Heterogeneity of the blood group A(x) allele: Genetic recombination of common alleles can result in the A(x) phenotype

Transfusion Medicine

Volumn 8, Issue 3, 1998, Pages 231-238

  Olsson, M L ^a   Chester, M A ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

ABO; Allele; Blood group; Genotyping; Recombination

Indexed keywords

ALLELE; BLOOD GROUP ANTIGEN; CLONED GENE; EXON; GENE SEQUENCING; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; INHERITANCE; INTRON; MUTATION; PHENOTYPE; SOUTHERN BLOTTING;

ABO BLOOD-GROUP SYSTEM; ALLELES; BLOOD GROUPING AND CROSSMATCHING; BLOTTING, SOUTHERN; FEMALE; GENETIC HETEROGENEITY; GENOTYPE; HUMANS; INTRONS; MALE; PEDIGREE; PHENOTYPE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECOMBINATION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 0032170084     PISSN: 09587578     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3148.1998.00161.x     Document Type: Article

References (12)

1. 4 occurring in the offspring of group O parents. Vox Sanguinis, 5, 145-147.
2. Bennett, E.P., Steffensen, R., Clausen, H., Weghuis, D.O. & van Kessel, A.G. (1995) Genomic cloning of the human histo-blood group ABO locus. Biochemical and Biophysical Research Communications, 206, 318-325.
3. Borg, A., Zhang, Q.X., Olsson, H. & Wenngren, E. (1992) Chromosome 1 alterations in breast cancer: allelic loss on 1p and 1q is related to lymphogenic metastases and poor prognosis. Genes Chromosomes Cancer, 5, 311-320.
4. 2B. Vox Sanguinis, 2, 8-15.
5. Cucca, F., Muntoni, F., Lampis, R., Frau, F., Cao, A., de Virgilis, S. & Congia, M. (1993) A novel HLA-DQB1 allele: evidence for gene conversion event promoted by chi-like sequence at DQB1 locus. Tissue Antigens, 41, 263-266.
6. Daniels, G.L. (1995) Human Blood Groups. Blackwell Scientific, Oxford.
7. 2B parent. Vox Sanguinis, 29, 390-393.
8. Ferguson-Smith, M.A., Aitken, D.A., Turleau, C. & de Grouchy, J. (1976) Localisation of the human ABO: Np-1: AK-1 linkage group by regional assignment of AK-1-9q34. Human Genetics, 34, 35-43.
9. 4 occurring in the offspring of group O parents. Vox Sanguinis, 4, 69-75.
10. Miller, S.A., Dykes, D.D. & Polesky, H.F. (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acid Research, 16, 1215-1218.
11. Mollicone, R., Reguigne, I., Kelly, R.J., Fletcher, A., Watt, J., Chatfield, S., Aziz, A., Cameron, H.S., Weston, B.W., Lowe, J.B. & Oriol, R. (1994) Molecular basis for Lewis α (1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees. Journal of Biological Chemistry, 269, 20987-20994.
12. Zago, M.A., Tavella, M.H., Simöes, B.P., Franco, R.F., Guerreiro, J.F. & Santos, S.B. (1996) Racial heterogeneity of DNA polymorphism linked to the A and the O alleles of the ABO blood group gene. Annals of Human Genetics, 60, 67-72.