Glial contribution to glutamate uptake at Schaffer collateral- commissural synapses in the hippocampus

Journal of Neuroscience

Volumn 18, Issue 19, 1998, Pages 7709-7716

  Bergles, Dwight E ^a   Jahr, Craig E ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Astrocyte; CA1; EAAC1; GLAST; GLT 1; Glutamate transporter; Hippocampus

Indexed keywords

GLUTAMIC ACID;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; ASTROCYTE; CHANNEL GATING; CONTROLLED STUDY; HIPPOCAMPUS; MALE; MEMBRANE CURRENT; NONHUMAN; PRIORITY JOURNAL; RAT; STEADY STATE; SYNAPSE; TEMPERATURE DEPENDENCE;

EID: 0032189544     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-19-07709.1998     Document Type: Article

References (10)

1. Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, Amara SG (1994) Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14:5559-5569.
2. Asztely F, Erdemli G, Kullmann DM (1997) Extrasynaptic glutamate spillover in the hippocampus: dependence on temperature and the role of active glutamate uptake. Neuron 18:281-293.
3. Attwell D, Barbour B, Szatkowski M (1993) Nonvesicular release of neurotransmitter. Neuron 11:401-407.
4. Barbour B, Hausser M (1997) Intersynaptic diffusion of neurotransmitter. Trends Neurosci 20:377-384.
5. Bergles DE, Jahr CE (1997) Synaptic activation of glutamate transporters in hippocampal astrocytes. Neuron 19:1297-1308.
6. Bergles DE, Dzubay J, Jahr CE (1997) Glutamate transporter currents in Bergmann glial cells follow the time course of extrasynaptic glutamate. Proc Natl Acad Sci USA 94:14821-14825.
7. Chaudhry FA, Lehre KP, van Lookeren Campagne M, Ottersen OP, Danbolt NC, Storm-Mathisen J (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15:711-720.
8. Linden DJ (1997) Long-term potentiation of glial synaptic currents in cerebellar culture. Neuron 18:983-994.
9. Mennerick S, Zorumski CF (1994) Glial contribution to excitatory transmission in cultured hippocampal cells. Nature 368:59-62.
10. Mennerick S, Dhond RP, Benz A, Xu W, Rothstein JD, Danbolt NC, Isenberg KE, Zorumski CF (1998) Neuronal expression of GLT-1 glutamate transporter in hippocampal cultures. J Neurosci 15:4490-4499.