Embryonic rat hippocampal neurons and GAB(A), receptor subunit-transfected non-neuronal cells release GABA tonically

Journal of Membrane Biology

Volumn 164, Issue 3, 1998, Pages 239-251

  Valeyev, A Y ^a,c   Schaffner, A E ^a   Skolnick, P ^b,d   Dunlap, V S ^a,e   Wong, G ^b,f   Barker, J L ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d ELI LILLY AND COMPANY   (United States)

^e EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^f UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Embryonic rat; GABA; GABA(A) receptor Cl channels; Hippocampus; Patch clamp

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; BICUCULLINE; ION CHANNEL; PICROTOXIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EMBRYO; HIPPOCAMPUS; MEMBRANE CURRENT; MEMBRANE STEADY POTENTIAL; MORPHOLOGY; NERVE CELL; NONHUMAN; PATCH CLAMP; POSTNATAL DEVELOPMENT; RAT;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0032146813     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002329900409     Document Type: Article

References (22)

1. - conductances activated by GABA in cultured mammalian central neurons. In: Chloride Channels and Carriers in Nerve Muscle and Glial Cells. F.J. Alvarez-Leefmans and J.M. Russell, Editors. pp. 273-297. Plenum Press, New York
2. Barker, J.L., Behar, T., Li, Y.-X., Liu, Q.-Y., Ma, W., Maric, D., Maric, I., Schaffner, A.E., Serafini, R., Smith, S.V., Somogyi, R., Vautrin, J., Wen, X.-L., Xian, H. 1998. GABAergic cells and signals in CNS development. Perspectives on Development Neurobiology (in press)
3. Ben-Ari, Y., Cherubini, E., Corradetti, A.R., Gaiarsa, J.L. 1989. Giant synaptic potentials in immature rat CA3 hippocampal neurons. J. Physiol. 416:303-325
4. Bormann, J., Hamill, O.P., Sakmann, B. 1987. Mechanism of anion permeation through channels gated by glycine and γ-aminobutyric acid in mouse cultured spinal neurones. J. Physiol. 385:243-286
5. Cherubini, E., Rovira, C., Gaiarsa, J.L., Corradetti, R., Ben-Ari, Y. 1990. GABA mediated excitation in immature rat CA3 hippocampal neurons. Int. J. Der. Neurosci. 8:481-490
6. Esclapez, M., Tillakaratne, N.J.K., Kaufman, D.E., Tobin, A.J., Houser, C.R. 1994. Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms. J Neuroscience 14:1834-1855
7. Hell, J.W., Edelman, E., Hartinger, J., Jahn, R. 1990. Functional reconstitution of the γ-aminobutyric acid transporter from synaptic vesicles using artificial ion gradients. Biochemistry 30:11795-11800
8. Houser, C.R., Esclapez, M. 1994. Localization of mRNAs encoding two forms of glutamic acid decarboxylase in the rat hippocampal formation. Hippocampus 4:530-545
9. Huettner, J.E., Baughman, R.W. 1986. Primary culture of identified neurons the cortex of postnatal rats. J. Neurosci. 6:3044-3060
10. - channels in cultured embryonic rat thalamic neurons. J. Membrane Biol. 145:279-284
11. A current by astrocytes in cultured embryonic rat hippocampal neurons. J. Neuroscience 16:2912-2923
12. Neher, E., Stevens, C.F. 1977. Conductance fluctuations and ionic pores in membranes. Ann. Rev. Biophys. Bioenerg. 6:345-381
13. Otis, T.A., Staley, K.J., Mody, I. 1991. Perpetual inhibitory activity in mammalian brain slices generated by spontaneous GABA release. Brain Res. 545:142-150
14. Rozenberg, F., Robin, O., Jardin, L., Ben-Ari, Y. 1989. Distribution of GABAergic neurons in late fetal and early postnatal rat hippocampus. Dev. Brain Res. 50:177-187
15. Segal, M. 1983. Rat hippocampal neurons in culture: Responses to electrical and chemical stimuli. J. Neurophysiol. 50:1249-1264
16. - ion conductance. J Neurophysiol. 51:500-515
17. Segal, M., Barker, J.L. 1984b. Rat hippocampal neurons in culture: Voltage clamp analysis of inhibitory synaptic connections. J. Neurophysiol. 52:469-487
18. - channels are randomly activated by continuous GABA secretion in cultured embryonic rat hippocampal neurons. Neurosci. Lett. 155:199-203
19. Vautrin, J., Schaffner, A.E., Barker, J.L. 1992. Two classes of spontaneous GABA-mediated miniature synaptic currents in cultured rat hippocampal neurons. Neurosci. Lett. 138:67-71.
20. 2+ into quantal release. Neurosci. Lett. 158:125-129
21. - conductance in cultured rat hippocampal neurons. J. Physiol. 479:53-63
22. A/benzodiazepine receptors in a transfected cell line. Mol. Pharmacol. 42:996-1003