Selecting ethanol as a model organic solvent in radiation chemistry-3. Radiolysis of glycyrrhetinic acid (GL)-ethanol system and structure modification of GL by γ radiation method

Radiation Physics and Chemistry

Volumn 53, Issue 2, 1998, Pages 151-160

  Chen, Chang ^a   He, Yongke ^a   Wu, Jilan ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Ethanol radiation; Glycyrrhetinic acid; Licorice; Olean 29 oic acid,3 hydroxy 11 oxo 12 ethoxyl 13 hydro ,(3 , 20 ) ; Structure modification

Indexed keywords

CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; ETHANOL; GAMMA RAYS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; ORGANIC ACIDS; ORGANIC SOLVENTS; STRUCTURE (COMPOSITION); ULTRAVIOLET SPECTROSCOPY;

GLYCYRRHETINIC ACID; RADIOLYSIS; STRUCTURE MODIFICATION;

RADIATION CHEMISTRY;

ALCOHOL; GLYCYRRHETINIC ACID; ORGANIC SOLVENT;

ARTICLE; GLYCYRRHIZA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; RADIOLYSIS; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET RADIATION;

EID: 0032146819     PISSN: 0969806X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-806X(98)00007-3     Document Type: Article

References (11)

1. Fletcher J.W., Richards P.J., Seddon W.A. Pulse radiolysis of liquid ethanol: reaction kinetics of the radicals. Can. J. Chem. 48:1970;3765-3768.
2. Gilbert R.J., James K.C. Preparation and surface-active properties of glycyrrhizic acid and its salts. J. Pharm. Pharmacol. 16:1964;394-399.
3. Jin H.F., Wu J.L.et al. Selecting ethanol as a model organic solvent in radiation chemistry. 1. Radiolysis of acetone-ethanol system. Radiat. Phys. Chem. 47(4):1996;555-558.
4. Li X.X., Wen W.X. Preparation and medicinal use of glycyrrhizic acid and its derivatives. Chin. J. Pharm. 24(10):1993;475-478.
5. Nakashima H.et al. A new anti-human immune-deficiency virus substance, glycyrrhizin sulfate: Endowment of glycyrrhizin with reverse transcriptase-inhibitory activity by chemical modification. Jpn. J. Cancer Res. 78:1987;767-771.
6. Shibata S.et al. Chemical modification of glycyrrhetinic acid in relation to the biological activities. Chem. Pharm. Bull. 35(5):1987;1910-1918.
7. Takahashi K.et al. Chemical modification of glycyrrhetinic acid in relation to the biological activities. Chem. Pharm. Bull. 28(11):1980;3449-3452.
8. Vora, P.S., 1982. High pressure liquid chromatographic determination of glycyrrhizic acid or glycyrrhizic acids salts in various licorice products: collaborative study. J. Assoc. Off. Anal. Chem. 65, No. 3, 452 - 454.
9. Wang Q.H.et al. Extraction, separation and purification of glycyrrhizic acid from licorice and glycyrrhiza extract. Pharm. Ind. 18(11):1987;481-484.
10. Wardman P.et al. Radiation chemistry applied to drug design. Int. J. Radiat. Biol. 65(1):1994;35-41.
11. Wu, J.L., Qi, S.C., 1993. Radiation Chemistry. Atomic Energy Press, Beijing, China.