Porphyromonas gingivalis lipopolysaccharide modulates the responsiveness of human periodontal ligament fibroblasts to platelet-derived growth factor

Journal of Periodontal Research

Volumn 33, Issue 7, 1998, Pages 400-407

  Takemura, Akane ^a,b   Matsuda, Naoki ^c   Kimura, Shigenobu ^a   Fujiwara, Taku ^a   Nakagawa, Ichiro ^a   Hamada, Shigeyuki ^a  

^a OSAKA UNIVERSITY   (Japan)

^b Sunstar Inc   (Japan)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

Fibroblast; Lipopolysaccharide; Periodontal ligament; Platelet derived growth factor; Porphyromonas gingivalis

Indexed keywords

LIPOPOLYSACCHARIDE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PLATELET-DERIVED GROWTH FACTOR BB; RECOMBINANT PROTEIN;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CHEMISTRY; CYTOLOGY; DOWN REGULATION; DRUG EFFECT; FIBROBLAST; FLOW CYTOMETRY; HUMAN; METABOLISM; PERIODONTAL LIGAMENT; PORPHYROMONAS GINGIVALIS; PROTEIN BINDING; SERODIAGNOSIS;

CELL DIVISION; CELLS, CULTURED; DOWN-REGULATION; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; LIPOPOLYSACCHARIDES; PERIODONTAL LIGAMENT; PLATELET-DERIVED GROWTH FACTOR; PORPHYROMONAS GINGIVALIS; PRECIPITIN TESTS; PROTEIN BINDING; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT PROTEINS;

EID: 0032174940     PISSN: 00223484     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0765.1998.tb02336.x     Document Type: Article

References (38)

1. Deguchi S, Hori T, Creamer H, Gabler W. Neutrophil-mediated damage to human periodontal ligament-derived fibroblasts: role of lipopolysaccharide J Periodont Res 1990; 25: 293-299.
2. Sorsa T, Ingman T, Suomalainen K, et al. Identification of proteases from periodontopathogenic bacteria as activators of latent human neutrophil and fibroblast-type interstitial collagenases. Infect Immun 1992; 60: 4491 4495.
3. Gemmell E, Seymour GJ. Interleukin 1, interleukin 6 and transforming growth factor-β production by human gingival mononuclear cells following stimulation with Porphyromonas gingivalis and Fusobacterium nucleatum. J Periodont Res 1993; 28: 122-129.
4. Hamada S, Takada H, Ogawa T, Fujiwara T, Mihara J. Lipopolysaccharides of oral anaerobes associated with chronic inflammation: chemical and immunomodulating properties. Int Rev Immunol 1990; 6: 247-261.
5. Hamada S, Fujiwara T, Morishima S, et al. Molecular and immunological characterization of the fimbriae of Porphyromonas gingivalis. Microbiol Immunol 1994; 38: 921-930.
6. Agarwal S, Baran C, Piesco NP, et al. Synthesis of proinflammatory cytokines by human gingival fibroblasts in response to lipopolysaccharides and interleukin-1β. J Periodont Res 1995; 30: 382-389.
7. Takada H, Mihara J, Morisaki I, Hamada S. Induction of Interleukin-1 and -6 in human gingival fibroblast cultures stimulated with Bacteroides lipopolysaccharides. Infect Immun 1991, 59: 295-301.
8. Tamura M, Tokuda M, Nagaoka S, Takada H. Lipopolysaccharides of Bacteroides intermedius (Prevotella intermedia) and Bacteroides (Porphyromonas) gingivalis induce interleukin-8 gene expression in human gingival fibroblast cultures. Infect Immun 1992; 60: 4932-4937.
9. Yamazaki K, Ikarashi F, Aoyagi T, et al. Direct and indirect effects of Porphyromonas gingivalis lipopolysaccharide on interleukin-6 production by human gingival fibroblasts. Oral Microbiol Immunol 1992; 7: 218-224.
10. Yamaji Y, Kubota T, Sasaguri K, et al. Inflammatory cytokine gene expression in human periodontal ligament fibroblasts stimulated with bacterial lipopolysaccharides. Infect Immun 1995; 63: 3576-3581.
11. Hanazawa S, Hirose K, Ohmori Y, Amano S, Kitano S. Bacteroides gingivalis fimbriae stimulate production of thymocyte-activating factor by human gingival fibroblasts. Infect Immun 1988; 56: 272-274.
12. Olson RH, Adams DF, Layman DL. Inhibitory effect of periodontally diseased root extracts on the growth of human gingival fibroblasts. J Periodontol 1985; 56: 592-596.
13. Maidwell-Smith M, Wilson M, Kieser JB. Lipopolysaccharide (endotoxin) from individual periodontally involved teeth. J Clin Periodontol 1987; 14: 453-456.
14. Hughes FJ, Auger DW, Smales FC. Investigation of the distribution of cementum-associated lipopolysaccharides in periodontal disease by scanning electron microscope immunohistochemistry. J Periodont Res 1988; 23: 100-106.
15. Smart GJ, Wilson M, Davies EH, Kieser JB. The assessment of ultrasonic root surface debridement by determination of residual endotoxin levels. J Clin Periodontol 1990; 17: 174-178.
16. Layman DL, Diedrich DL. Growth inhibitory effects of endotoxins from Bacteroides gingivalis and intermedius on human gingival fibroblasts in vitro. J Periodontol 1987; 58: 387- 392.
17. Larjava H, Uitto V-J, Eerola E, Haapasalo M. Inhibition of gingival fibroblast growth by Bacteroides gingivalis. Infect Immun 1987; 55: 201-205.
18. Matsuda N, Lin W-L, Kumar NM, Cho MI, Genco RJ. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro J Periodontol 1992; 63: 515-525.
19. Oates TW, Rouse CA, Cochran DL. Mitogenic effects of growth factors on human periodontal ligament cells in vitro. J Periodontol 1993; 64: 142-148.
20. Lynch SE, de Castilla GR, Williams RC, et al. The effects of short-term application of a combination of platelet-derived and insulin-like growth factors on periodontal wound healing. J Periodontol 1991; 62: 458-467.
21. Wang H-L, Pappert TD, Castelli WA, Chiego Jr. DJ, Shyr Y, Smith BA. The effect of platelet-derived growth factor on the cellular response of the periodontium: an autoradiographic study on dogs. J Periodontol 1994; 65: 429-436.
22. Rutherford RB, Niekrash CE, Kennedy JE, Charette MF. Platelet-derived and insulin-like growth factors stimulate regeneration of periodontal attachment in monkeys. J Periodont Res 1992; 27: 285-290.
23. Bartold PM, Narayanan AS, Page RC. Platelet-derived growth factor reduces the inhibitory effects of lipopolysaccharide on gingival fibroblast proliferation. J Periodont Res 1992; 27: 499-505.
24. Fujiwara T, Ogawa T, Sobue S, Hamada S. Chemical, immunobiological and antigenic characterizations of lipopolysaccharides from Bacteroides gingivalis strains. J Gen Microbiol 1990; 136: 319-326.
25. Matsuda N, Kumar NM, Ramakrishnan PR, Lin W-L, Genco RJ, Cho M-I. Evidence for up-regulation of epidermal growth-factor receptors on rat periodontal ligament fibroblastic cells associated with stabilization of phenotype in vitro. Arch Oral Biol 1993; 38: 559-569.
26. Oates TW, Kose KN, Xie JF, Graves DT, Collins JM, Cochran DL. Receptor binding of PDGF-AA and PDGF-BB, and the modulation of PDGF receptors by TGF-β, in human periodontal ligament cells. J Cell Physiol 1995; 162: 359-366.
27. Cho M-I, Matsuda N, Ramakrishnan PR, Lin W-L, Genco RJ. Differential regulation of periodontal ligament cell activities by platelet-derived growth factor, insulin-like growth factor I, and epidermal growth factor. In: Genco R, Hamada S, Lehner T, McGhee J, Mergenhagen S, eds. Molecular pathogenesis of periodontal disease. Washington, DC: ASM Press, 1994: 403-414.
28. Hamada S, Takada H, Mihara J, Nakagawa I, Fujiwara T. LPS of oral Bacteroides species: general properties and induction of cytokines in human gingival fibroblast cultures. In: Nowotny A, Spitzer JJ, Ziegler EJ, eds. Cellular and molecular aspects of endotoxin reactions. Amsterdam: Elsevier Science Publishers BV, 1991: 285-294.
29. Hill SJ, Ebersole JL. The effect of lipopolysaccharide on growth factor-induced mitogenesis in human gingival fibroblasts. J Periodontol 1996; 67: 1274-1280.
30. Vaheri A, Rouslahti E, Sarvas M, Nurminen M. Mitogenic effect by lipopolysaccharide and pokeweed lectin on density-inhibited chick embryo fibroblasts. J Exp Med 1973; 138: 1356-1364.
31. Smith GL. Synergistic action of bacterial lipopolysaccharide on serum-stimulated DNA synthesis in mouse embryo fibroblasts. Proc Soc Exp Biol Med 1976; 153: 187-192.
32. Hart CE, Bowen-Pope DF. Platelet-derived growth factor receptor: current views of the two-subunit model. J Invest Dermatol 1990; 94 (suppl): 53S-57S.
33. Seifert RA, Hart CE, Phillips PE, et al. Two different subunits associate to create isoform-specific platelet-derived growth factor receptors. J Biol Chem 1989; 264: 8771-8778.
34. Heldin C-H, Backstrom G, Ostman A, et al Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types. EMBO J 1988; 7: 1387-1393.
35. Claesson-Welsh L, IIammacher A, Westermark B, Heldin C-H, Nister M. Identification and structural analysis of the A type receptor for platelet-derived growth factor. J Biol Chem 1989; 264: 1742-1747.
36. Hart CE, Seifert RA, Ross R, Bowen-Pope DF. Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody. J Biol Chem 1987; 262: 10780-10785.
37. Keating MT, Harryman CC, Williams LT. Platelet-derived growth factor receptor inducibility is acquired immediately after translation and does not require glycosylation. J Biol Chem 1989; 264: 9129-9132.
38. Colin PG, Lindroos PM, Bird GS, Osornio-Vargas AR, Roggli VL, Bonner JC. Lipopolysaccharide up-regulates platelet-derived growth factor (PDGF) α-receptor expression in rat lung myofibroblasts and enhances response to all PDGF isoforms. J Immunol 1996; 156: 4797-4806.