Endothelin-1 in the rat bile duct ligation model of hepatopulmonary syndrome: Correlation with pulmonary dysfunction

Journal of Hepatology

Volumn 29, Issue 4, 1998, Pages 571-578

  Luo, Bao ^a   Abrams, Gary A ^a   Fallon, Michael B ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Common bile duct ligation; Endothelin 1; Hepatopulmonary syndrome; Portal hypertension

Indexed keywords

ENDOTHELIN 1; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; COMMON BILE DUCT; CONTROLLED STUDY; GAS EXCHANGE; HEPATOPULMONARY SYNDROME; IMMUNOHISTOCHEMISTRY; LIVER INJURY; LUNG ALVEOLUS OXYGEN TENSION; LUNG DISEASE; MALE; NONHUMAN; NORTHERN BLOTTING; PATHOPHYSIOLOGY; PORTAL HYPERTENSION; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 0032191669     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(98)80152-9     Document Type: Article

References (20)

1. 1. Lange PA, Stoller JK. The hepatopulmonary syndrome. Ann Intern Med 1995; 122: 521-9.
2. 2. Chang S-W, O'Hara N. Pulmonary circulatory dysfunction in rats with biliary cirrhosis. Am Rev Respir Dis 1992; 148: 798-805.
3. 3. Fallon MB, Abrams GA, McGrath JW, Hou Z, Luo B. Common bile duct ligation in the rat: a model of intrapulmonary vasodilatation and hepatopulmonary syndrome. Am J Physiol 1997; 272 (Gastrointest Liver Physiol 35): G779-84.
4. 4. Fallon MB, Abrams GA, Luo B, Hou Z, Dai J, Ku DD. The role of endothelial nitric oxide synthase in the pathogenesis of a rat model of hepatopulmonary syndrome. Gastroenterology 1997; 113: 606-14.
5. 5. Leivas A, Jimenez W, Lamas S, Bosch-Marce M, Oriola J, Claria J, et al. Endothelin 1 does not play a major role in the homeostasis of arterial pressure in cirrhotic rats with ascites. Gastroenterology 1995; 108: 1842-8.
6. 6. Asbert M, Gines A, Gines P, Jimenez W, Claria J, Salo J, et al. Circulating levels of endothelin in cirrhosis. Gastroenterology 1993; 104: 1485-91.
7. 7. Moore K, Wendon J, Frazer M, Karani J, Williams R, Badr K. Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. N Engl J Med 1992; 327: 1774-7.
8. 8. Filep JG. Endothelin peptides: biological actions and pathophysiological significance in the lung. Life Sci 1992; 52: 119-33.
9. 9. Tien-A-Looi S, Keith IM. Effects of chronic endothelin-1 infusion in the rat pulmonary circulation in normoxia and hypoxia [abstract]. FASEB J 1992; 6: 1178.
10. 10. Pinzani M, Milani S, DeFranco R, Grappone C, Caligiuri A, Gentilini A, et al. Endothelin 1 is overexpressed in human cirrhotic liver and exerts multiple effects on activated hepatic stellate cells. Gastroenterology 1996; 110: 534-48.
11. 11. Hirata Y, Emori T, Eguchi S, Kanno K, Imai T, Ohta K, et al. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest 1993; 91: 1367-71.
12. 12. Bezie Y, Mesnard L, Longrois D, Samson F, Perret C, Mercadier JJ, et al. Interactions between endothelin-1 and atrial natriuretic peptide influence cultured chick cardiac myocyte. Eur J Pharmacol 1996; 311: 241-8.
13. 13. Bruneau BG, de Bold AJ. Selective changes in natriuretic peptide and early response gene expression in isolated rat atria following stimulation by stretch or endothelin-1. Cardiovasc Res 1994; 28: 1519-25.
14. 14. Easter DW, Wade JB, Boyer JL. Structural integrity of hepatocyte tight junctions. J Cell Biol 1983; 96: 745-9.
15. 15. Chojkier M, Groszmann RJ. Measurement of portal systemic shunting using gamma-labelled microspheres. Am J Physiol 1981; 240 (Gastrointest Liver Physiol): G371-5.
16. 16. Elton TS, Oparil S, Taylor GR, Hicks PH, Yang R-H, Jin H, et al. Normobaric hypoxia stimulates endothelin-1 gene expression in the rat. Am J Physiol 1992; 263 (Regulatory Integrative Comp Physiol 32): R1260-4.
17. 17. Oparil S, Chen SJ, Meng QC, Elton TS, Yano M, Chen YF. Endothelin-A receptor antagonist prevents acute hypoxia-induced pulmonary hypertension in the rat. Am J Physiol 1995; 268 (Lung Cell Mol Physiol 1): L95-100.
18. 18. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Ann Biochem 1987; 162: 156-9.
19. 19. Tso JY, Sun XH, Kao TH, Reece KS, Wu R. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene. Nucleic Acids Res 1985; 13: 2485-502.
20. 20. Fallon MB, Brecher AR, Balda MS, Matter K, Anderson JM. Altered hepatic localization and expression of occludin after common bile duct ligation. Am J Physiol 1995; 269 (Cell Physiol 38): C1057-62.