A tachykinin NK1 receptor antagonist, CP-122,721-1, attenuates kainic acid-induced seizure activity

Molecular Brain Research

Volumn 60, Issue 2, 1998, Pages 291-295

  Zachrisson, Olof ^a   Lindefors, Nils ^a   Brené, Stefan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Excitotoxicity; Kainic acid; Rat; Seizure; Substance P

Indexed keywords

CP 122721 1; KAINIC ACID; SUBSTANCE P; TACHYKININ RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; 3 (2 METHOXY 5 TRIFLUOROMETHOXYBENZYLAMINO) 2 PHENYLPIPERIDINE; MESSENGER RNA; NEUROKININ 1 RECEPTOR; PIPERIDINE DERIVATIVE; PREPROTACHYKININ; PROTEIN PRECURSOR; TACHYKININ;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; HIPPOCAMPUS; IN SITU HYBRIDIZATION; MALE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT; SEIZURE; ANIMAL; BIOSYNTHESIS; CELL SURVIVAL; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; KINETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; CELL SURVIVAL; CORPUS STRIATUM; HIPPOCAMPUS; KAINIC ACID; KINETICS; MALE; PIPERIDINES; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-1; RNA, MESSENGER; SEIZURES; SUBSTANCE P; TACHYKININS; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 0032185613     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00191-0     Document Type: Article

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