Differential roles for disulfide bonds in the structural integrity and biological activity of κ-bungarotoxin, a neuronal nicotinic acetylcholine receptor antagonist

Biochemistry

Volumn 37, Issue 35, 1998, Pages 12166-12171

  Grant, Gregory A ^a   Luetje, Charles W ^b   Summers, Roger ^a   Xu, Xiao Lan ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUNGAROTOXIN; NICOTINIC RECEPTOR;

AMINO ACID METABOLISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DISULFIDE BOND; DRUG RECEPTOR BINDING; GENE DELETION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS;

ALANINE; ANIMALS; BUNGAROTOXINS; CIRCULAR DICHROISM; CYSTEINE; DISULFIDES; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NEURONS; NICOTINIC ANTAGONISTS; OOCYTES; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; XENOPUS LAEVIS;

BUNGARUS FASCIATUS; BUNGARUS MULTICINCTUS; INVERTEBRATA; SERPENTES;

EID: 0032168390     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981227y     Document Type: Article

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