Blood flow and leukocyte adhesiveness are reduced in the microcirculation of a peritoneal disseminated colon carcinoma

Annals of Biomedical Engineering

Volumn 26, Issue 5, 1998, Pages 803-811

  Suzuki, Toshishige ^a,b   Yanagi, Kennichi ^a   Ookawa, Keiko ^a   Hatakeyama, Katsuyoshi ^b   Ohshima, Norio ^a,c  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Angiogenesis; Real time confocal laser scanning microscope; Shear rate; Tumor microcirculation

Indexed keywords

ADHESION; ANIMAL; ARTICLE; BLOOD; BLOOD FLOW VELOCITY; BLOOD RHEOLOGY; COLON TUMOR; CONFOCAL MICROSCOPY; DISEASE MODEL; EXPERIMENTAL NEOPLASM; FISCHER 344 RAT; LEUKOCYTE; MALE; METASTASIS; MICROCIRCULATION; PATHOLOGY; PATHOPHYSIOLOGY; PERITONEUM TUMOR; PHYSIOLOGY; RAT;

ADHESIVENESS; ANIMALS; BLOOD FLOW VELOCITY; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; HEMORHEOLOGY; LEUKOCYTES; MALE; MICROCIRCULATION; MICROSCOPY, CONFOCAL; NEOPLASMS, EXPERIMENTAL; PERITONEAL NEOPLASMS; RATS; RATS, INBRED F344;

EID: 0032159131     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.67     Document Type: Article

References (23)

1. Adamson, R. H., J. F. Lentz, and F. E. Curry. Quantitative laser scanning confocal microscopy on single capillaries: Permeability measurement. Microcirculation (N.Y.) 1:251-265, 1994.
2. Brakenhoff, G., and K. Visscher. Confocal imaging with bilateral scanning and array detectors. J. Microsc. 165:139-146, 1992.
3. Folkman, J. Tumor angiogenesis. Advn. Cancer Res. 43:175-203, 1985.
4. Fukumura, D., H. A. Salehi, B. Witwer, R. F. Tuma, R. J. Melder, and R. K. Jain. Tumor necrosis factor a-induced leukocyte adhesion in normal and tumor vessel: effect of tumor type, transplantation site, and host strain. Cancer Res. 55:4824-4829, 1995.
5. Gallik, S., S. Usami, K.-M. Jan, and S. Chien. Shear stress-induced detachment of human polymorphonuclear leukocytes from endothelial cell monolayers. Biorheology 26:823-834, 1989.
6. Homma, S., M. Sato, Y. Sugishita, and N. Ohshima. Flow behavior of erythrocytes in living microvessels: analysis of the distribution of dynamic hematocrits measured in vivo. Int. J. Multiphase Flow 19:897-904, 1993.
7. Hori, K., Q. Zhang, S. Saito, S. Tanda, H. Li, and M. Suzuki. Microvascular mechanisms of change in tumor blood flow due to angiotensin II, epinephrine, and methoxamin: a functional morphometric study. Cancer Res. 53:5528-5534, 1993.
8. Inoue, Y., Y. Kashima, K. Aizawa, and K. Hatakeyama. A new rat colon cancer cell line metastasizes spontaneously: Biologic characteristics and chemotherapeutic response. Jpn. J. Cancer Res. 82:90-97, 1991.
9. Jain, R. K. Determinants of tumor blood flow: a review. Cancer Res. 48:2641-2658, 1988.
10. Leunig, M., and K. Messmer. Intravital microscopy in tumor biology: current status and future perspective (Review). Int. J. Oncol. 6:413-417, 1995.
11. Ley, K., and P. Gaehtgens. Endothelial. not hemodynamic, differences are responsible for preferential leukocyte rolling in rat mesenteric venules. Circ. Res. 69:1034-1041, 1991.
12. Lorenzl, S., U. Koedel, U. Dimagl, G. Ruchdeschel, and H. W. Prister. Imaging of leukocyte-endothelium interaction using in vivo confocal laser scanning microscopy during the earty phase of experimental pneumococcal meningitis. J. Infect. Dis. 168:927-933, 1993.
13. Melder, R. J., H. A. Salhei, and R. K. Jain. Interaction of activated natural killer cells with normal and tumor vessels in cranial windows in mice. Microvasc. Res. 50:35-44, 1995.
14. Merchant, F., S. Aggarwal, K. Diller, and A. Bovik. In-vivo analysis of angiogenesis and revascularization of transplanted pancreatic islets using confocal microscopy. J. Microsc. 176:262-275, 1994.
15. Ohkubo, C., D. Bigos, and R. K. Jain. Interleukin 2 induced leukocyte adhesion to the normal and tumor microvasculature endothelium in vivo and its inhibition by dextran sulfate: implications for vascular leak syndrome. Cancer Res. 51:1561-1563, 1991.
16. Suzuki, T., K. Yanagi, K. Ookawa, K. Hatakeyama, and N. Ohshima. Flow visualization of the microcirculation in solid tumor tissues: intravital microscopic observation of blood circulation by use of a confocal laser scanning microscope. Front. Med. Biol. Eng. 7:253-263, 1996.
17. Wu, N. Z., B. Klitzman, R. Dodge, and M. W. Dewhirst. Diminished leukocyte-endothelium interaction in tumor microvessels. Cancer Res. 52:4265-4268, 1992.
18. Wu, N. Z., B. A. Ross, C. Gulledge, B. Klitzman, R. Dodge, and M. W. Dewhirst. Differences in leukocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation. Br. J. Cancer 69:883-889, 1994.
19. Yamaguchi, K., K. Nishio, N. Sato, H. Tsumura, A. Ichihara, H. Kudo, T. Aoki, K. Naoki, K. Suzuki, A. Miyata, Y. Suzuki, and S. Morooka. Leukocyte kinetics in the pulmonary microcirculation: Observations using real-time confocal luminescence microscopy coupled with high-speed video analysis. Lab. Invest. 76:809-822, 1997.
20. Yanagi, K., and N. Ohshima. Intravital observation of microvasculature of an inoculated tumor under intravital near-infrared fluorescence microscope: a study using peritoneal disseminated tumor model. In: Progress in Microcirculation Research, edited by H. Niimi, M. Oda, T. Sawada, and R. Xiu. Oxford: Elsevier Science Ltd., 1994, pp. 437-440.
21. Yanagi, K., and N. Ohshima, Angiogenic vascular growth in the rat peritoneal disseminated tumor model. Microvasc. Res. 51:15-28, 1996.
22. Yuan, F., D. Fukumura, M. Leunig, V. P. Torchilin, and R. K. Jain. Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size. Cancer Res. 55:3752-3756, 1995.
23. Yuan, F., K. A. Salehi, U. S. Vasthare, R. F. Tuma, and R. K. Jain. Vascular permeability and microcirculation of gliomas and mammary carcinomas transplanted in rat and mouse cranial windows. Cancer Res. 54:4564-4568, 1994.