Antioxidative activities of 4-hydroxy-3(2H)-furanones and their anti-cataract effect on spontaneous cataract rat (ICR/f)

Bioscience, Biotechnology and Biochemistry

Volumn 62, Issue 10, 1998, Pages 1865-1869

  Sasaki, Tsutomu ^a   Yamakoshi, Jun ^a   Saito, Makoto ^a   Kasai, Kouichi ^a   Matsudo, Takanao ^a   Koga, Takuro ^a,b,c  

^a KIKKOMAN CORPORATION   (Japan)

^b Institute for Scientific Research   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Anti cataract; Antioxidant; Furanone; ICR; Spontaneous cataract rat

Indexed keywords

4 HYDROXY 2 ETHYL 5 METHYL 3(2H) FURANONE; 4-HYDROXY-2-ETHYL-5-METHYL-3(2H)-FURANONE; ANTIOXIDANT; FURAN DERIVATIVE; FURANEOL;

ANIMAL; ARTICLE; BLOOD; CATARACT; DRUG EFFECT; HUMAN; LIPID PEROXIDATION; MALE; RAT; RAT STRAIN;

ANIMALS; ANTIOXIDANTS; CATARACT; FURANS; HUMANS; LIPID PEROXIDATION; MALE; RATS; RATS, INBRED STRAINS;

EID: 0032174589     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.62.1865     Document Type: Article

References (20)

1. Sasaki, K., Hockwin, O., and Leske, M. C., Epidemiology of cataract. Dev. Ophthalmol, 15, 1-103 (1987).
2. Spector, A., Oxidation and aspects of ocular pathology. CL AO Journal, 16, 8-10 (1992).
3. Lou, M. F., Dickerson, J. E., and Garadi, R., The role of pro-tein-thiol mixed disulfides in cataractogenesis. Exp. Eye. Res., 50, 819-826 (1990).
4. Jacques, P. F., Hartz, P. F., Chylack, J. T., Jr., McGandy, R. B., and Sadowski, J. A., Nutritional status in persons with and without senile cataract: blood vitamin and mineral levels. Am. J. Clin. Nutr., 48, 152-158 (1988).
5. Robertson, J. M., Donn, A. P., and Trevithick, J. R., Vitamin E intake and risk of cataracts in humans. Ann. N. Y. Acad. Sci., 570, 372-382 (1989).
6. Nunomura, N., Sasaki, M., Asao, Y., and Yokotsuka, T., Isolation and identification of 4-hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2iT)-furanone. Agric. Biol. Chem., 40, 491-495 (1976).
7. Nagahara, A., Benjamin, H., Storkson, J., Krewson, J., Sheng, K., Liu, W., and Pariza, M. W., Inhibition of benzo[a]pyrene-in-duced mouse forestomach neoplasia by principal flavor component of Japanese-style fermented soy sauce. Cancer Research, 52, 1754-1756 (1992).
8. Rodin, J. O., Himel, C. M., Silverstein, R. M., Leeper, R. W., and Gortner, W. A., Volatile flavor and aroma components of pineapple. I. Isolation and tentative identification of 2,5-dimethyl-4-hydroxy-3(2H)-furanone. J. Food Sci., 30, 280-285 (1965).
9. 2 concentration in human polymorphonuclear leucocytes by flavour components of Japanese-style fermented soy sauce. Food and Chemical Toxicology, 35, 449-457 (1997).
10. Tsen, C. C., An improved spectrophotometoric method for the determination of tocopherols using 4-7-diphenyl-l, 10-phenan-thoroline. Anal. Chem., 33, 849-851 (1961).
11. Koga, T., Moro, K., and Matsudo, T., Antioxidative behaviors of 4-hydroxy-2,5-dimethyl-3(2if)-furanone and 4-hydroxy-2(or 5)-ethyl-5(or 2)-methyl-3(2/f)-furanone against lipid peroxidation. J. Agric. Food Chem., 46, 946-951 (1998).
12. Peer, H.G., Van Den Ouweland, G. A. M., and De Groot, C. N., The reaction of aldopentoses and secondary amine salts, a convenient method of preparing 4-hydroxy-5-methyl-2,3-di-hydrofuranone-3-one. Reel. Teav. Chim. Pays-Bas, 87, 1011 (1968).
13. Arai, H., Terao, J., Abdalla, D. S.P., Suzuki, T., and Takama, K., Coulometric detection in high-performance liquid chromatographic analysis of cholesteryl ester hydroperoxides. Free Rad. Biol. Med., 20, 365-371 (1997).
14. Hattori, H., Majima, Y., Nagamura, Y., and Ishiguro, I., Effect of vitamin E-containing liposome on experimental cataract. Nihon Ganka Gakkaishi (in Japanese), 93, 97-102 (1989).
15. Nishida, S., Mizuno, K., Matsubara, A., Asano, K., Kurono, M., and Ihara, N., Cataract development in hereditary cataract (ICR/1 strain) rat. Atarashii Ganka (in Japanese), 2, 1307-1312 (1985).
16. Re, L., and Ohloflf, G., U.S. Patent 3576014 (Apr. 20, 1971).
17. Gotoh, N., Noguchi, N., Tsuchiya, J., Morita, K., Sakai, H., Shimasaki, H., and Niki, E., Inhibition of oxidation of low density lipoprotein by vitamin E and related compounds. Free Rad. Res., 24, 123-134 (1996).
18. Yagi, K., Komura, S., Ihara, N., Abe, H., Konishi, H., and Arichi, S., Serum lipid peroxide levels in rats with inherited cataracts. J. Applied Biochem., 7, 202-206 (1985).
19. Mizuno, A., Kanematsu, E. H., Suzuki, H., and Ihara, N., Laser raman spectroscopic study of hereditary cataractous lenses in ICR/f-strain rat. Jpn. J. Ophthalmol., 32, 281-287 (1988).
20. Yagi, K., Komura, S., Yamauchi, T., Watanabe, I., and Ihara, N., Lipid peroxides as a possible cause of cataractogenesis. Proc. Int. Soc. for Eye Research, 4, 74 (1986).