Chronic K-supplementation decreases myocardial [Na,K-ATPase] and net K-uptake capacity in rodents

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 10, 1998, Pages 2037-2046

  Bundgaard, Henning ^a   Enevoldsen, Micha Thyge ^a   Kjeldsen, Keld ^a  

^a Rigshospitalet   (Denmark)

Author keywords

3H ouabain binding; Hyperkalemia; K adaptation; K homeostasis; K supplementation; Myocardial K; Myocardial Na,K ATPase; Plasma K

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); OUABAIN; POTASSIUM; POTASSIUM CHLORIDE; POTASSIUM ION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; GUINEA PIG; HEART MUSCLE; HOMOGENATE; IMMUNOBLOTTING; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; POTASSIUM BLOOD LEVEL; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RAT; RODENT; TISSUE LEVEL;

ANIMALIA; CAVIA; CAVIA PORCELLUS; RODENTIA; STROPHANTHUS GRATUS; SUS SCROFA;

EID: 0032191689     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0764     Document Type: Article

References (50)

1. +-depleted rats. Hypertension 7: 277-286.
2. + balance during and after shortlasting ischaemia. J Mol Cell Cardiol 21: 1273-1284.
3. + repletion and rise in contractility after brief ischemic periods in the pig. J Mol Cell Cardiol 21: 681-690.
4. + influx of the in-situ beating porcine heart. Acta Physiol Scand 140: 413-418.
5. BLACHLEY JD, CRIDER BP, JOHNSON JH, 1986. Extrarenal potassium adaptation: role of skeletal muscle. Am J Physiol 251: F313-F318.
6. +-ATPase subunit isoforms at mRNA and protein levels in rat myocardium. J Mol Cell Cardiol 26: 591-600.
7. BUNDGAARD H, KJELDSEN K, 1996. Human myocardial Na,K-ATPase concentration in heart failure. Moll Cell Biochem 163/164: 277-283.
8. + homeostasis in rats. J Appl Physiol 82: 1136-1144.
9. CLAUSEN T, EVERTS ME, KJELDSEN K, 1987. Quantification of the maximum capacity for active sodium-potassium transport in rat skeletal muscle. J Physiol Lond 388: 163-181.
10. CURTIS MJ, 1991. The rabbit dual coronary perfusion model: a new method for assessing the pathological relevance of individual products of the ischaemic milieu: role of potassium in arrhythmogenesis. Cardiovasc Res 25: 1010-1022.
11. + pump current, intracellular sodium, and action potential duration in rabbit heart. Am J Physiol 268: H1838-H1846.
12. ELLINGSEN Ø, SEJERSTED OM, VENGEN ØA, ILEBEKK A, 1991. Frequency dependent myocardial potassium fluxes during β-adrenergic stimulation of intact pig hearts. Cardiovasc Res 25: 364-370.
13. ELLINGSEN Ø, HOLTHE R, SVINDLAND A, AKSNES G, SEJERSTED OM, ILEBEKK A, 1994. Na,K-pump concentration in hypertrophied human hearts. Eur Heart J 15: 1184-1190.
14. FOSTER ES, JONES WJ, HAYSLETT JP, BINDER HJ, 1988. Role of aldosterone and dietary potassium in potassium adaptation in the distal colon of the rat. Gastroenterology 88: 41-46.
15. + pump in rat cortical collecting tubules. Am J Physiol 256: 279-284.
16. GILL JRJ, SANTOS F, CHAN JCM, 1990. Disorders of potassium metabolism. In: Chan JCM and Gill JRJ (eds). Kidney Electrolyte Disorders. New York: Churchill Livingstone, 137.
17. +-ATPaSe concentration with short-term training. Am J Physiol 264: 1538-1541.
18. +-ATPase concentration in porcine skeletal muscle is markedly upregulated in late gestation. J Physiol Lond 494: 33.
19. 1-UiRNA and -protein levels at steady state. Am J Physiol 262: C484-C492.
20. 3H-ouabain binding sites in mammalian skeletal muscle. Pflügers Arch 402: 100-108.
21. 3H]ouabain distribution in the guinea pig. J Pharmacol Exp Ther 234: 720-727.
22. 3H]ouabain-binding sites and sodium and potassium contents in rat skeletal muscle. Br J Nutr 56: 519-532.
23. 2+-dependent pNPPase. Age-dependent changes. Basic Res Cardiol 90: 323-331.
24. 2+-ATPaSe in rodents with hypertrophy. Moll Cell Biochem 169: 85-93.
25. 2+ in protecting the heart from hyperkalemia and acidosis in the rabbit: implications for exercise. J Appl Physiol 77: 2391-2399.
26. LOWRY OH, ROSEBROUGH NJ, FARR AL, RANDALL RJ, 1951. Protein measurement with the folin phenol reagent. J Biol Chem 193: 265-275.
27. MAGYAR CE, JIANGNAN W, AZUMA KK, MCUONOUGH AA, 1995. Reciprocal regulation of cardiac Na,K-ATPase and Na/Ca exchanger: hypertension, thyroid hormone, development. Am J Physiol 269: C675-C682.
28. 3 subunit. J Biol Chem 271/37: 22754-22758.
29. McDoNOUGH AA, AZUMA KK, LESCALE-MATYS L, TANG M, NAKHOUL F, HENSLEY CB, KOMATSU Y, 1992. Physiological rationale for multiple sodium pump isoforms. Ann NY Acad Sci 671: 156-168.
30. + regulation. J Appl Physiol 75: 173-180.
31. NORGAARD A, KJELDSEN K, 1989. Human myocardial Na, K-pumps in relation to heart disease. J Appl Cardiol 4: 239-245.
32. + pump density. Nature 295: 717-718.
33. +-dependent 3-0-methyfluorescein phosphatase activity in crude homogenate of rodent heart ventricle: effect of K+ depletion and changes in thyroid status. Eur J Pharmacol 113: 373-382.
34. NORGAARD A, BAGGER JP, BJERREGAARD P, BAANDRUP U, KJELDSEN K, THOMSON PE, 1988. Relation of left ventricular function and Na,K-pump concentration in suspected idiopathic dilated cardiomyopathy. Am J Cardiol 61: 1312-1315.
35. PATERSON DJ, BLAKE GJ, LEITCH SP, PHILLIPS SM, BROWN HF, 1992. Effects of catecholamines and potassium on cardiovascular performance in the rabbit. J Appl Physiol 73: 1413-1418.
36. +-pumping in isolated atrial tissue from patients treated with digoxin. J Pharmacol Exp Ther 252: 60-64.
37. 3H-ouabain binding to intact myocardial samples. Stability to short term ischemia reperfusion. Basic Res Cardiol 85: 411-427.
38. +-ATPase: effect of age and potassium depletion. J Neurochem 59: 2094-2104.
39. SCHMIDT TA, ALLEN PD, COLUCCI WS, MARSH JD, KJELDSEN K, 1993. No adaptation to digitalization as evaluated by digitalis receptor (Na,K-ATPase) quantification in explanted hearts from donors without heart disease and from digitalized recipients with end-stage heart failure. Am J Cardiol 71: 110-114.
40. SCHMIDT TA, BUNDGAARD H, OLESEN HL, SECHER NH, KJELDSEN K, 1995. Digoxin affects potassium homeostasis during exercise in patients with heart failure. Cardiovasc Res 29: 506-511.
41. +-pump. Part B: Cellular aspects. New York: Alan R. Inc., 195-206.
42. 3, and β subunits of the Na,K-ATPase: differential expression of α and β subunits in rat tissue membranes. Biochemistry 28: 4531-4538.
43. SILVA P, HAYSLETT JP, EBSTEIN FH, 1973. The role of Na-K-activated adenosine triphosphatase in potassium adaptation. J Clin Invest 52: 2665-2671.
44. SPITAL A, STERNS RH, 1986. Paradoxical potassium depletion: a renal mechanism for extrarenal potassium adaptation. Kidney Int 30: 532-537.
45. STUMMER W, BETZ AL, KEEP RE, 1995. Mechanisms of brain ion homeostasis during acute and chronic variations of plasma potassium. J Cerebral Blood Flow Metab 15: 336-344.
46. +-ATPase isoforms in myocardium. Circ Res 74: 669-678.
47. THATCHER JS, RADIKE AW, 1947. Tolerance to potassium intoxication in the albino rat. Am J Physiol 151: 138-146.
48. TOSAKI A, KOLTAI M, BRAQUET P, 1989. Effects of low extracellular sodium concentration on reperfusion induced arrhythmias: changes in the myocardial sodium, potassium and calcium contents in isolated guinea pig hearts. Cardiovasc Res 23: 993-1000.
49. + pump. Am J Physiol 249: H1093-H1097.
50. WARD JPT, CAMERON IR, 1984. Adaptation of the cardiac muscle sodium pump to chronic potassium deficiency. Cardiovasc Res 18: 257-263.