High dose rate intraoperative radiation therapy (HDR-IORT) as part of the management strategy for locally advanced primary and recurrent rectal cancer

International Journal of Radiation Oncology Biology Physics

Volumn 42, Issue 2, 1998, Pages 325-330

  Harrison, Louis B ^a,b   Minsky, Bruce D ^a   Enker, Warren E ^a   Mychalczak, Borys ^a   Guillem, Jose ^a   Paty, Philip B ^a   Anderson, Lowell ^a   White, Carol ^a   Cohen, Alfred M ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b BETH ISRAEL MEDICAL CENTER   (United States)

Author keywords

High dose rate; Intraoperative radiation therapy; Rectal cancer

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; BEAM THERAPY; BRACHYTHERAPY; CANCER RECURRENCE; FEMALE; HUMAN; INTRAOPERATIVE PERIOD; MAJOR CLINICAL STUDY; MALE; METASTASIS; PRIORITY JOURNAL; RADIATION DOSE; RECTUM CANCER; SQUAMOUS CELL CARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTIDOTES; ANTIMETABOLITES, ANTINEOPLASTIC; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; FLUOROURACIL; HUMANS; INTRAOPERATIVE PERIOD; LEUCOVORIN; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; RADIOTHERAPY DOSAGE; RECTAL NEOPLASMS;

EID: 0032170659     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(98)00211-9     Document Type: Article

References (14)

1. Tepper J.E., Cohen A.M., Wood W.C., Hedberg S.E., Orlow E. Intraoperative electron beam radiotherapy in the treatment of unresectable rectal cancer. Arch Surg. 121:1986;421-423.
2. Tepper J.E., Wood W.C., Cohen A.M. Treatment of locally advanced rectal cancer with external beam radiation, surgical resection, and intraoperative radiation therapy. Int J Radiat Oncol Biol Phys. 16:1989;1437-1444.
3. Willett C., Shellito P.C., Tepper J.E., et al. Intraoperative electron beam radiation therapy for primary advanced rectal and rectosigmoid carcinoma. J Clin Oncol. 9:1991;843-849.
4. Wanebo H.J., Gaker D.L., Whitehill R., Morgan R.F., Constable W.C. Pelvic recurrence of rectal cancer. Ann Surg. 205:1986;482-495.
5. Wanebo H.J., Marcove R.C. Abdominal sacral resection of locally recurrent rectal cancer. Ann Surg. 194:1981;458-471.
6. Gunderson L.L., Cohen A.C., Dosoretz D.D., et al. Residual, unresectable, or recurrent colorectal cancer. External beam irradiation and intraoperative electron beam boost +/- resection. Int J Radiat Oncol Biol Phys. 9:1983;1597-1606.
7. Gunderson L.L., Dozois R.R. Intraoperative irradiation for locally advanced colorectal carcinomas. Perspect Col Rectal Surg. 5:1992;1-24.
8. Harrison L.B., Enker W.E., Anderson L. High dose rate intraoperative radiation therapy for colorectal cancer - Part 1. Oncology. 9:1995;679-683.
9. Harrison L.B., Enker W.E., Anderson L. High dose rate intraoperative radiation therapy for colorectal cancer - Part 2. Oncology. 9:1995;737-741.
10. Grann A., Minsky B., Cohen A., Saltz L., Guillem J., Paty P., Kelsen D., Kemeny N., Ilson D., Bass-Loeb J. Preliminary results of preoperative 5-Fluorouracil low dose Leucovorin, and concurrent radiation therapy for clinically resectable T3 rectal cancer. Dis Colon Rectum. 40:1997;515-522.
11. Kaplan E.L., Meier R. Non parametric estimations from incomplete observations. J Am Stat Assoc. 52:1958;457-480.
12. Gunderson L.L., Nelson H., Martenson J.A., Cha S., Haddock M., Devine R., Fieck J.M., Wolff B., Dozois R., O'Connell M.J. Intraoperative electron and external beam irradiation with or without 5-Fluorouracil and maximum surgical resection for previously unirradiated, locally recurrent colorectal cancer. Dis Colon Rectum. 39:1996;1379-1395.
13. Gunderson L.L., Nelson H., Martenson J.A., Cha S., Haddock M., Devine R., Fieck J.M., Wolff B., Dozois R., O'Connell M.J. Locally advanced primary colorectal cancer Intraoperative electron and external beam irradiation +/- 5-FU . Int. J. Rad. Onc. Biol. Phys. 37:1997;601-614.
14. Huber F.T., Stepan R., Zimmerman F., Fink V., Molls M., Siewert J.R. Locally advanced rectal cancer Resection and intraoperative radiotherapy using the flab method combined with preoperative or postoperative radiochemotherapy . Dis Colon Rectum. 39:1996;774-779.