Neurochemical variables in schizophrenic patients during switching from neuroleptics to clozapine

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 22, Issue 7, 1998, Pages 1077-1085

  Hatzimanolis, John ^a   Lykouras, Lefteris ^a   Markianos, Manolis ^a   Oulis, Panagiotis ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

3 methoxy 4 hydroxyphenylglycol; 5 hydroxyindoleacetic acid; Clozapine; Cortisol; Homovanillic acid; Prolactin; Schizophrenia

Indexed keywords

4 HYDROXY 3 METHOXYPHENYLETHYLENE GLYCOL; 5 HYDROXYINDOLEACETIC ACID; CLOZAPINE; DOPAMINE; HOMOVANILLIC ACID; HYDROCORTISONE; NEUROLEPTIC AGENT; NORADRENALIN; PROLACTIN; SEROTONIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DOPAMINE METABOLISM; DOPAMINE URINE LEVEL; DRUG EFFICACY; HUMAN; HYDROCORTISONE BLOOD LEVEL; MALE; NORADRENALIN URINE LEVEL; PROLACTIN BLOOD LEVEL; SCHIZOPHRENIA; SEROTONIN METABOLISM;

EID: 0032190821     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(98)00064-5     Document Type: Article

References (27)

1. ADDIS, T., BARRET, E., and POO, C.F. (1951) The relation between consumption and diurnal variations of the endogenous creatinine clearance in normal individuals. J. Clin. Investigation 30:206-209.
2. rd ed., Revised, APA, Washington.
3. BALDESSARINI, R., HUSTON-LYONS, D., CAMPBELL, A., MARCH, E. And COHEN, B.M. (1992) Central antiadrenergic actions contribute to the atypical properties of clozapine. Br. J. Psychiatry 160 (Suppl 17): S12-S16.
4. BARTELS, H., and BOHMER, M. (1971) Micro-determination of creatinine. Clin. Chim. Acta 32:81-85.
5. BOWERS, M.B., SWIGAR, M.E., JATLOW, P.I. and HOFFMAN, F.J. (1989) Plasma catecholamine metabolites and treatment response at neuroleptic state. Biol. Psychiatry, 25:734-738.
6. CHANG, W.H., HWU, H.G., CHEN, T.Y., LIN, S.K., LUNG, F.W., LIN, W.L., HU, W.H., LIN, H.N. and CHIEN, C.P. (1993) Plasma homovanillic acid and treatment response in a large group of schizophrenic patients. Schiz. Research 10:259-265.
7. COWARD, D.M. (1992) General pharmacology of clozapine. Br. J. Psychiatry 160 (suppl 17): S5-S11.
8. DAVIDSON, M., KAHN, R.S., KNOTT, P., KAMINSKY, R., DUMONT, K., APTER, S. and DAVIS, K.L. (1991) The effect of neuroleptic treatment on plasma homovanillic acid concentrations and schizophrenic symptoms. Arch. Gen. Psychiatry 48:73-76.
9. DAVIDSON, M., KAHN, R.S., STERN, R.G., HIRSCHOWITZ, J., APTER, S., KUOTT, P. and DAVIS, K.L. (1993) Treatment with clozapine and its effect on plasma homovanillic acid and norepinephrine concentrations in schizophrenia. Psychiat. Research 46:151-163.
10. DAVILA, R., MANERO, E., ZUMARRAGA-ANDIA, I., SCHWEITZER, J.W. and FRIENDHOFF, A.J. (1988) Plasma homovanillic acid as a predictor of response to neuroleptics. Arch. Gen. Psychiatry 45:564-567.
11. DELISI, L.E., KAROUM, F., TARGUM, S., BYRNES, S., and WYATT, R.J. (1983) The determination of urinary 3-methoxy-4-hydroxy-phenylglycol excretion in acute schizophreniform and depressed patients. Biol. Psychiatry 18:1189-1196.
12. FERNSTROM, J.D. (1976) The effect of nutritional factors on brain aminoacid levels and monoamine synthesis. Fed. Proc 35:1151-1156.
13. GREEN, A.I., ALAM, M.Y., SOBIERAJ, J.T., PAPPALARDO, K.M., WATERNAUX, C., SALZAMAN, C., SCHATZBERG, A.F., and SCHILDKRAUT, J.J. (1993) Clozapine response and plasma catecholamines and their metabolites. Psychiatry Res. 46, 139-149.
14. HARRIS, J., KRAHENBUHL, C.S., and MALCHOW, R.D. (1985) Neurochemistry of stress: urinary biogenic amine metabolite excretion rates in exercise. Biogenic Amines 2:261-269.
15. HSIAO, J.K., POTTER, W.Z., AGREN, H., OWEN, R.R., and PICKAR, D. (1993) Clinical investigation of monoamine neurotransmitter interactions. Psychopharmacology 112 (suppl): S76-S84.
16. MAAS, J.W., WARICETT, J.A., and DEKIRMENKAN, H. (1968) 3-methoxy-4-hydroxy-phenylglycol (MHPG) excretion in depressive states. Arch. Gen. Psychiatry 34:1547-1549.
17. MARKIANOS, M., BOTSIS, A., and ARVANITIS, Y. (1992) Biogenic amine metabolites in plasma of drug-naive schizophrenic patients: associations with symptomatology. Biol. Psychiatry 32:288-292.
18. MAZURE, C.M., NELSON, J.L., JATLOW, P.I., and BOWERS, M.B. (1991) Plasma free homovanillic acid (HVA) as a predictor of clinical response in acute psychosis. Biol. Psychiatry 30:475-482.
19. MELTZER, H.Y. (1989) Clinical studies in the mechanism of action of clozapine: The dopamine-serotonin hypothesis of schizophrenia. Psychopharmacology, 99 (suppl): S18-S27.
20. MELTZER, H.Y., GOODE, D.J., SCHYVE, P.M., YOUNG, M. and FANG V.S. (1979) Effect of clozapine on human serum prolactin levels. Am J Psychiatry 136:1550-1555.
21. MELTZER, H.Y., BASTANI, B., KWON, K., RAMIREZ, L., BURNETT, S. and SHARPE, j. (1989) A prospective study of clozapine in treatment-resistant schizophrenic patients. Psychopharmacology 99:568-572.
22. PICKAR, D., OWEN, R.R., LITMAN, R.E., KONICKI, E., GUTIERREZ, R., and RAPAPORT, M.H. (1992) Clinical and biologic response to clozapine in patients with schizophrenia: Crossover comparison with fluphenazine. Arch. Gen. Psychiatry 49:345-353.
23. POTTER, W.Z., KO, G.N., ZHANG, L.D., and YAN, W. (1989) Clozapine in China: A review and preview of US/PRC collaboration. Psychopharmacology 99 (suppl): S87-S91.
24. SARAFOFF, M., DAVIS, L., and RUTHER, E. (1979) Clozapine-induced increase in human plasma norepinephrine. J Neural Transmission 46:175-180.
25. SHEKIM, W.O., JAVAID, J., RUTLEDGE, M., BYLUND, D.B., and DAVIS, J.M. (1984) Factors affecting urinary excretion of 3-methoxy-4-hydroxyphenyl-glycol in children and its clinical significance. J. Am. Acad. Chil. Psychiatry 23:343-347.
26. SZYMANSKI, S., LIEBERMAN, J., POLLACK, S., MUNNE, R., SAFFERMAN, A., KANE, J., KRONIG, M., and COOPER, T. (1993) The dopamine-serotonin relationship in clozapine response. Psychopharmacology 112 (suppl): S85-S89.
27. VAN KAMMEN, KELLEY, M.E., YAO, J.K., GILBERTSON, M.W., GURKLIS, J.A., INOSAKA, T., SAITO, H. PETERS, J.L., and SATO M. (1996) Predicting haloperidol treatment response in chronic schizophrenia. Psychiat. Research 64:47-58.