The vitamin D receptor gene and calcium metabolism

Trends in Endocrinology and Metabolism

Volumn 9, Issue 7, 1998, Pages 259-265

  Ferrari, Serge ^a   Bonjour, Jean Philippe ^a   Rizzoli, René ^a  

^a WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; VITAMIN D RECEPTOR;

BONE GROWTH; BONE MASS; BONE MINERAL; CALCIUM INTAKE; CALCIUM METABOLISM; GENE EXPRESSION; GENETIC POLYMORPHISM; HERITABILITY; HUMAN; OSTEOPOROSIS; PATHOPHYSIOLOGY; PHOSPHATE METABOLISM; PRIORITY JOURNAL; RECEPTOR GENE; REVIEW; VITAMIN D METABOLISM;

EID: 0032171294     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(98)00065-4     Document Type: Review

References (52)

1. Arai H, Miyamoto KI, Taketani Yet al. A vitamin D receptor gene polymorphism in the translation initiation codon: effect on protein activity and relation to bone mineral density in Japanese women. J Bone Miner Res. 12:1997;915-921.
2. Bonjour JP, Carrié AL, Ferrari Set al. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial. J Clin Invest. 99:1997;1287-1297.
3. Carlberg C, Bendik I, Wyss Aet al. Two nuclear signalling pathways for vitamin D. Nature. 361:1993;657-660.
4. Carling T, Kindmark A, Hellman Pet al. Vitamin D receptor genotypes in primary hyperparathyroidism. Nat Med. 1:1995;1309-1311.
5. Chapuy MC, Arlot ME, Duboeuf Fet al. Vitamin D3 and calcium to prevent hip fractures in elderly women. New Engl J Med. 327:1992;1637-1642.
6. Chevalley T, Rizzoli R, Nydegger Vet al. Effect of calcium supplements on femoral bone density and vertebral fracture rate in vitamin D-replete elderly patients. Osteoporos Int. 4:1994;245-252.
7. 3. Biochem. J 316:1996;361-371.
8. Cooper GS, Umbach DM Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis. J Bone Miner Res. 11:1996;1841-1849.
9. Dawson-Hughes B, Harris SS, Finneran S Calcium absorption on high and low calcium intakes in relation to vitamin D receptor genotype. J Clin Endocrinol Metab. 80:1995;3657-3661.
10. Dawson-Hughes B, Harris SS, Krall EA, Dallal GE Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. New Engl J Med. 337:1997;670-676.
11. Eccleshall TR, Garnero P, Gross C, Delmas P, Feldman D Lack of correlation between start codon polymorphism of the vitamin D receptor gene and bone mineral density in premenopausal French women: the OFELY study. J Bone Miner Res. 13:1998;31-35.
12. Econs MJ, Speer MC Genetic studies of complex diseases: let the reader beware. J Bone Miner Res. 11:1996;1835-1840.
13. Eisman J Vitamin D receptor gene alleles and osteoporosis: an affirmative view. J Bone Miner Res. 10:1995;1289-1293.
14. Ferrari S, Rizzoli R, Chevalley T, Slosman D, Eisman JA, Bonjour JP Vitamin-D-receptor-gene polymorphisms and change in lumbar-spine bone mineral density. Lancet. 345:1995;423-424.
15. Ferrari S, Rizzoli R, Eisman JA, Bonjour JP Relationship between vitamin D-receptor gene polymorphisms and calcium and phosphate metabolism in young healthy males. J Bone Miner Res. 11(Supp 1):1996;S209.
16. Ferrari S, Rizzoli R, Manen D, Slosman D, Bonjour JP Vitamin D receptor gene start codon polymorphisms (Fok 1) and bone mineral density: interaction with age, dietary calcium and 3′-end region polymorphisms. J Bone Miner Res. 13:1998;925-930.
17. Ferrari S, Rizzoli R, Slosman D, Bonjour JP Familial resemblance for bone mineral mass is expressed before puberty. J Clin Endocrinol Metab. 83:1998;358-361.
18. Ferrari S, Rizzoli R, Slosman D, Bonjour JP Do dietary calcium and age explain the controversy surrounding the relationship between bone mineral density and vitamin D receptor gene polymorphisms? J Bone Miner Res. 13:1998;363-370.
19. Fleet JC, Harris SS, Wook RJ, Dawson-Hughes B The BsmI vitamin D receptor restriction fragment length polymorphism (BB) predicts low bone density in premenopausal black and white women. J Bone Miner Res. 10:1995;985-990.
20. Garnero P, Borel O, Sornay-Rendu E, Delmas PD Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women. J Bone Miner Res. 10:1995;1283-1288.
21. Garnero P, Borel O, Sornay-Rendu E, Arlot ME, Delmas PD Vitamin D receptor gene polymorphisms are not related to bone turnover, rate of bone loss, and bone mass in postmenopausal women: the OFELY study. J Bone Miner Res. 11:1996;827-834.
22. Graafmans WC, Lips P, Ooms ME, van Leeuwan JPTM, Pols HAP, Uitterlinden AG The effect of vitamin D supplementation on the bone mineral density of the femoral neck is associated with vitamin D receptor genotype. J Bone Miner Res. 12:1997;1241-1245.
23. Gross C, Eccleshall TR, Malloy PJ, Villa ML, Marcus R, Feldman D The presence of a polymorphism at the translation initiation site of the vitamin D receptor gene is associated with low bone mineral density in postmenopausal Mexican-American women. J Bone Miner Res. 11:1996;1850-1855.
24. Harris SS, Eccleshall TR, Gross C, Dawson-Hughes B, Feldman D The vitamin D receptor start codon polymorphism (FokI) and bone mineral density in premenopausal American black and white women. J Bone Miner Res. 12:1997;1043-1048.
25. Haussler MR, Haussler CA, Jurutka PWet al. The vitamin D hormone and its nuclear receptor: molecular actions and disease states. J Endocrinol. 154:1997;S57-S73.
26. Housman G Human DNA polymorphism. New Engl J Med. 332:1995;318-320.
27. Houston LA, Grant SFA, Reid DM, Ralston SH Vitamin D receptor polymorphism, bone mineral density, and osteoporotic vertebral fracture: studies in a UK population. Bone. 18:1996;249-252.
28. Hustmyer FG, Peacock M, Hui S, Johnston CC, Christian J Bone mineral density in relation to polymorphism at the vitamin D receptor gene locus. J Clin Invest. 94:1994;2130-2134.
29. Johnston CC, Miller JZ, Slemenda CWet al. Calcium supplementation and increases in bone mineral density in children. New Engl J Med. 327:1992;82-87.
30. Jørgensen HL, Schøller J, Sand JC, Bjuring M, Hassager C, Christiansen C Relation of common allelic variation at vitamin D receptor locus to bone mineral density and postmenopausal bone loss: cross sectional and longitudinal population study. Br Med. J 313:1996;586-590.
31. Kanis J Calcium nutrition and its implications for osteoporosis. Part I. Children and healthy adults. Eur J Clin Nutr 48:757-767. Part II. After menopause. Eur J Clin Nutr. 48:1994;833-841.
32. Kelly PJ, Eisman JA, Sambrook PN Interaction of genetic and environmental influences on peak bone density. Osteoporos Int. 1:1990;56-60.
33. Kelly PJ, Morrison NA, Sambrook PN, Nguyen TV, Eisman JA Genetic influences on bone turnover, bone density and fracture. Eur J Endocrinol. 133:1995;265-271.
34. Kiel DP, Myers RH, Cupples Aet al. The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral density. J Bone Miner Res. 12:1997;1049-1057.
35. Kinyamu HK, Gallagher JC, Knezetic JA, DeLuca HF, Prahl JM, Lanspa SJ Effect of vitamin D receptor genotypes on calcium absorption, duodenal vitamin D receptor concentration, and serum 1,25 dihydroxyvitamin D levels in normal women. Calcif Tissue Int. 60:1997;491-495.
36. Krall EA, Parry P, Lichter JB, Dawson-Hughes B Vitamin D receptor alleles and rates of bone loss: influences of years since menopause and calcium intake. J Bone Miner Res. 10:1995;978-984.
37. McClure L, Eccleshall TR, Gross Cet al. Vitamin D receptor polymorphisms, bone mineral density, and bone metabolism in postmenopausal Mexican-American women. J Bone Miner Res. 12:1997;234-240.
38. Mocharla H, Butch AW, Pappas AAet al. Quantification of vitamin D receptor mRNA by competitive polymerase chain reaction in PBMC: lack of correspondence with common allelic variants. J Bone Miner Res. 12:1997;726-733.
39. Morrison NA, Yeoman R, Kelly PJ, Eisman JA Contribution of trans-acting factor alleles to normal physiological variability: vitamin D receptor gene polymorphism and circulating osteocalcin. Proc Natl Acad Sci USA. 89:1992;6665-6669.
40. Morrison NA, Qi JC, Tokita Aet al. Prediction of bone density from vitamin D receptor alleles. Nature. 367:1994;284-287.
41. Peacock M Vitamin D receptor gene alleles and osteoporosis: a contrasting view. J Bone Miner Res. 10:1995;1294-1297.
42. Reichel H, Koeffler HP, Norman AW The role of the vitamin D endocrine system in health and disease. New Engl J Med. 320:1989;980-991.
43. Riggs BL, Nguyen TV, Melton III LJet al. The contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women. J Bone Miner Res. 10:1995;991-996.
44. 3. Am J Physiol. 233:1977;E160-E164.
45. Rogers J, Mahaney MC, Beamer W, Donahue LR, Rosen CJ Beyond one gene-one disease: alternative strategies for deciphering genetic determinants of osteoporosis. Calcif Tissue Int. 60:1997;225-228.
46. Sainz J, Van Tornout JM, Loro ML, Sayre J, Roe TF, Gilsanz V Vitamin D-receptor gene polymorphisms and bone density in prepubertal American girls of Mexican descent. New Engl J Med. 337:1997;77-82.
47. Salamone LM, Glynn N, Black DMet al. Determinants of premenopausal bone mineral density: the interplay of genetic and lifestyle factors. J Bone Miner Res. 11:1996;1557-1565.
48. Tokita A, Matsumoto H, Morrison NAet al. Vitamin D receptor alleles, bone mineral density and turnover in premenopausal Japanese women. J Bone Miner Res. 11:1996;1003-1009.
49. Uitterlinden AG, Pols HAP, Burger Het al. A large-scale population-based study of the association of vitamin D receptor gene polymorphisms with bone mineral density. J Bone Miner Res. 11:1996;1241-1248.
50. Viitanen AM, Kärkkälnen M, Laitinen Ket al. Common polymorphism of the vitamin D receptor gene is associated with variation of peak bone mass in young Finns. Calcif Tissue Int. 59:1996;231-234.
51. Wishart JM, Horowitz M, Need AGet al. Relations between calcium intake, calcitriol, polymorphisms of the vitamin D receptor gene, and calcium absorption in premenopausal women. Am J Clin Nutr. 65:1997;798-802.
52. Zmuda JM, Cauley JA, Danielson ME, Wolf RL, Ferrell RE Vitamin D receptor gene polymorphisms, bone turnover, and rates of bone loss in older African-American women. J Bone Miner Res. 12:1997;1446-1452.