Overexpression of CuZnSOD gene suppresses the growth of hepatocellular cancer cell line HepG2

Chinese Medical Journal

Volumn 111, Issue 9, 1998, Pages 789-792

  Bai, Jingxiang ^a   Zhu, Xueguang ^a   Zheng, Xincheng ^a   Wu, Yijing ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

SUPEROXIDE DISMUTASE;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; PATHOLOGY; RETROVIRUS;

CARCINOMA, HEPATOCELLULAR; CELL DIVISION; GENE EXPRESSION; HUMANS; LIVER NEOPLASMS; RETROVIRIDAE; SUPEROXIDE DISMUTASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032149060     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Guyton KZ, Kensler TW. Oxidative mechanisms in carcinogenesis. Br Med Bull 1993; 49: 523.
2. Emerit I. Reactive oxygen species, chromosome mutation, and cancer: possible role of clastogenic factors in carcinogenesis. Free Radic Biol Med 1994; 16: 99.
3. Bravard A, Sabatier L, Hoffshir F, et al. SOD2: a new type of tumor suppressor gene? Int J Cancer 1992; 51: 476.
4. Church SL, Grant JW, Ridnour LA, et al. Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc Natl Acad Sci U S A 1993; 90: 3113.
5. Li J-J, Oberley LW, St Clair DK, et al. Phenotypic changes induced in human breast cancer cells by overexpression of manganese-containing superoxide dismutase. Oncogene 1995; 10: 1989.
6. Zheng XC, An W, Wu YJ. Recombination of retroviral vector containing human CuZnSOD gene. J Beijing Med Univ 1997; 2: 112.
7. Yan T, Oberley LW, Zhong WX, et al. Manganese-containing peroxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts. Cancer Res 1996; 56: 2864.