The management dilemma of the mildly abnormal smear: Fact or fiction?

Annals of the Academy of Medicine Singapore

Volumn 27, Issue 5, 1998, Pages 666-670

  Jones, M H ^a  

^a Gravesend and North Kent Hospital   (United Kingdom)

Author keywords

Clinical outcome; Management options; Mild dyskaryosis; Solution

Indexed keywords

COLPOSCOPY; DISEASE MANAGEMENT; FEMALE; HUMAN; MASS SCREENING; PATIENT REFERRAL; REVIEW; RISK FACTOR; UNITED KINGDOM; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR; VAGINA SMEAR;

CERVICAL INTRAEPITHELIAL NEOPLASIA; COLPOSCOPY; DISEASE MANAGEMENT; FEMALE; GREAT BRITAIN; HUMANS; MASS SCREENING; REFERRAL AND CONSULTATION; RISK FACTORS; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 0032153098     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Cervical Screening. UK: NHSCSP Publication No. 7, 1997.
2. Robertson A J, Anderson J H, Swanson Beck J, Burnett R A, Howarson S R, Lee F D, et al. Observer variability in histopathological reporting of cervical biopsy specimens. J Clin Pathol 1989; 42:231-8.
3. Richart R M, Wright T C. Controversies in the management of low-grade cervical intraepithelial neoplasia. Cancer 1993; 71:1413-21.
4. Smith A, Elkind A, Eardley A. Making cervical screening work. BMJ 1989; 298:1662-4.
5. Robertson J H, Woodend B. Elliott H. Cytological changes preceding cervical cancer. J Clin Pathol 1994; 47:278-9.
6. Jarmulowicz M R, Jenkins D, Barton S E, Goodall A L, Hollingworth A, Singer A. Cytological status and lesion size: a farther dimension in cervical neoplasia. Br J Obstet Gynecol 1989; 96:1061-6.
7. Walker E M, Dodgson J, Duncan I D. Does mild atypia on a cervical smear warrant further investigation? Lancet 1986; 3:376-88.
8. Mclndoe W A, Mclean M R, Jones R N, Mullins P R. The invasive potential of carcinoma in situ of the cervix. Obstet Gynecol 1984; 64:451-9.
9. Tilbury P, Singer A, Jenkins D. CIN 3: the role of lesion size in invasion. Br J Obstet Gynecol 1992; 99:583-6.
10. Robertson J H, Woodend B E, Grazier E H, Hutchinson J. Risk of cervical cancer associated with mild dyskaryosis. BMJ 1988; 297:18-21.
11. Austoker J. Screening for cervical cancer. BMJ 1994; 309:241-8.
12. Jones M H, Jenkins D, Cuzick J, Wolfendale M R, Jones J J, Balogun-Lynch C, et al. Mild cevical dyskaryosis: safety of Cytological surveillance. Lancet 1992; 339:1440-3.
13. Shafi M I. Management of women with mild dyskaryosis. BMJ 1994; 309:590-1.
14. Posner T, Vessey M. Prevention of cervical cancer: the patient's view. London: Kings Fund, 1988.
15. Jones M H, Jenkins D, Singer A. The mildly dyskaryotic smear: is patient anxiety related to choice of management? J R Soc Med 1996; 89:257-60.
16. Luesley D M, Cullimore J, Redman C W, Lawton F G, Emens J M, Rollason T P, et al. Loop diathermy excision of the cervical transformation zone in patients with abnormal cervical smears. BMJ 1990; 300:1690-3.
17. Sedlacek T V. Clinical options in dealing with minor cytologic abnormalities. The Colposcopist 1992; 14:1-2.
18. Jones M H, Jenkins D, Singer A. The cost of detecting high grade precancer in women with mild dyskaryosis - a cost minimisation analysis. Paper presented at the British Society of Colposcopy and Cervical Pathology Annual Meeting; 1997 April; Glasgow.
19. Flannelly G, Anderson D, Kitchener H C, Mann E M, Campbell M, Fisher P, et al. Management of women with mild and moderate cervical dyskaryosis. BMJ 1994; 308:1399-403.
20. Jones M H, Jones J J. Colposcopy is not cost effective [letter]. BMJ 1994; 309:268.
21. Macgregor J E, Campbell M K, Mann E M F, Swanson K Y. Screening for cervical intraepithelial neoplasia in north east Scotland shows fall in incidence and mortality from invasive cancer with concomitant rise in preinvasive disease. BMJ 1994; 308:1407-11.
22. Bavin P J, Giles J A, Deery A, Crow J, Griffiths P D, Emery V C, et al. Use of semi-quantitative PCR for human papillomavirus DNA type 16 to identify women with high grade cervical disease in a population presenting with a mildly dyskaryotic smear report. Br J Cancer 1993; 67:602-5.
23. Cuzick J, Terry G, Ho L, Hollingworth T, Anderson M. Type-specific human papillomavirus DNA in abnormal smears as a predictor of high-grade cervical intraepithelial neoplasia. Br J Cancer 1995; 71:206-9.
24. Luesley D, Blomfield P, Dunn J, Shafi M, Chenoy R, Buxton J. Cigarette smoking and histological outcome in women with mildly dyskaryotic cervical smears. Br J Obstet Gynecol 1994; 101:49-52.
25. Jones M H, Jones J J, Jenkins D. Cigarette smoking and histological outcome in women with mildly dyskaryotic cervical smears. Br J Obstet Gynecol 1994; 101:927-8.
26. Blomfield P I, Lancashire R J, Woodman C B J. Can women at risk of cervical abnormality be identified? Br J Obstet Gynaecol 1998; 105:486-92.
27. Sherlaw-Johnson C, Gallivan S, Jenkins D, Jones M H. Cytological screening and management of abnormalities in prevention of cervical cancer; an overview with stochastic modelling. J Clin Pathol 1994; 47:430-5.
28. Jones M H, Jenkins D, Singer A. Regular audit of colposcopic biopsies from women with a mildly dyskaryotic or borderline cervical smear results in fewer cases of CIN 3. Cytopathology 1996; 7:17-24.
29. Herrington C S, Evans M F, Haliam F M, Gray W, McGee J. Human papilloma virus state in the prediction of high-grade cervical intraepithelial neoplasia in patients with persistant low-grade cervical cytological abnormalities. Br J Cancer 1995; 71:206-9.
30. Jones M H. The management dilemma of mild dyskaryosis [letter]. Cytopathology October 1998 (In press).