Efficacy and acceptability of two monophasic oral contraceptives containing ethinylestradiol and either desogestrel or gestodene

European Journal of Contraception and Reproductive Health Care

Volumn 3, Issue 3, 1998, Pages 113-120

  Halbe, H W ^a,h   De Melo, N R ^a   Bahamondes, L ^b   Petracco, A ^c   Lemgruber, M ^d   De Andrade, R P ^e   Da Cunha, D C ^f   Guazelli, C A F ^g   Baracat, E C ^g  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d PONTIFICAL CATHOLIC UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^e FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^f Department of Gynecology and Obstetrics   (Brazil)

^g FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^h Hospital São Paulo ^*  (Brazil)

Author keywords

Acceptability; Desogestrel; Efficacy; Gestodene; Oral contraceptive

Indexed keywords

DESOGESTREL; ESTRADIOL DERIVATIVE; ETHINYLESTRADIOL; GESTODENE; ORAL CONTRACEPTIVE AGENT; PREGNANE DERIVATIVE; PROGESTERONE DERIVATIVE;

ACNE VULGARIS; ADULT; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; BRAZIL; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HOSPITALIZATION; HUMAN; MENSTRUAL CYCLE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; UTERUS BLEEDING;

ACNE VULGARIS; ADULT; BLOOD PRESSURE; BODY WEIGHT; BRAZIL; CONTRACEPTIVES, ORAL, COMBINED; CONTRACEPTIVES, ORAL, SYNTHETIC; DESOGESTREL; ESTRADIOL CONGENERS; ETHINYL ESTRADIOL; FEMALE; HUMANS; MENSTRUAL CYCLE; NORPREGNENES; PROGESTERONE CONGENERS; SEVERITY OF ILLNESS INDEX; UTERINE HEMORRHAGE;

EID: 0032151995     PISSN: 13625187     EISSN: None     Source Type: Journal    
DOI: 10.3109/13625189809051413     Document Type: Article

References (14)

1. Newton JR. Classification and comparison of oral contraceptives containing new generation progestogens. Hum Reprod Update 1995; 1: 231-63
2. Rekers H. Multicenter trial of a monophasic oral contraceptive containing ethinyl estradiol and desogestrel. Acta Obstet Gynecol Scand 1988; 67: 171-4
3. Notelovitz M. Contraceptive efficacy and safety of a monophasic oral contraceptive containing 150 μg desogestrel and 30 μg ethinyl estradiol: United States clinical experience using a 'Sunday start' approach. Fertil Steril 1995; 64: 261-6
4. Fotherby K. Oral contraceptives, lipids and cardiovascular disease. Contraception 1985; 31: 367-94
5. Wilde MI, Balfour JA. Gestodene. A review of its pharmacology, efficacy and tolerability in combined contraceptive preparations. Drugs 1995; 50: 364-95
6. Halbe HW, Cunha DC, Diaz J, et al. Clinical experience in Brazil with a desogestrel-containing oral contraceptive. In Halbe HW, Rekers H, eds. Oral Contraception into the 1990s. Carnforth, UK: Parthenon Publishing, 1989: 69-74
7. Brill K, Müller C, Schnitker J, Albring M. The influence of different modern low-dose oral contraceptives on intermenstrual bleeding. Adv Contracept 1991; 7(Suppl 2): 51-61
8. Latin American Oral Contraceptive Study Group. Clinical comparison of monophasic oral contraceptive preparations of gestodene/ethinyl estradiol and desogestrel/ethinyl estradiol. Contraception 1994; 50: 201-14
9. Zichella L, Sbrignadello C, Tomassini A, et al. Open comparative study on the efficacy and acceptability of two new monophasic oral contraceptives. In Keller PJ, Sirtori C, eds. Contraception into the Next Decade. Carnforth, UK: Parthenon Publishing, 1988: 33-41
10. Benagiano G. Comparison of two monophasic oral contraceptives: gestodene/ethinyl estradiol versus desogestrel/ethinyl estradiol. Int J Fertil 1989;34(Suppl): 31-9
11. Koetsawang S, Charoenvisal C, Banharnsupawat L, Singhakovin S, Kaewsuk O, Punnahitanont S. Multicenter trial of two monophasic oral contraceptives containing 30 meg ethinylestradiol and either desogestrel or gestodene in Thai women. Contraception 1995;51:225-9
12. Janowitz B, Kane TT, Arruda JM, Covington DL, Morris L. Side effects and discontinuation of oral contraceptive use in Southern Brazil. J Biosoc Sci 1986; 118: 261-71
13. Bilotta P, Favilli S. Clinical evaluation of a monophasic ethinylestradiol/desogestrel-containing oral contraceptive. Arzneimittelforschung 1988; 38: 932-4
14. Mango D, Ricci S, Manna P, Miggiano GAD, Serra GB. Clinical and hormonal effects of ethinylestradiol combined with gestodene and desogestrel in young women with acne vulgaris. Contraception 1996; 53: 163-70