Drug withdrawal convulsions and susceptibility to convulsants after short-term selective breeding for acute ethanol withdrawal

Behavioural Brain Research

Volumn 95, Issue 1, 1998, Pages 113-122

  Metten, Pamela ^a   Belknap, John K ^a   Crabbe, John C ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Correlated responses; Dependence; Ethanol; Pharmacogenetics; Seizures; Selectively bred mice; Withdrawal; Zolpidem

Indexed keywords

ANESTHETIC AGENT; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; IMIDAZOPYRIDINE DERIVATIVE; INHALATION ANESTHETIC AGENT; NITROUS OXIDE;

ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREEDING; CONTROLLED STUDY; CONVULSION; DRUG WITHDRAWAL; FEMALE; MALE; NONHUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; WITHDRAWAL SYNDROME;

ANIMALS; AREA UNDER CURVE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONVULSANTS; ETHANOL; FEMALE; INFUSIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; SEIZURES; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0032168421     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(97)00216-7     Document Type: Article

References (39)

1. Belknap JK, Crabbe JC, Laursen SE. Ethanol and diazepam withdrawal convulsions are extensively codetermined in WSP and WSR mice. Life Sci. 44(26):1989;2075-2080.
2. Belknap JK, Danielson PW, Lame M, Crabbe JC. Ethanol and barbiturate withdrawal convulsions are extensively codetermined in mice. Alcohol. 5(2):1988;167-171.
3. Belknap JK, Laursen SE, Crabbe JC. Ethanol and nitrous oxide produce withdrawal-induced convulsions by similar mechanisms in mice. Life Sci. 41(17):1987;2033-2040.
4. Crabbe JC, Kosobud A, Young ER, Tam BR, McSwigan JD. Bidirectional selection for susceptibility to ethanol withdrawal seizures in Mus musculus. Behav Genet. 15:1985;521-536.
5. Crabbe JC Jr, Young ER, Kosobud A. Genetic correlations with ethanol withdrawal severity. Pharmacol Biochem Behav. 18(Suppl. 1):1983;541-547.
6. Goldstein DB. Inherited differences in intensity of alcohol withdrawal reactions in mice. Nature. 245(September 21):1973;154-156.
7. Belknap JK, Metten P, Helms ML, O'Toole LA, Angeli-Gade S, Crabbe JC, Phillips TJ. Quantitative trait loci (QTL) applications to substances of abuse: physical dependence studies with nitrous oxide and ethanol in BXD mice. Behav Genet. 23(2):1993;213-222.
8. Crabbe JC, Merrill C, Belknap JK. Acute dependence on depressant drugs is determined by common genes in mice. J Pharmacol Exp Ther. 257(2):1991;663-667.
9. Metten P, Crabbe JC. Common genetic determinants of severity of acute withdrawal from ethanol, pentobarbital and diazepam in inbred mice. Behav Pharmacol. 5:1994;533-547.
10. Roberts AJ, Crabbe JC, Keith LD. Corticosterone increases severity of acute withdrawal from ethanol, pentobarbital and diazepam in mice. Psychopharmacology. 115(1-2):1994;278-284.
11. Metten P, Crabbe JC Dependence and withdrawal. Deitrich RA, Erwin VG Pharmacological Effects of Ethanol on the Nervous System. 1996;269-290 CRC Press, Boca Raton, FL.
12. Buck KJ, Metten P, Belknap JK, Crabbe JC Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice. J Neurosci. 17(10):1997;3946-3955.
13. Belknap JK, Richards SP, O'Toole LA, Helms ML, Phillips TJ Short term selective breeding as a tool for QTL mapping: Ethanol preference drinking in mice. Behav Genet. 27(1):1997;55-66.
14. Crabbe JC, Phillips TJ, Kosobud A, Belknap JK. Estimation of genetic correlation: interpretation of experiments using selectively bred and inbred animals. Alcohol Clin Exp Res. 14(2):1990;141-151.
15. Buck KJ. Molecular genetic analysis of the role of GABAergic systems in the behavioral and cellular actions of alcohol. Behav Genet. 26(3):1996;313-323.
16. Tabakoff B, Hoffman PL Ethanol and glutamate receptors. Deitrich RA, Erwin VG Pharmacological Effects of Ethanol on the Nervous System. 1996;73-93 CRC Press, Boca Raton, FL.
17. Kosobud AE, Crabbe JC. Genetic correlations among inbred strain sensitivities to convulsions induced by 9 convulsant drugs. Brain Res. 526(1):1990;8-16.
18. Falconer DS, Mackay TFC Introduction to Quantitative Genetics. 4th ed:1996;Longman, London.
19. Eidman DS, Benedito MAC, Leite JR. Daily changes in pentylenetetrazol-induced convulsions and open-field behavior in rats. Physiol Behav. 47:1990;853-856.
20. Roberts AJ, Keith LD. Sensitivity of the circadian rhythm of kainic acid-induced convulsion susceptibility to manipulations of corticosterone levels and mineralocorticoid receptor binding. Neuropharmacology. 33:1994;1087-1093.
21. Schoch P, Moreau JL, Martin JR, Haefely WE. Aspects of benzodiazepine receptor structure and function with relevance to drug tolerance and dependence. Biochem Soc Symp. 59:1993;121-134.
22. Perrault G, Morel E, Sanger DJ, Zivkovic B. Lack of tolerance and physical dependence upon repeated treatment with the novel hypnotic zolpidem. J Pharmacol Exp Ther. 263(1):1992;298-303.
23. VonVoigtlander PF, Lewis RA. A rapid screening method for the assessment of benzodiazepine receptor-related physical dependence in mice. Evaluation of benzodiazepine-related agonists and partial agonists. J Pharmacol Methods. 26(1):1991;1-5.
24. Goldstein DB. Rates of onset and decay of alcohol physical dependence in mice. J Pharmacol Exp Ther. 190:1974;377-383.
25. Im HK, Im WB, Hamilton BJ, Carter DB, VonVoigtlander PF. Potentiation of γ-aminobutyric acid-induced chloride currents by various benzodiazepine site agonists with the α1 γ2, β2, γ2 and α1, β2, γ2 subtypes of cloned γ-aminobutyric acid type A receptors. Mol Pharmacol. 44(4):1993;866-870.
26. McKernan RM, Whiting PJ. Which GABAA-receptor subtypes really occur in the brain? Trends Neurosci. 19:1996;139-143.
27. - ion channels modulated by multiple drug-binding sites. Trends Pharmacol Sci. 13:1992;446-450.
28. Mihic SJ, Harris RA Alcohol actions at the GABAA receptor/chloride channel complex. Deitrich RA, Erwin VG Pharmacological Effects of Ethanol on the Nervous System. 1996;51-72 CRC Press, Boca Raton, FL.
29. Brennan CH, Crabbe J, Littleton JM. Genetic regulation of dihydropyridine-sensitive calcium channels in brain may determine susceptibility to physical dependence on alcohol. Neuropharmacology. 29(5):1990;429-432.
30. Little HJ. The role of neuronal calcium channels in dependence on ethanol and other sedatives/hypnotics. Pharmacol Ther. 50:1991;347-365.
31. Little HJ, Dolin SJ, Halsey MJ. Calcium channel antagonists decrease the ethanol withdrawal syndrome. Life Sci. 39:1986;2059-2065.
32. McSwigan JD, Crabbe JC, Young ER. Specific ethanol withdrawal seizures in genetically selected mice. Life Sci. 35:1984;2119-2126.
33. Kosobud A, Crabbe JC Genetic influences on the development of alcohol dependence and withdrawal. Begleiter H, Kissin B The Genetics of Alcoholism. 1995;221-256 Oxford University Press, London.
34. Kosobud AE, Cross SJ, Crabbe JC. Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice. Brain Res. 592(1-2):1992;122-128.
35. Kosobud AE, Crabbe JC. Sensitivity to N-methyl-D-aspartic acid-induced convulsions is genetically associated with resistance to ethanol withdrawal seizures. Brain Res. 610:1993;176-179.
36. Goldstein DB. Relationship of alcohol dose to intensity of withdrawal signs in mice. J Pharmacol Exp Ther. 180:1972;203-215.
37. Ferraro TN, Golden GT, Smith GG, Schork NJ, Jean PS, Ballas C, Cho H, Berrettini WH Mapping murine loci for seizure response to kainic acid. Mamm Genome. 8:1997;200-208.
38. Kamatchi GL, Kofuji P, Wang JB, Fernando JC, Liu Z, Mathura JRJ, Burt DR. GABAA receptor β1, β2 and β3 subunits: comparisons in DBA/2J and C57BL/6J mice. Biochim Biophys Acta. 1261(1):1995;134-142.
39. A receptor: comparison in seizure prone and resistant mice and during development. J Mol Neurosci. 3(4):1992;177-184.