
-
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein
-
Goedert, M., Jakes, R., Crowther, R.A., Cohen, P., Van Mechelen, E., Vandermeeren, M., and Crass, P. (1994) Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein. Biochem. J., 301:871-877.
-
(1994)
Biochem. J.
, vol.301
, pp. 871-877
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Cohen, P.4
Van Mechelen, E.5
Vandermeeren, M.6
Crass, P.7
-
21
-
-
0029907548
-
Assembly of microtubule associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
-
Goedert, M., Jakes, R., Spillantini, M.G., Hasegawa, M., Smith, M.J., and Crowther, R.A. (1996) Assembly of microtubule associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature, 383:550-553.
-
(1996)
Nature
, vol.383
, pp. 550-553
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
Hasegawa, M.4
Smith, M.J.5
Crowther, R.A.6
-
22
-
-
0028965635
-
Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform
-
Gotz, J., Probst, A., Spillantini, M.G., Schäfer, T., Jakes, R., Bürki, K., and Goedert, M. (1995) Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform. EMBO J., 14:1304-1313.
-
(1995)
EMBO J.
, vol.14
, pp. 1304-1313
-
-
Gotz, J.1
Probst, A.2
Spillantini, M.G.3
Schäfer, T.4
Jakes, R.5
Bürki, K.6
Goedert, M.7
-
23
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal, I., Iqbal, K., Tung, Y.C., Quinlan, H., Wisniewski, H.M., and Binder, L.I. (1986) Abnormal phosphorylation of the microtubule-associated protein tau in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA, 83:4913-4917.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, H.4
Wisniewski, H.M.5
Binder, L.I.6
-
24
-
-
0026787130
-
Protein sequence and mass spectrometric analysis of tau in the Alzheimer's disease brain
-
Hasegawa, M., Morishima-Kawashima, M., Takio, K., Suzuki, M., Titani, K., and Ihara, Y. (1992) Protein sequence and mass spectrometric analysis of tau in the Alzheimer's disease brain. J. Biol. Chem., 267:17047-17054.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17047-17054
-
-
Hasegawa, M.1
Morishima-Kawashima, M.2
Takio, K.3
Suzuki, M.4
Titani, K.5
Ihara, Y.6
-
25
-
-
0030784929
-
Atypical form of Alzheimer's disease with prominent posterior cortical atrophy: A review of lesion distribution and circuit disconnection in cortical visual pathways
-
Hof, P.R., Vogt, B.A., Bouras, C., and Morrison, J.H. (1997) Atypical form of Alzheimer's disease with prominent posterior cortical atrophy: A review of lesion distribution and circuit disconnection in cortical visual pathways, Vision Res., 37:3609-3625.
-
(1997)
Vision Res.
, vol.37
, pp. 3609-3625
-
-
Hof, P.R.1
Vogt, B.A.2
Bouras, C.3
Morrison, J.H.4
-
26
-
-
0025107676
-
Memory-related neural systems in Alzheimer's disease: An anatomic study
-
Hyman, B.T., Van Hoessen, G., and Damasio, A.R. (1990) Memory-related neural systems in Alzheimer's disease: An anatomic study. Neurology, 40:1721-1730.
-
(1990)
Neurology
, vol.40
, pp. 1721-1730
-
-
Hyman, B.T.1
Van Hoessen, G.2
Damasio, A.R.3
-
27
-
-
0030842576
-
Neuropathological staging of Alzheimer-related lesions: The challenge of establishing relations to age
-
Jellinger, K.A. (1997) Neuropathological staging of Alzheimer-related lesions: The challenge of establishing relations to age. Neurobiol. Aging, 18:369-375.
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 369-375
-
-
Jellinger, K.A.1
-
28
-
-
0022414054
-
Diagnosis of Alzheimer's disease
-
Khachaturian, Z.S. (1985) Diagnosis of Alzheimer's disease. Arch. Neurol., 42:1097-1105.
-
(1985)
Arch. Neurol.
, vol.42
, pp. 1097-1105
-
-
Khachaturian, Z.S.1
-
29
-
-
0027361281
-
Microtubule-associated tau: Abnormal phosphorylation of non-paired helical filaments pool in Alzheimer's disease
-
Köpke, E., Tung, Y.C., Shaikh, S., Alonso, A.C., Iqbal, K., and Grundke-Iqbal, I. (1993) Microtubule-associated tau: Abnormal phosphorylation of non-paired helical filaments pool in Alzheimer's disease. J. Biol. Chem., 268:24373-24384.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24373-24384
-
-
Köpke, E.1
Tung, Y.C.2
Shaikh, S.3
Alonso, A.C.4
Iqbal, K.5
Grundke-Iqbal, I.6
-
30
-
-
0009364134
-
Microtubule-associated protein tau is a major antigenic component of paired helical filaments in Alzheimer disease
-
Kosik, K.S., Joachim, C.L., and Selkoe, D.J. (1986) Microtubule-associated protein tau is a major antigenic component of paired helical filaments in Alzheimer disease. Proc. Natl. Acad. Sci. USA, 83:4044-4048.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4044-4048
-
-
Kosik, K.S.1
Joachim, C.L.2
Selkoe, D.J.3
-
31
-
-
0024109687
-
Epitopes that span the tau molecule are shared with paired helical filaments
-
Kosik, K.S., Orecchio, L.D., Binder, L., Trojanowski, J.Q., Lee, V.M.-L., and Lee, G. (1988) Epitopes that span the tau molecule are shared with paired helical filaments. Neuron, 1:817-825.
-
(1988)
Neuron
, vol.1
, pp. 817-825
-
-
Kosik, K.S.1
Orecchio, L.D.2
Binder, L.3
Trojanowski, J.Q.4
Lee, V.M.-L.5
Lee, G.6
-
32
-
-
0028297078
-
Mass and physical dimensions of two distinct populations of paired helical filaments
-
Ksiezak-Reding, H., and Wall, J.S. (1994) Mass and physical dimensions of two distinct populations of paired helical filaments. Neurobiol. Aging, 15:11-19.
-
(1994)
Neurobiol. Aging
, vol.15
, pp. 11-19
-
-
Ksiezak-Reding, H.1
Wall, J.S.2
-
33
-
-
0028242639
-
Tau immunoreactivity and SDS solubility of two populations of paired helical filaments that differ in morphology
-
Ksiezak-Reding, H., Morgan, K., and Dickson, D.W. (1994) Tau immunoreactivity and SDS solubility of two populations of paired helical filaments that differ in morphology. Brain Res., 649:185-196.
-
(1994)
Brain Res.
, vol.649
, pp. 185-196
-
-
Ksiezak-Reding, H.1
Morgan, K.2
Dickson, D.W.3
-
34
-
-
0029037565
-
Examination of phosphorylated tau protein as a PHF-precursor at early stage Alzheimer's disease
-
Lai, R.Y.K., Gertz, H.N.J., Wischick, D.J., Xuereb, J.H., Mukaetova-Ladinska, E.B., Harrington, C.R., Edwards, P.C., Menc, R., Paykel, E.S., Brayne, C., Huppert, F.A., Roth, M., and Wischick, C.M. (1995) Examination of phosphorylated tau protein as a PHF-precursor at early stage Alzheimer's disease. Neurobiol. Aging, 3:433-445.
-
(1995)
Neurobiol. Aging
, vol.3
, pp. 433-445
-
-
Lai, R.Y.K.1
Gertz, H.N.J.2
Wischick, D.J.3
Xuereb, J.H.4
Mukaetova-Ladinska, E.B.5
Harrington, C.R.6
Edwards, P.C.7
Menc, R.8
Paykel, E.S.9
Brayne, C.10
Huppert, F.A.11
Roth, M.12
Wischick, C.M.13
-
35
-
-
0028065142
-
Analysis of microtubule-associated protein tau glycation in paired helical filaments
-
Ledesma, M.D., Bonay, P., Colaço C., and Avila, J. (1994) Analysis of microtubule-associated protein tau glycation in paired helical filaments. J. Biol. Chem., 269:21614-21619.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21614-21619
-
-
Ledesma, M.D.1
Bonay, P.2
Colaço, C.3
Avila, J.4
-
36
-
-
0029145757
-
Isolation of phosphorylated soluble tau fraction from Alzheimer's disease brain
-
Ledesma, M.D., Avila, J., and Correas, I. (1995) Isolation of phosphorylated soluble tau fraction from Alzheimer's disease brain. Neurobiol. Aging, 16:515-522.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 515-522
-
-
Ledesma, M.D.1
Avila, J.2
Correas, I.3
-
37
-
-
0027945346
-
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filaments
-
Matsuo, E.S., Shin, R.W., Billingsley, M.L., Van de Voorde, A., O'Connor, M., Trojanowski, J.Q., and Lee, V.M.Y. (1994) Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filaments Neuron, 13:989-1002.
-
(1994)
Neuron
, vol.13
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.W.2
Billingsley, M.L.3
Van De Voorde, A.4
O'Connor, M.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
39
-
-
0026758096
-
Monoclonal antibodies with selective specificity for Alzheimer tau are directed against phosphatase-sensitive epitopes
-
Berl.
-
Mercken, M., Vandermeeren, M., Lübke, U., Six, J., Boons, J., Van de Voorde, A., Martin, J.-J., and Gheuens, J. (1992) Monoclonal antibodies with selective specificity for Alzheimer tau are directed against phosphatase-sensitive epitopes. Acta Neuropathol. (Berl.), 84:265-272.
-
(1992)
Acta Neuropathol.
, vol.84
, pp. 265-272
-
-
Mercken, M.1
Vandermeeren, M.2
Lübke, U.3
Six, J.4
Boons, J.5
Van De Voorde, A.6
Martin, J.-J.7
Gheuens, J.8
-
40
-
-
0029096258
-
Transglutaminase cross-linking of the tau protein
-
Miller, M.L., and Johnson, V.W. (1995) Transglutaminase cross-linking of the tau protein. J. Neurochem., 65:1760-1770.
-
(1995)
J. Neurochem.
, vol.65
, pp. 1760-1770
-
-
Miller, M.L.1
Johnson, V.W.2
-
41
-
-
0030700593
-
The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer disease: A commentary
-
Mirra, S.S. (1997) The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer disease: A commentary. Neurobiol. Aging, 18:91-94.
-
(1997)
Neurobiol. Aging
, vol.18
, pp. 91-94
-
-
Mirra, S.S.1
-
42
-
-
0025908356
-
The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathological assessment of Alzheimer's disease
-
Mirra, S.S., Hayman, A., Mckeek, D., Sumi, S.M., Crain, B.J., Brownlee, L.M., Vogel, F.S., Hugehes, J.P., van Belle, G., Berg, L., and Participating CERAD Neuropathologists (1991) The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathological assessment of Alzheimer's disease. Neurology, 41:479-486.
-
(1991)
Neurology
, vol.41
, pp. 479-486
-
-
Mirra, S.S.1
Hayman, A.2
Mckeek, D.3
Sumi, S.M.4
Crain, B.J.5
Brownlee, L.M.6
Vogel, F.S.7
Hugehes, J.P.8
Van Belle, G.9
Berg, L.10
-
43
-
-
0029010035
-
Hyperphosphorylation of tau in PHF
-
Morishima-Kawashima, M., Hasegawa, M., Takio, K., Suzuki, M., Yoshida, H., Watanabe, A., Titani, K., and Ihara, Y. (1995) Hyperphosphorylation of tau in PHF. Neurobiol. Aging, 16:365-380.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 365-380
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Watanabe, A.6
Titani, K.7
Ihara, Y.8
-
44
-
-
0030698871
-
Life and death of neurons in the aging brain
-
Morrison, J.H., and Hof, P. (1997) Life and death of neurons in the aging brain. Science, 278:412-419.
-
(1997)
Science
, vol.278
, pp. 412-419
-
-
Morrison, J.H.1
Hof, P.2
-
45
-
-
0023444240
-
Immunocytochemical properties of Alzheimer straight filaments
-
Perry, G., Mulvihill, P., Manetto, V., Autilio-Gambetti, L., and Gambetti, P. (1987) Immunocytochemical properties of Alzheimer straight filaments. J. Neurosci., 7:3736-3738.
-
(1987)
J. Neurosci.
, vol.7
, pp. 3736-3738
-
-
Perry, G.1
Mulvihill, P.2
Manetto, V.3
Autilio-Gambetti, L.4
Gambetti, P.5
-
46
-
-
0029114196
-
Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments
-
Schweers, O., Maldelkow, E.H., Biernat, J., and Maldelkow, E. (1995) Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments. Proc. Natl. Acad. Sci. USA, 92:8463-8467.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8463-8467
-
-
Schweers, O.1
Maldelkow, E.H.2
Biernat, J.3
Maldelkow, E.4
-
47
-
-
0018074261
-
Electron microscopic structure of the Alzheimer's neurofibrillary changes in case of atypical senile dementia
-
Berl.
-
Shibayama, H., and Kitoh, J. (1978) Electron microscopic structure of the Alzheimer's neurofibrillary changes in case of atypical senile dementia. Acta Neuropathol. (Berl.), 41:229-234.
-
(1978)
Acta Neuropathol.
, vol.41
, pp. 229-234
-
-
Shibayama, H.1
Kitoh, J.2
-
48
-
-
0029878826
-
Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease
-
Smith, M.A., Siedlak, S.L., Richey, P.L., Nagaraj, R.H., Elhammer, A., and Perry, G. (1996) Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease. Brain Res., 717:99-108.
-
(1996)
Brain Res.
, vol.717
, pp. 99-108
-
-
Smith, M.A.1
Siedlak, S.L.2
Richey, P.L.3
Nagaraj, R.H.4
Elhammer, A.5
Perry, G.6
-
49
-
-
0027939401
-
Early phosphorylation of tau in Alzheimer's disease occurs at Ser 202 and is preferentially located within neuntes
-
Su, J.H., Cummings, B.J., and Cotman, C.W. (1994) Early phosphorylation of tau in Alzheimer's disease occurs at Ser 202 and is preferentially located within neuntes. Neuroreport, 5:2358-2362.
-
(1994)
Neuroreport
, vol.5
, pp. 2358-2362
-
-
Su, J.H.1
Cummings, B.J.2
Cotman, C.W.3
-
50
-
-
0029815467
-
Glycosylation of microtubule associated protein tau: An abnormal posttranslational modification in Alzheimer's disease
-
Wang, J.Z., Grundke-Iqbal, I., and Iqbal, K. (1996) Glycosylation of microtubule associated protein tau: An abnormal posttranslational modification in Alzheimer's disease. Nat. Med., 2:871-875.
-
(1996)
Nat. Med.
, vol.2
, pp. 871-875
-
-
Wang, J.Z.1
Grundke-Iqbal, I.2
Iqbal, K.3
-
51
-
-
0027164617
-
Regionally specific loss of neurons in the aging human hippocampus
-
West, M.J. (1993) Regionally specific loss of neurons in the aging human hippocampus. Neurobiol. Aging. 14:287-293.
-
(1993)
Neurobiol. Aging
, vol.14
, pp. 287-293
-
-
West, M.J.1
-
52
-
-
0019935804
-
Plaques, tangles and dementia
-
Wilcock, G.K., and Esiri, M.M. (1982) Plaques, tangles and dementia. J. Neurol. Sci., 56:343-356.
-
(1982)
J. Neurol. Sci.
, vol.56
, pp. 343-356
-
-
Wilcock, G.K.1
Esiri, M.M.2
-
53
-
-
0028998417
-
Quantitative analysis of tau protein in paired helical filament preparations: Implications for the role of tau protein phosphorylation in PHF assembly in Alzheimer's disease
-
Wischick, C.M., Edwards, P.C., Lai, R.Y., Gertz, H.N.J., Xuereb, J.H., Paykel, E.S., Brayne, C., Huppert, F.A., Mukaeotova-Ladinska, E.B., Mena, R., Roth, M., and Harrington, C.R. (1995) Quantitative analysis of tau protein in paired helical filament preparations: Implications for the role of tau protein phosphorylation in PHF assembly in Alzheimer's disease. Neurobiol. Aging, 16:409-431.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 409-431
-
-
Wischick, C.M.1
Edwards, P.C.2
Lai, R.Y.3
Gertz, H.N.J.4
Xuereb, J.H.5
Paykel, E.S.6
Brayne, C.7
Huppert, F.A.8
Mukaeotova-Ladinska, E.B.9
Mena, R.10
Roth, M.11
Harrington, C.R.12
-
54
-
-
0021691350
-
Ultrastructure of paired helical filaments of Alzheimer neurofibrillary tangle
-
Wisniewski, H.M., Merz, P.A., and Iqbal, K. (1984) Ultrastructure of paired helical filaments of Alzheimer neurofibrillary tangle. Neuropathol. Exp. Neurol., 43:643-656.
-
(1984)
Neuropathol. Exp. Neurol.
, vol.43
, pp. 643-656
-
-
Wisniewski, H.M.1
Merz, P.A.2
Iqbal, K.3
-
55
-
-
1842685948
-
Neurofibrillary tangles of Alzheimer's disease share antigenic determinants with the axonal microtubule-associated protein tau
-
Wood, J.G., Mirra, S.S., Pollock, N.J., and Binder, L.I. (1986) Neurofibrillary tangles of Alzheimer's disease share antigenic determinants with the axonal microtubule-associated protein tau. Proc. Natl. Acad. Sci. USA, 83:4040-4043.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4040-4043
-
-
Wood, J.G.1
Mirra, S.S.2
Pollock, N.J.3
Binder, L.I.4
-
56
-
-
0019470087
-
Reappraisal of the fine structure of Alzheimer's neurofibrillary tangles
-
Berl.
-
Yagishita, S., Itoh, Y., Nan, W., and Amano, N. (1981) Reappraisal of the fine structure of Alzheimer's neurofibrillary tangles. Acta Neuropathol. (Berl.), 54:239-246.
-
(1981)
Acta Neuropathol.
, vol.54
, pp. 239-246
-
-
Yagishita, S.1
Itoh, Y.2
Nan, W.3
Amano, N.4
|