Transprotection in solid phase peptide synthesis: Easy conversion of Fmoc carbamates into Boc carbamates

Tetrahedron Letters

Volumn 39, Issue 36, 1998, Pages 6421-6422

  Furlán, Ricardo L E ^a   Mata, Ernesto G ^a  

^a Universidad Nacional de Rosario   (Argentina)

Author keywords

Amino acids and derivatives; Peptides and polypeptides; Soild phase synthesis

Indexed keywords

CARBAMIC ACID DERIVATIVE; DIPEPTIDE; N FLUORENYLMETHOXYCARBONYLCARBAMIC ACID DERIVATIVE; N TERT BUTOXYCARBONYLCARBAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG TRANSFORMATION; PEPTIDE SYNTHESIS;

EID: 0032171499     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01350-1     Document Type: Article

References (7)

1. [1] Williams PL, Albericio F, Giralt E. Chemical Approaches to the Synthesis of Peptides and Proteins. CRC Press: Boca Raton, 1997.
2. [2] Merrifield RB. Science 1986;232:341-347.
3. [3] Beyermann M, Bienert M. Tetrahedron Lett. 1992;33:3745-3748.
4. [4] Furlán RLE, Mata EG, Mascaretti OA. J. Chem. Soc., Perkin Trans. 1 1998;355-358.
5. [5] Furlán RLE, Mata EG, Mascaretti OA. Peña C, Coba MP. submitted.
6. [6] For exchange of Fmoc carbamates to Boc carbamates in solution phase, see: Li W-R, Jiang J, Joullié MM. Tetrahedron Lett. 1993;34:1413-1414.
7. [7] Nagasawa T, Kuroiwa K, Narita K, Isowa Y. Bull. Chem. Soc. Jpn. 1973;46:1269-1272.