An upstream regulatory element containing two nine basepair repeats regulates expression of the Entamoeba histolytica hgl5 lectin gene

Molecular and Biochemical Parasitology

Volumn 94, Issue 2, 1998, Pages 309-313

  Schaenman, Joanna M ^a   Driscoll, Priscilla C ^a   Hockensmith, Joel W ^a   Mann, Barbara J ^a   Petri Jr , William A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Amebiasis; Entamoeba histolycita hgl5; Lectin gene

Indexed keywords

LECTIN; VIRULENCE FACTOR;

AMEBIASIS; ARTICLE; DNA FLANKING REGION; ENTAMOEBA HISTOLYTICA; GENE EXPRESSION REGULATION; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE;

ANIMALS; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); ENTAMOEBA HISTOLYTICA; GENES, PROTOZOAN; LECTINS; PROTOZOAN PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; REPETITIVE SEQUENCES, NUCLEIC ACID; TRANS-ACTIVATION (GENETICS); VIRULENCE;

ENTAMOEBA; ENTAMOEBA HISTOLYTICA; PROTOZOA;

EID: 0032145901     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00081-4     Document Type: Article

References (10)

1. World Health Organization. The World Health Report 1995: Bridging the Gaps. Report of the Director-General. Geneva: World Health Organization, 1995.
2. Petri WA Jr Amebiasis and the Entamoeba histolytica Gal/GalNAc lectin: from lab bench to bedside. J Invest Med. 44:1996;24-35.
3. Petri WA Jr, Smith RD, Schlesinger PH, Murphy CF, Ravdin JI Isolation of the galactose binding lectin of Entamoeba histolytica. J Clin Invest. 80:1987;1238-1244.
4. Purdy JE, Pho LT, Mann BJ, Petri WA Jr Upstream regulatory elements controlling expression of the Entamoeba histolytica lectin. Mol Biochem Parasitol. 78:1996;91-103.
5. Singh U, Rogers JB, Mann BJ, Petri WA Jr Transcription initiation is controlled by three core promoter elements in the hgl5 gene of the protozoan parasite Entamoeba histolytica. Proc Natl Acad Sci USA. 94:1997;8812-8817.
6. Vines RR, Purdy JE, Ragland BD, Samuelson J, Mann BJ, Petri WA Jr Stable transfection of Entamoeba histolytica. Mol Biochem Parasitol. 71:1995;265-267.
7. Mitchell PJ, Tjian R Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science. 245:1989;371-378.
8. Christensen J, Cotmore SF, Tattersall P Parvovirus initiation factor PIF: a novel human DNA-binding factor which coordinately recognizes two ACGT motifs. J Virol. 71:1997;5733-5741.
9. Gilchrist CA, Mann BJ, Petri WA Jr Control of ferredoxin and Gal/GalNAc lectin gene expression in Entamoeba histolytica by a cis-acting DNA sequence. Infect Immun. 66:1998;2383-2386.
10. Hockensmith JW, Kubasek WL, Vorachek WR, von Hippel PH Laser cross-linking of proteins to nucleic acids. J Biol Chem. 268:1993;15712-15720.