Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of α-lytic protease

Biochemistry

Volumn 37, Issue 35, 1998, Pages 12058-12067

  Peters, Reuben J ^a   Shiau, Andrew K ^a   Sohl, Julie L ^b   Anderson, D Eric ^a   Tang, Gale ^b   Silen, Joy L ^c   Agard, David A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c AFFYMAX RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DENATURATION; ENZYME INHIBITION; ENZYME RELEASE; GENE DELETION; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; SOIL MICROFLORA;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; GRAM-NEGATIVE BACTERIA; MODELS, MOLECULAR; MUTAGENESIS, INSERTIONAL; PEPTIDE FRAGMENTS; PROTEIN FOLDING; SEQUENCE DELETION; SERINE ENDOPEPTIDASES;

BACTERIA (MICROORGANISMS); FELIS CATUS; GENETTA;

EID: 0032169518     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980883v     Document Type: Article

References (31)

1. Fujinaga, M., Delbaere, L. T. J., Brayer, G. D., and James, M. N. G. (1985) J. Mol. Biol. 184, 479.
2. Schechter, I., and Berger, A. (1968) Biochem. Biophys. Res. Commun. 27.
3. Silen, J. L., and Agard, D. A. (1989) Nature 341, 462-464.
4. Baker, D., Sohl, J. L., and Agard, D. A. (1992) Nature 356, 263-265.
5. Sohl, J. L., Jaswal, S. S., and Agard, D. A. (1998) Nature (in press).
6. Baker, D., Silen, J. L., and Agard, D. A. (1992) Proteins 12, 339-344.
7. Sohl, J. L., Shiau, A. K., Rader, S. D., Wilk, B., and Agard, D. A. (1997) Biochemistry 36, 3894-3902.
8. Whitaker, D. R. (1970) Methods Enzymol. 19, 599-613.
9. Silen, J. L., Frank, D., Fujishige, A., Bone, R., and Agard, D. A. (1989) J. Bacteriol. 171, 1320-1325.
10. Studier, F. W., Rosenberg, A. H., Dunn, J. J., and Dubendorff, J. W. (1990) Methods Enzymol. 185, 60-89.
11. Mace, J. E., Wilk, B. J., and Agard, D. A. (1995) J. Mol. Biol. 251, 116-134.
12. Mace, J. E., and Agard, D. A. (1995) J. Mol. Biol. 254, 720-736.
13. Zimmerle, C. T., and Frieden, C. (1989) Biochem. J. 258, 381-387.
14. Brayer, G. D., Delbaere, L. T. J., and James, M. N. G. (1979) J. Mol. Biol. 131, 743-775.
15. Brunger, A. T., Kuriyan, J., and Karplus, M. (1987) Science 35, 458-460.
16. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950.
17. Kettner, C. A., Bone, R., Agard, D. A., and Bachovchin, W. W. (1988) Biochemistry 27, 7682-7688.
18. Bone, R., Shenvi, A. B., Kettner, C. A., and Agard, D. A. (1987) Biochemistry 26, 7609-7614.
19. Bone, R., Frank, D., Kettner, C. A., and Agard, D. A. (1989) Biochemistry 28, 7600-7609.
20. Reidhaar-Olson, J. F., and Agard, D. A. (manuscript in preparation).
21. Winther, J. R., and Sorensen, P. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 9330-9334.
22. Segundo, B. S., Martinez, M. C., Vilanova, M., Cuchillo, C. M., and Aviles, F. X. (1982) Biochim. Biophys. Acta 707, 74-80.
23. Strausberg, S., Alexander, P., Wang, L., Schwarz, F., and Bryan, P. (1993) Biochemistry 32, 8112-8119.
24. Fusek, M., Mares, M., Vagner, J., Voburka, Z., and Baudys, M. (1991) FEBS Lett. 287, 160-162.
25. Fox, T., de Miguel, E., Mort, J. S., and Storer, A. C. (1992) Biochemistry 31, 12571-12576.
26. Ohta, Y., et al. (1991) Mol. Microbiol. 5, 1507-1510.
27. Gallagher, T., Gilliland, G., Wang, L., and Bryan, P. (1995) Structure 3, 907-914.
28. Bryan, P., et al. (1992) Biochemistry 31, 4937-4945.
29. Li, Y., Hu, Z., Jordan, F., and Inouye, M. (1995) J. Biol. Chem. 270, 25127-25132.
30. Wang, L., et al. (1995) Biochemistry 34, 15415-15420.
31. Fujishige, A., Smith, K. R., Silen, J. L., and Agard, D. A. (1992) J. Cell Biol. 118, 33-42.