Resistance of aryl-substituted phenylalanines to decarboxylation in the rat

General Pharmacology

Volumn 31, Issue 3, 1998, Pages 437-440

  Goodwin, Brian L ^a   Ruthven, Colin R J ^a   Sandler, Merton ^a,b  

^a QUEEN CHARLOTTE S AND CHELSEA HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

phenylethylamines; Aryl substituted phenylalanines; Phenylacetic acids; Phenyllactic acids; Phenylpyruvic acids; Rat

Indexed keywords

PHENETHYLAMINE DERIVATIVE; PHENYLACETIC ACID DERIVATIVE; PHENYLALANINE DERIVATIVE; PHENYLPYRUVIC ACID;

ARTICLE; DECARBOXYLATION; DRUG EXCRETION; DRUG METABOLISM; DRUG STRUCTURE; FEMALE; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; DECARBOXYLATION; FEMALE; OXIDATION-REDUCTION; PHENETHYLAMINES; PHENYLALANINE; PHENYLPYRUVIC ACIDS; RATS; RATS, WISTAR; TYROSINE;

EID: 0032168484     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(98)00017-2     Document Type: Article

References (24)

1. Armstrong M.D., Shaw K.N.F., Robinson K.S. Studies on phenylketonuria II. the excretion of -hydroxyphenylacetic acid in phenylketonuria J. Biol Chem. 213:1955;797-804.
2. Blaschko H. The decarboxylation of -hydroxyphenylalanine. Biochem. J. 44:1949;268-274.
3. Blaschko H. Substrate specificity of amino-acid decarboxylases. Biochim. Biophys. Acta. 4:1950;130-137.
4. Blau K. (1979) Phenylalanine hydroxylase deficiency: biochemical, physiological, and clinical aspects of phenylketonuria and related phenylalaninemias. In Aromatic Amino Acid Hydroxylase and Mental Disease (Edited by Youdim M. B. H.), p. 77-139. Wiley, Chichester, UK.
5. Blau K., Goodwin B., Woods H.F., Youdim M.B.H. Phenylethylamine formation in perfused rat liver. Br. J. Pharmac. 58:1976;474P.
6. Bloxham H.R., Day M.G., Gibbs N.K., Woolf L.I. An inborn defect in the metabolism of tyrosine in infants on a normal diet. Biochem J. 77:1960;320-326.
7. Brossi A., Schenker F., Schmidt R., Banziger R., Leimgruber W. Synthesen in der Isochinolinreihe. Helv. Chim. Acta. 49:1966;403-411.
8. Cammarata P.S., Cohen P.P. The scope of the transamination reaction in animal tissues. J. Biol. Chem. 187:1950;439-452.
9. Fölling A. Über Ausscheidung von Phenylbrenztraubensäure in den Harn als Stoffwechselanomalie in Verbindung mit Imbezillität. Hoppe-Seyler's Z. Physiol. Chem. 227:1934;169-176.
10. Gale E.F. The production of amines by bacteria 2. the production of tyramine by Streptococcus faecalis Biochem. J. 44:1940;846-852.
11. Goodwin B.L. Tyrosine Catabolism. 1972;Clarendon Press, Oxford.
12. Goodwin B. L. (1979) Phenylalanine hydroxylase. In Aromatic Amino Acid Hydroxylase and Mental Disease (Edited by Youdim M. B. H.), pp. 5-76. Wiley, Chichester, UK.
13. Goodwin B.L., Sandler M. Improved resolution using capillary columns. Clin. Chim. Acta. 59:1975;253-254.
14. Goodwin B.L., Johnson R.D., Leask B.G.S., Ruthven C.R.J., Sandler M. threo-3,4,-Dihydroxyphenylserine, a poor source of noradrenaline in the rat. Experientia. 28:1972;1298-1299.
15. Goodwin B.L., Ruthven C.R.J., Sandler M. Gas chromatographic estimation of urinary homovanillic and 4-hydroxy-3-methoxy-mandelic acids using capillary columns. Clin. Chim. Acta. 55:1974;111-112.
16. Goodwin B.L., Ruthven C.R.J., Sandler M. Gas chromatographic assay of phenylacetic acid in biological fluids. Clin. Chim. Acta. 62:1975;443-446.
17. Goodwin B.L., Ruthven C.R.J., King G.S., Sandler M., Leask B.G.S. Metabolism of 3,4-dihydroxyphenylalanine, its metabolites and analogues in vivo in the rat. urinary excretion pattern Xenobiotica. 8:1978;629-651.
18. Gopalakrishna Y., Narayanan T.K., Rao G.R. Synthesis of β-phenethyl alcohol in Candida guilliermondii. Biochem. Biophys. Res. Commun. 69:1976;417-422.
19. Schwenk E., Bloch E. New modification of Willgerodt's reaction. J. Am. Chem. Soc. 64:1942;3051-3052.
20. Sealock R.R., Speeter M.E., Schweet R.S. The synthesis, resolution, and proof of configuration of isomers of m-tyrosine. J. Am. Chem. Soc. 73:1951;5386-5388.
21. Shaw K.N.F., Armstrong M.D., McMillan A. Preparation of m-hydroxyphenyl-L- and D-lactic acids and other compounds related to m-tyrosine. J. Org. Chem. 21:1956;1149-1151.
22. Vogel A. I. (1961) A Textbook of Practical Organic Chemistry, 3rd edn, pp. 923-925. Longmans, London.
23. Waser E. Decarboxylation of tyrosine and leucine. Helv. Chim. Acta. 8:1925;758-773.
24. Woolf L. I. (1951) Excretion of conjugated phenylacetic acid in phenylketon-uria. Biochem. J. 49, ix.