Hepatitis viruses and hepatocellular carcinoma

Research in Virology

Volumn 149, Issue 5, 1998, Pages 257-262

  Kew, M C ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

Chronic necroinflammatory hepatic disease; HBV; HCV; Hepatocellular carcinoma; Review

Indexed keywords

CANCER RISK; CONFERENCE PAPER; DISEASE ASSOCIATION; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C VIRUS; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0032158319     PISSN: 09232516     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2516(99)89003-7     Document Type: Conference Paper

References (57)

1. Arbuthnot, P., Kew, M.C. & Fitschen, W. (1991), c-fos and c-myc oncogene expression in human hepatocellular carcinomas. Anti-Cancer Res., 11, 921-924.
2. Beasley, R.P. & Hwang, L-Y. (1984), Epidemiology of hepatocellular carcinoma, in: "Viral Hepatitis and Liver Disease" (Vyas GN, Dienstag JL, Hoofnagle JH) (pp. 209-224). Grune & Stratton: Orlando.
3. Benvegnu, L. & Alberti, A. (1996), Risk factors and prevention of hepatocellular carcinoma in HCV infection. Dig. Dis. Sci., 12, 49S-55S.
4. Botha, J.F., Ritchie, M.J.J., Dusheiko, G.M., Mouton, H.W.K. & Kew, M.C. (1984), Hepatitis B virus carrier state in black children in Ovamboland: Role of perinatal and horizontal infection. Lancet, 2, 1210-1212.
5. Bruno, S., Silini, E., Croigani, A., Borzio, F., Leandro, G., Bono, F., Asti, M., Rossi, S., Larghi, H., Cerino, A., Podda, M. & Mondelli, M.U. (1997), Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: A prospective study. Hepatology, 25, 754-758.
6. Chang, M-H., Chen, C-J., Lai, M-S., Hsu, H-M., Wu, T-C., Kong, M-S., Liang, D-C., Shau, W-Y. & Chen, D-S. (1997), Universal hepatitis B vaccination in Taiwan and the incidence of heoatocellular carcinoma in children. N. Engl. J. Med., 336, 1855-1859.
7. Castells, L., Vargas, V., Gonzalez, A., Esteban, J., Esteban, R. & Guardia, J. (1995), Long interval between HCV infection and development of hepatocellular carcinoma. Liver, 15, 159-163.
8. Chisari, F.V., Klopchin, K., Moriyama, T., Pasquinelli, C., Dunsford, H.A., Sell, S., Brinster, R.L. & Palmiter, R.D. (1989), Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell, 5, 1145-1156.
9. De Mitri, M.S., Poussin, K., Baccarini, P., Pontisso, P., D'Errico, A., Simon, N., Grigione, W., Alberti, A., Beaugrand, M., Pisi, E., Brechot, C. & Paterlini, P. (1995), HCV-associated liver cancer without cirrhosis. Lancet, 345, 413-415.
10. DiBisceglie, A.M., Simpson, L.H., Lotze, M.T. & Hoofnagle, J.H. (1994), Development of hepatocellular carcinoma among patients with chronic liver disease due to hepatitis C viral infection. J. Clin. Gastroenterol., 19, 222-226.
11. Fattovich, G., Giustina, G., Degos, F., Diodati, G., Tremolada, F., Nevens, F., Almasio, P., Solinas, A., Brouwer, J.T., Thomas, H., Realdi, G., Coorocher, R. & Schalm, S.W. (1997), Effectiveness of α-interferon on incidence of HCC and decompensation in cirrhosis type C. J. Hepatol., 27, 201-205.
12. Feitelsohn, M.A., Zhu, M., Duan, I.L.X. & London, W.T. (1993), Hepatitis B X antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma. Carcinogen, 8, 1109-1117.
13. Freeman, B.A. & Crapo, J.D. (1982), Biology of disease: Free radicles and tissue injury. Lab. Invest., 47, 412-426.
14. Haydon, G.H., Jarvis, L.M., Simmonds, P., Harrison, D.J., Garden, O.J. & Hayes, P.C. (1997), Association between hepatitis C infection and hepatocellular carcinoma in a Scottish population. Gut, 40, 128-132.
15. Henkler, F. & Koshy, R. (1996), Hepatitis B virus transcriptional activators: mechanisms and possible role in oncogenesis. J. Vir. Hepatit., 3, 109-121.
16. Hsu, T.Y., Fourel, J., Etiemble, J., Tiollais, P. & Buendia, M.A. (1990), Integration of hepatitis B virus DNA near c-myc in woodchuck hepatocellular carcinoma. Gastroenterol. Jpn., 25, (Suppl 2), 43-48.
17. Hwang, S-J., Tong, M.J., Lai, P.P.C., Ko, E.S., Co, R.L., Chien, C. & Kuo, G. (1996), Evaluation of hepatitis B and C viral markers: Clinical significance in Asian and Caucasian patients with hepatocellular carcinoma in the United States of America. J. Gastroenterol. Hepatol., 11, 949-954.
18. International Agency for Research on Cancer Monographs on the Evaluation of Carcinogenic Risks to Humans. Vol 59. Hepatitis Viruses. Lyon, IARC. 1994.
19. Kekule, A.S., Lauer, U., Meyer, M., Caselmann, M.H., Hofschneider, P.H. & Koshy, R. (1990), The preS/S region of integrated hepatitis B virus encodes a transcriptional transactivator. Nature, 343, 457-461.
20. Kew, M.C., Geddes, E.W., Macnab, G.M. & Bersohn, I. (1974), Hepatitis B antigen and cirrhosis in Bantu patients. Cancer, 34, 539-541.
21. Kew, M.C. (1994), Hepatitis C virus and hepatocellular carcinoma. FEMS Microbiol. Rev., 14, 211-220.
22. Kew, M.C. (1996a), Hepatitis Delta virus and hepatocellular carcinoma. Vir. Hepatit. Rev., 2, 285-290.
23. Kew, M.C. (1996b), Hepatitis B and C viruses and hepatocellular carcinoma. Clin. Lab. Med., 16, 395-406.
24. Kew, M.C. (1997), Increasing evidence that hepatitis B virus X gene protein and p53 protein may interact in the pathogenesis of hepatocellular carcinoma. Hepatology, 25, 1037-1038.
25. Kew, M.C., Yu, M.C., Kedda, M-A., Coppin, A., Sarkin, A. & Hodkinson, J. (1997), The relative roles of hepatitis B and C viruses in the etiology of hepatocellular carcinoma in southern African blacks. Gastroenterology, 112, 184-187.
26. Kim, C.M., Koike, K., Saito, I., Miyamura, T. & Jay, G. (1991), HBx gene of hepatitis B virus induces liver cancers in transgenic mice. Nature, 351, 317-320.
27. Kin, D.W., Suzuki, R., Harada, T., Saito, I. & Miyamura, T. (1994), Trans-suppression of gene expression by hepatitis C virus core protein. Jpn. J. Med. Sci. Biol., 47, 211-220.
28. Kubo, S., Kinoshita, H., Horohashi, K., Tanaka, H., Tsukumoto, T., Shuto, T. & Kuroki, T. (1997), High malignancy of hepatocellular carcinoma in alcoholic patients with hepatitis C virus. Surgery, 121, 425-429.
29. Leon, M. & Kew, MC. (1995), Analysis of ras gene mutations in hepatocellular carcinoma in southern African blacks. AntiCancer. Res., 15, 859-862.
30. Lightfoot, K., Skelton, M., Kew, M.C., Yu, M.C., Kedda, M-A., Coppin, A. & Hodkinson, JH. (1997), Does Hepatitis GB virus C infection cause hepatocellular carcinoma in black Africans? Hepatology, 26, 740-742.
31. Matsubara, K. & Tokino, T. (1990), Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis. Mol. Biol. Med., 7, 243-260.
32. Mazzella, G., Accogli, E., Sottili, S., Festi, D., Orsini, M., Salzetta, A., Novelli, V., Cipoola, A., Fabbri, C., Pezzola, A. & Roda, E. (1996), α-interferon treatment may prevent hepatocellular carcinoma in HCV-related cirrhosis. Hepatology, 24, 141-147.
33. Nishiguchi, S., Kuroki, T., Nakatani, S., Morimoto, H., Takeda, T., Nakajima, S., Shiomi, S., Seki, S., Kobayashi, K. & Otani, S. (1995), Randomised trial of effects of interferon-α on incidence of hepatocellular carcinoma in chronic active hepatitis C with cirrhosis. Lancet, 346, 1051-1055.
34. Paterlini, P., Poussin, K., Kew, M.C., Franco, D. & Brechot, C. (1993), Selective accumulation of the X transcript of hepatitis B virus in patients negative for hepatitis B surface antigen with hepatocellular carcinoma. Hepatology, 21, 313-321.
35. Popper, H., Roth, L., Purcell, R.H., Tennant, B.C. & (1987), Gerin, J. Hepatocarcinogenicity of the woodchuck hepatitis virus. Proc. Natl. Acad. Sci. USA, 84, 866-870.
36. Prince, A.M., Szmunesss, W., Michon, J., Demaille, J., Diebolt, G., Linhard, J., Quenum, C. & Sankale, M. (1975), A case/control study of the association between primary liver cancer and hepatitis B infection in Senegal. Int. J. Cancer, 376-383.
37. Rogler, C.E., Sherman, M., Shafritz, D.A., Summers, J., Shows, T.B., Henderson, A. & Kew, M.C. (1985), Deletion in chrosome 11p associated with hepatitis B virus integration site. Science, 230, 319-322.
38. Roudot-Thoroval, F., Bastie, A., Pawlotsky, J.M. & Dhumeaux, D. (1997), Epidemiological factors affecting the severity of HCV-related liver disease: A French survey of 6664 patients. Hepatology, 26, 485-494.
39. Sakamura, D., Furakawa, T. & Takegami, T. (1995), Hepatitis C virus non-structural protein NS3 transforms NIH 3T3 cells. J. Virol., 69, 3893-3896.
40. Sato, A., Kato, Y., Nakata, K., Kazuhiko, N., Daikoku, M., Ishii, N., Matsumoto, T., Iseti, K., Mazume, H. & Nagataki, S. (1996), Relationship between sustained elevation of serum alanine aminotransferase and progression from cirrhosis to hepatocellular carcinoma: Comparison in patients with hepatitis B virus and hepatitis C virus-associated cirrhosis. J. Gastroenterol. Hepatol., 11, 944-948.
41. Shafritz, D.A. & Kew, M.C. (1981), Identification of integrated hepatitis B virus DNA sequences in human hepatocellular carcinoma. Hepatology, 1, 1-8.
42. Shih, C-M., Lo, S.J., Miyamura, T., Chen, S-Y., & Lee, Y-HW. (1993), Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein HUH-7 cells. J. Virol., 67, 5823-5832.
43. Shirakata, Y., Kawada, M., Fujiki, Y., Sano, H., Oda, M., Yaginuma, K., Kobayashi, M. & Koike, K. (1989), The X gene of hepatitis B virus induced growth stimulation and tumorigenic transformation in mouse NIH 3T3 cells. Jpn. J. Cancer. Res., 80, 617-621.
44. Silini, E., Bottelli, R., Asti, M., Bruno, S., Candusso, M.E., Brambilla, S., Bono, F., Iamoni, G., Tinelli, C., Mondelli, M.U. & Ideo, G. (1996), Hepatitis C virus genotypes and risk of hepatocellular carcinoma in cirrhosis: a case-control study. Gastroenterology, 11, 199-205.
45. Simonetti, R.G., Camma, C., Fiorello, F., Cottone, M., Rapicetta, M., Marino, L., Fiorentino, G., Craxi, A., Ciccaglione, A., Giuseppetti, R., Stroffolini, T. & Pagliari, L. (1992), Hepatitis C virus infection as a risk factor for hepatocellular carcinoma in patients with cirrhosis. Ann. Intern. Med., 116, 97-102.
46. Slagle, B.L., Lee, T-H. & Butel, J.S. (1992), Hepatitis B virus and hepatocellular carcinoma. Prog. Med. Virol., 39, 167-203.
47. Takano, S., Yokosuka, O., Imazeki, F., Tagawa, M. & Omata, M. (1995), Incidence of chronic hepatitis B and C: A prospective study of 251 patients. Hepatology, 21, 650-655.
48. Truant, R., Antunovic, J., Greeblatt, J., Prives, C. & Cromlish, J.A. (1995), Direct interaction of the hepatitis B virus HBX with p53 protein leads to the inhibition by HBX of p53 response element-directed transactivation. J. Virol., 69, 1851-1859.
49. Tsai, S-L., Liaw, Y-F., Yen, C-T. & Kuo, G. (1995), Cellular immune responses in patients with dual infection with hepatitis B and C viruses: Dominant role of hepatitis C. Hepatology, 21, 908-912.
50. Tsukuma, H., Hiyama, T., Tanaka, S., Nakao, M., Yabuchi, T., Kitamura, T., Nakanishi, K., Fujimoto, I., Inoue, A., Yamzaki, H. & Kawashima, T. (1993), Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N. Engl. J. Med., 328, 1797-1801.
51. Ueda, H., Ulrich, S.J., Gangemi, J.D., Kappel, C.A., Ngol, L., Feitelsohn, M.A. & Jay, G. (1995), Functional inactivation but not structural mutation of p53 causes liver cancer. Nat. Genet., 9, 41-47.
52. Unsal, H., Zakicier, C., Marcais, C., Kew, M.C., Volkmann, M., Zentgraf, H., Isselbacher, K. & Ozturk, M. (1994), Genetic heterogeneity of hepatocellular carcinoma. Proc. Natl. Acad. Sci. USA, 91, 822-826.
53. Wang, J.C. (1985), DNA topoisomerases. Ann. Biochem., 54, 665-697.
54. Wang, X.W., Forrester, K., Yeh, G.H., Feitelsohn, M.A., Gu, J-R. & Harris, C.C. (1994), Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3. Proc. Natl. Acad. Sci. USA, 91, 2230-2234.
55. Wang, X.W., Yeh, H., Schaeffer, L., Roy, R., Moncollin, V., Egly, J-M., Wang, Z., Friedberg, E.C., Evans, MK. & Taffe B.G. (1995a), p53 modulation of TFIIH-associated nucleotide excision repair activity. Nat. Genet., 10, 188-195.
56. Wang, X.W., Gibson, M.K., Vermeulen, W., Yeh, H., Forrester, K., Sturzbecher, H-W., Hoeijmakers, J.H.J. & Harris, C.C. (1995b), Abrogation of p53-induced apoptosis by the hepatitis B virus X gene. Cancer Res., 55, 6012-6016.
57. Zein, N.N., Poteruch, J., Gross, J.B., Wiesner, R.H., Therneau, T.M., Gossard, A.A., Wendt, N.K., Mitchell, P.S., Germer, J.J. & Persing, D.H. (1996), Increased risk of hepatocellular carcinoma in patients infected with hepatitis C genotype 1b. Am. J. Gastroenterol., 12, 1560-1562.