Structure of 3,4-dichloroisocoumarin-inhibited factor D

Acta Crystallographica Section D: Biological Crystallography

Volumn 54, Issue 5, 1998, Pages 711-717

  Cole, L Brent ^a,b   Kilpatrick, J Michael ^a,b   Chu, Naiming ^a,b   Babu, Y Sudhakar ^a,b  

^a BIOCRYST PHARMACEUTICALS INC   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(1 (5 CHLORO 4 OXO 4H 3,1 BENZOXAZIN 2 YL) 2 METHYLPROPYL)CARBAMIC ACID 1,1 DIMETHYLETHYL ESTER; (1-(5-CHLORO-4-OXO-4H-3,1-BENZOXAZIN-2-YL)-2-METHYLPROPYL)CARBAMIC ACID 1,1-DIMETHYLETHYL ESTER; 3,4 DICHLOROISOCOUMARIN; 3,4-DICHLOROISOCOUMARIN; CARBAMIC ACID DERIVATIVE; COMPLEMENT FACTOR D; COMPLEMENT FACTOR D, HUMAN; COUMARIN DERIVATIVE; OXAZINE DERIVATIVE; PANCREATIC ELASTASE; SERINE PROTEINASE INHIBITOR;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; COMPLEMENT ALTERNATIVE PATHWAY; CRYSTALLIZATION; DRUG ANTAGONISM; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SWINE; X RAY CRYSTALLOGRAPHY;

ANIMALS; CARBAMATES; COMPLEMENT FACTOR D; COMPLEMENT PATHWAY, ALTERNATIVE; COUMARINS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OXAZINES; PANCREATIC ELASTASE; PROTEIN CONFORMATION; SERINE PROTEINASE INHIBITORS; SWINE;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0032168036     PISSN: 09074449     EISSN: None     Source Type: Journal    
DOI: 10.1107/S0907444997010457     Document Type: Article

References (28)

1. Barnum, S. R., Niemann, M. A., Kearney, J. F. & Volanakis, J. E. (1984). J. Immunol. Methods, 67, 303-309.
2. Brünger, A. T. (1990). Acta Cryst. A46, 46-47
3. Brünger, A. T. (1992a). X-PLOR: A System for X-ray Crystallography and NMR. Version 3.1. New Haven and London: Yale University Press.
4. Brünger, A. T. (1992b). Nature (London), 355, 472-475.
5. Bugg, C. E., Carson, W. M. & Montgomery, J. A. (1993). Sci. Am. 296(6), 92-98.
6. Chow, M. M., Meyer, E. F., Bode, W., Kam, C.-M., Radhakrishnan, R., Vijayalakshmi, J. & Powers, J. C. (1990). J. Am. Chem. Soc. 112(21), 7783-7789.
7. Cole, L B., Chu, N., Kilpatrick, J. M., Volanakis, J. E., Narayana, S. V. L. & Babu, Y. S. (1997). Acta Cryst. D53, 143-150.
8. Cryer, H. G., Richardson, J. D., Longmire-Cook, S. & Brown, C. M. (1989). Arch. Surg. 124, 1378-1385.
9. Fearon, D. T., Austen, K. F. & Ruddy, S. (1974). J. Exp. Med. 139, 355-366.
10. Hansson, G. K., Jonasson, L., Seifert, P. S. & Stemme, S. (1989). Atherosclerosis, 9, 567-578.
11. Howard, A. J. Gilliland, G. L., Finzel, B. C., Poulos, T. L., Ohelendorf, D. H. & Salemme, F. R. (1987). J. Appl. Cryst. 20, 383-387.
12. Jones, T. A. (1978). J. Appl. Cryst. 11, 268-272.
13. Kam, C.-M., McRae, B. J., Harper, J. W., Niemann, M. A., Volanakis, J. E. & Powers, J. C. (1987). J. Biol. Chem. 262, 3444-3451.
14. Kam, C.-M., Oglesby, T. J., Pangburn, M. K., Volanakis, J. E. & Powers, J. C. (1992). J. Immunol. 149, 163-168.
15. Kerrigan, J. E., Oleksyszyn, J., Kam, C. M., Selzler, J. & Powers, J. C. (1995). J. Med. Chem. 38, 544-552.
16. Kleywegt, G. J. & Brünger, A. T. (1996). Structure, 4(8), 897-904.
17. Laskowski, R. A., MacArthur, M. W., Moss, D. S. & Thornton, J. M. (1993). J. Appl. Cryst. 26, 283-291.
18. Lesavre, P. H., Hugli, T. E., Esser, A. F. & Muller-Eberhard, H. J. (1979). J. Immunol. 123, 529-534.
19. Lesavre, P. H. & Muller-Eberhard, H. J. (1978). J. Exp. Med. 148, 1498-1509.
20. Narayana, S. V. L., Carson, M., El-Kabbani, O., Kilpatrick, J. M., Moore, D., Chen, X., Bugg, C. E., Volanakis, J. E. & DeLucas, L. J. (1994). J. Mol. Biol. 235, 695-708.
21. Nicholls, A., Sharp, K. A. & Honig, B. (1991). Proteins, 11(4), 282-296.
22. Niemann, M. A., Bhown, A. S., Bennett, J. C. & Volanakis, J. E. (1984). Biochemistry, 23, 2482-2486.
23. Powers, J. C. & Kam, C.-M. (1994). Methods Enzymol. 244, 442-457.
24. Radhakrishnan, P., Presta, L. G., Meyer, E. F. Jr & Wildonger, R. (1987). J. Mol. Biol. 198, 417-124.
25. Salvesen, N. G. & Nagase, H. (1989). Proteolytic Enzymes, A Practical Approach, edited by R. J. Beyon & J. A. Bond, pp. 83-104. New York: IRL Press.
26. Volanakis, J. E., Barnum, S. R. & Kilpatrick, J. M. (1993). Methods Enzymol. 223, 82-97.
27. Volanakis, J. E. & Macon, K. J. (1987). Anal. Biochem. 163, 242-246.
28. Yasuda, M., Takeuchi, K., Hiruma, M., Iida, H., Tahara, A., Itagane, H., Toda, I., Akioka, K., Teragaki, M., Oku, H., Kanayama, Y., Takeda, T., Kolb, W. P. & Tamerius, J. D. (1990). Circulation, 81(1), 156-163.