메뉴 건너뛰기




Volumn 40, Issue 1, 1998, Pages 211-222

Terbutaline-induced desensitization of human cardiac β2-adrenoceptor- mediated positive inotropic effects: Attenuation by ketotifen

Author keywords

Desensitization; Human cardiac 1 adrenoceptors; Human cardiac 2 adrenoceptors; Ketotifen; Positive inotropic effect; Terbutaline

Indexed keywords

ALEUDRINA; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; KETOTIFEN; KETOTIFEN FUMARATE; TERBUTALINE; UNCLASSIFIED DRUG;

EID: 0032189920     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(98)00101-1     Document Type: Article
Times cited : (19)

References (35)
  • 1
    • 0025223081 scopus 로고
    • Turning off the signal: Desensitization of β-adrenergic receptor function
    • [1] Hausdorff WP, Caron MG, Lefkowitz RJ. Turning off the signal: desensitization of β-adrenergic receptor function. FASEB J 1990;4:2881-2889.
    • (1990) FASEB J , vol.4 , pp. 2881-2889
    • Hausdorff, W.P.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 2
    • 0027375964 scopus 로고
    • Molecular mechanisms of membrane receptor desensitization
    • [2] Lohse MJ. Molecular mechanisms of membrane receptor desensitization. Biochim Biophys Acta 1993;1179:171-188.
    • (1993) Biochim Biophys Acta , vol.1179 , pp. 171-188
    • Lohse, M.J.1
  • 3
    • 0022553339 scopus 로고
    • Adrenergic therapy of bronchial asthma
    • [3] Nelson HS. Adrenergic therapy of bronchial asthma. J Allergy Clin Immunol 1986;77:771-785.
    • (1986) J Allergy Clin Immunol , vol.77 , pp. 771-785
    • Nelson, H.S.1
  • 4
    • 0020521614 scopus 로고
    • Selective down regulation of adrenergic receptor subtypes in rats with pheochromocytoma
    • [4] Snavely MD, Mahan LC, O'Connor DT, Insel PA. Selective down regulation of adrenergic receptor subtypes in rats with pheochromocytoma. Endocrinology 1983; 113:354-361.
    • (1983) Endocrinology , vol.113 , pp. 354-361
    • Snavely, M.D.1    Mahan, L.C.2    O'Connor, D.T.3    Insel, P.A.4
  • 5
    • 0021252143 scopus 로고
    • Desensitization of beta-adrenergic receptors by pheochromocytoma
    • [5] Tsujimoto G, Manger WM, Hoffman BB. Desensitization of beta-adrenergic receptors by pheochromocytoma. Endocrinology 1984;114:1272-1278.
    • (1984) Endocrinology , vol.114 , pp. 1272-1278
    • Tsujimoto, G.1    Manger, W.M.2    Hoffman, B.B.3
  • 6
    • 0027490105 scopus 로고
    • Changes in myocardial and vascular receptors in heart failure
    • [6] Bristow MR. Changes in myocardial and vascular receptors in heart failure. J Am Coll Cardiol 1993;22(4):61A-71A.
    • (1993) J Am Coll Cardiol , vol.22 , Issue.4
    • Bristow, M.R.1
  • 7
    • 0028866483 scopus 로고
    • Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic heart failure
    • [7] Brodde O-E, Michel MC, Zerkowski H-R. Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic heart failure. Cardiovasc Res 1995;30:570-584.
    • (1995) Cardiovasc Res , vol.30 , pp. 570-584
    • Brodde, O.-E.1    Michel, M.C.2    Zerkowski, H.-R.3
  • 8
    • 0025851462 scopus 로고
    • 2-adrenoceptors in the human heart: Properties, function and alterations in chronic heart failure
    • 2-adrenoceptors in the human heart: properties, function and alterations in chronic heart failure. Pharmacol Rev 1991;43:203-242.
    • (1991) Pharmacol Rev , vol.43 , pp. 203-242
    • Brodde, O.-E.1
  • 9
    • 0023801789 scopus 로고
    • Myocardial α-and β-adrenoceptors in heart failure: Is cardiac-derived norepinephrine the regulatory signal?
    • [9] Bristow MR, Sandoval AB, Gilbert EM, et al. Myocardial α-and β-adrenoceptors in heart failure: is cardiac-derived norepinephrine the regulatory signal?. Eur Heart J 1988;9(H):35-40.
    • (1988) Eur Heart J , vol.9 , Issue.H , pp. 35-40
    • Bristow, M.R.1    Sandoval, A.B.2    Gilbert, E.M.3
  • 11
    • 0031030215 scopus 로고    scopus 로고
    • Influence of adrenoceptor and muscarinic receptor blockade on the cardiovascular effects of exogenous noradrenaline and of endogenous noradrenaline released by infused tyramine
    • [11] Schäfers RF, Poller U, Pönicke K, et al. Influence of adrenoceptor and muscarinic receptor blockade on the cardiovascular effects of exogenous noradrenaline and of endogenous noradrenaline released by infused tyramine. Naunyn-Schmiedeberg's Arch Pharmacol 1997;355:239-249.
    • (1997) Naunyn-schmiedeberg's Arch Pharmacol , vol.355 , pp. 239-249
    • Schäfers, R.F.1    Poller, U.2    Pönicke, K.3
  • 12
    • 0028174236 scopus 로고
    • Downregulation of myocardial β-adrenergic receptors. Receptor subtype selectivity
    • [12] Muntz KH, Zhao M, Miller JC. Downregulation of myocardial β-adrenergic receptors. Receptor subtype selectivity . Circ Res 1994;74:369-375.
    • (1994) Circ Res , vol.74 , pp. 369-375
    • Muntz, K.H.1    Zhao, M.2    Miller, J.C.3
  • 16
    • 0022402992 scopus 로고
    • 2-adrenoceptors. Accelerated restoration of β-adrenoceptor responsiveness by prednisolone and ketotifen
    • 2-adrenoceptors. Accelerated restoration of β-adrenoceptor responsiveness by prednisolone and ketotifen. J Clin Invest 1985;76:1096-1101.
    • (1985) J Clin Invest , vol.76 , pp. 1096-1101
    • Brodde, O.-E.1    Brinkmann, M.2    Schemuth, R.3    O'Hara, N.4    Daul, A.5
  • 18
    • 0028957667 scopus 로고
    • Systolic time intervals: A method to assess cardiovascular drug effects in humans
    • [18] Belz GG. Systolic time intervals: a method to assess cardiovascular drug effects in humans. Eur J Clin Invest 1995;25:35-41.
    • (1995) Eur J Clin Invest , vol.25 , pp. 35-41
    • Belz, G.G.1
  • 19
    • 0028966955 scopus 로고
    • The β-adrenoceptor subtypes mediating adrenaline-and dobutamine-induced blood pressure and heart rate changes in healthy volunteers
    • [19] Daul A, Hermes U, Schäfers RF, et al. The β-adrenoceptor subtypes mediating adrenaline-and dobutamine-induced blood pressure and heart rate changes in healthy volunteers. J Clin Pharmacol Ther 1995;33:140-148.
    • (1995) J Clin Pharmacol Ther , vol.33 , pp. 140-148
    • Daul, A.1    Hermes, U.2    Schäfers, R.F.3
  • 20
    • 0024380857 scopus 로고
    • In vivo studies on the function of cardiac β-adrenoceptors in man
    • [20] McDevitt DG. In vivo studies on the function of cardiac β-adrenoceptors in man. Eur Heart J 1989;10(B):22-28.
    • (1989) Eur Heart J , vol.10 , Issue.B , pp. 22-28
    • McDevitt, D.G.1
  • 21
    • 0023777796 scopus 로고
    • Beta adrenoceptor subtype binding activity in plasma and beta blockade by propranolol and beta-1 selective bisoprolol in humans. Evaluation with schild-plots
    • [21] Wellstein A, Belz GG, Palm D. Beta adrenoceptor subtype binding activity in plasma and beta blockade by propranolol and beta-1 selective bisoprolol in humans. Evaluation with Schild-plots. J Pharmacol Exp Ther 1988;246:328-337.
    • (1988) J Pharmacol Exp Ther , vol.246 , pp. 328-337
    • Wellstein, A.1    Belz, G.G.2    Palm, D.3
  • 22
    • 0022547778 scopus 로고
    • The role of cardiac beta-1 receptors in the hemodynamic response to a beta-2 agonist
    • [22] Strauss MH, Reeves RA, Smith DL, Leenen FHH. The role of cardiac beta-1 receptors in the hemodynamic response to a beta-2 agonist. Clin Pharmacol Ther 1986;40:108-115.
    • (1986) Clin Pharmacol Ther , vol.40 , pp. 108-115
    • Strauss, M.H.1    Reeves, R.A.2    Smith, D.L.3    Leenen, F.H.H.4
  • 26
    • 0025342212 scopus 로고
    • 2-adrenoceptor-mediated physiological effects by xamoterol or procaterol
    • 2-adrenoceptor-mediated physiological effects by xamoterol or procaterol. Circulation 1990;81:914-921.
    • (1990) Circulation , vol.81 , pp. 914-921
    • Brodde, O.-E.1    Daul, A.2    Michel-Reher, M.3
  • 27
    • 0027254882 scopus 로고
    • Long-term exposure to beta 2-receptor agonist specifically desensitizes beta-receptor-mediated venodilation
    • [27] Stein M, Deegan R, Wood AJ. Long-term exposure to beta 2-receptor agonist specifically desensitizes beta-receptor-mediated venodilation. Clin Pharmacol Ther 1993;54:187-193.
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 187-193
    • Stein, M.1    Deegan, R.2    Wood, A.J.3
  • 28
    • 0020676571 scopus 로고
    • β-adrenergic tachyphylaxis in the rat and its reversal and prevention by ketotifen
    • [28] Bretz U, Martin U, Mazzoni L, Ney UM. β-Adrenergic tachyphylaxis in the rat and its reversal and prevention by ketotifen. Eur J Pharmacol 1983;86:321-328.
    • (1983) Eur J Pharmacol , vol.86 , pp. 321-328
    • Bretz, U.1    Martin, U.2    Mazzoni, L.3    Ney, U.M.4
  • 29
    • 0023908837 scopus 로고
    • Effects of the antiallergic drug ketotifen on bronchial resistance and β-adrenoceptor density of lymphocytes in children with exercise-induced asthma
    • [29] Reinhardt D, Ludwig J, Braun D, Kusenbach G, Griese M. Effects of the antiallergic drug ketotifen on bronchial resistance and β-adrenoceptor density of lymphocytes in children with exercise-induced asthma. Dev Pharmacol Ther 1988;11:180-188.
    • (1988) Dev Pharmacol Ther , vol.11 , pp. 180-188
    • Reinhardt, D.1    Ludwig, J.2    Braun, D.3    Kusenbach, G.4    Griese, M.5
  • 30
    • 0023901637 scopus 로고
    • The effect of ketotifen on bronchial beta-adrenergic tachyphylaxis in normal human volunteers
    • [30] Pauwels R, Van der Straeten M. The effect of ketotifen on bronchial beta-adrenergic tachyphylaxis in normal human volunteers. J Allergy Clin Immunol 1988;81:674-680.
    • (1988) J Allergy Clin Immunol , vol.81 , pp. 674-680
    • Pauwels, R.1    Van Der Straeten, M.2
  • 32
    • 0022196924 scopus 로고
    • 2-adrenoceptor antagonist ICI 118,551 on exercise tachycardia and isoprenaline-induced β-adrenoceptor responses in man
    • 2-adrenoceptor antagonist ICI 118,551 on exercise tachycardia and isoprenaline-induced β-adrenoceptor responses in man. Br J Clin Pharmacol 1985;19:619-630.
    • (1985) Br J Clin Pharmacol , vol.19 , pp. 619-630
    • Arnold, J.M.O.1    O'Connnor, P.C.2    Riddell, J.G.3
  • 35
    • 0025237868 scopus 로고
    • On the physiologic role of beta-2 adrenoceptors in the human heart: In vitro and in vivo studies
    • [35] Motomura S, Zerkowski H-R, Daul A, Brodde O-E. On the physiologic role of beta-2 adrenoceptors in the human heart: in vitro and in vivo studies. Am Heart J 1990;119:608-619.
    • (1990) Am Heart J , vol.119 , pp. 608-619
    • Motomura, S.1    Zerkowski, H.-R.2    Daul, A.3    Brodde, O.-E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.