A potential anti-asthmatic drug, CR 2039, enhances the anticonvulsive activity of some antiepileptic drugs against pentetrazol in mice

European Neuropsychopharmacology

Volumn 8, Issue 3, 1998, Pages 233-238

  Czuczwar, S J ^a   Gasior, M ^a   Kozicka, M ^a   Pietrasiewicz, T ^a   Turski, W A ^a   Kleinrok, Z ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Clonazepine; CR 2039; Ethosuximide; Seizures; Valproate

Indexed keywords

4 (1H TETRAZOL 5 YL) N [(1H TETRAZOL 5 YL)PHENYL]BENZAMIDE; ANDOLAST; ANTIASTHMATIC AGENT; ANTICONVULSIVE AGENT; CLONAZEPAM; ETHOSUXIMIDE; PENTETRAZOLE; UNCLASSIFIED DRUG; VALPROATE MAGNESIUM;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

EID: 0032145594     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-977X(97)00077-1     Document Type: Article

References (28)

1. Ault B., Olney M.A., Joyner L.J., Boyer C.E., Notrica C.A., Soroko F.E., Wang C.M. Proconvulsant actions of theophylline and caffeine in the hippocampus: implications for the management of temporal lobe epilepsy. Brain Res. 426:1987;93-102.
2. Boissier J.R., Tardy J., Diverres J.C. Une nouvelle méthode simple pour explorer l'action 'tranquilisante': le test de la cheminée. Med. Exp. (Basel). 3:1960;81-84.
3. Boast C.A., Bernard P.S., Barbaz B.S., Bergen K.M. The neuropharmacology of various diazepam antagonists. Neuropharmacology. 22:1983;1511-1521.
4. Borowicz K.K., Kozicka M., Kleinrok Z., Czuczwar S.J. Influence of aminophylline and 8-(p-sulfophenyl)theophylline on the anticonvulsive action of diphenylhydantoin, phenobarbital, and valproate against maximal electroshock-induced convulsions in mice. J. Neural Transm. 93:1993;157-163.
5. Borowicz K.K., Gasior M., Kleinrok Z., Czuczwar S.J. The non-competitive AMPA/kainate receptor antagonist, GYKI 52466, potentiates the anticonvulsant activity of conventional antiepileptics. Eur. J. Pharmacol. 281:1995;319-326.
6. Chang, T., 1989. Ethosuximide. Absorption, distribution, and excretion. In: Levy, R., Mattson, R., Meldrum, B., Pentry, J.K., Dreifuss, F.E. (Eds.), Antiepileptic Drugs. Raven Press, New York, pp. 671-678.
7. Chu N.-S. Caffeine- and aminophylline-induced seizures. Epilepsia. 22:1981;85-94.
8. Czechowska G., Dziki M., Pietrasiewicz T., Kleinrok Z., Turski W.A., Czuczwar S.J. Competitive antagonists of NMDA receptors, CGP 37849 and CGP 39551, enhance the anticonvulsant activity of valproate against electroconvulsions in mice. Eur. J. Pharmacol. 232:1993;59-64.
9. Czuczwar S.J., Turski W.A., Ikonomidou C., Turski L. Aminophylline and CGS 8216 reverse the protective action of diazepam against electroconvulsions in mice. Epilepsia. 26:1985;693-696.
10. Czuczwar S.J., Ikonomidou C., Kleinrok Z., Turski W.A. Effect of aminophylline on the protective action of common antiepileptic drugs against electroconvulsions in mice. Epilepsia. 27:1986;204-208.
11. Czuczwar S.J., Kleinrok Z., Turski L., Turski W.A. Effect of aminophylline and enprofylline on the protective efficacy of common antiepileptic drugs against electroconvulsions in mice. Epilepsia. 28:1987;383-386.
12. Czuczwar S.J., Janusz W., Szczepanik B., Wamil A., Kleinrok Z. Effect of aminophylline upon the protective activity of common antiepileptic drugs and their plasma levels in mice. Neurosci. Res. 6:1989;470-474.
13. Czuczwar S.J., Gasior M., Kozicka M., Pietrasiewicz T., Turski W.A., Kleinrok Z. Influence of a potential anti-asthmatic drug, CR 2039, upon the anticonvulsive activity of conventional antiepileptics against maximal electroshock-induced seizures in mice. J. Neural Transm. 103:1996;1371-1379.
14. Litchfield J.T., Wilcoxon F. A simplified method of evaluating dose-effect experiments. J. Pharmacol. Exp. Ther. 96:1949;99-113.
15. Löscher W., Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2:1988;145-181.
16. Pietrasiewicz T., Czechowska G., Dziki M., Turski W.A., Kleinrok Z., Czuczwar S.J. Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics. Eur. J. Pharmacol. 250:1993;1-7.
17. Revel L., Colombo S., Ferrari F., Folco G., Rovati L.C., Makovec F. CR 2039, a new bis-(1H-tetrazol-5-yl)phenylbenzamide derivative with potential for the topical treatment of asthma. Eur. J. Pharmacol. 229:1992;45-53.
18. Scherkl R., Hashem A., Frey H.-H. Histamine in brain - its role in regulation of seizure susceptibility. Epilepsy Res. 10:1991;111-118.
19. Singer E.P., Kolischenko A. Seizures due to aminophylline overdose. Chest. 87:1985;755-757.
20. Ukena, D., Sybrecht, R., 1990. Management of chronic airway obstruction: theophylline - is it still necessary? Lung (Suppl.) 127-134.
21. Venault P., Chapouthier G., De Carvalho L.P., Simiand J., Morre M., Dodd R.H., Rossier J. Benzodiazepines impair and beta-carbolines enhance performance in learning and memory task. Nature. 321:1986;864-866.
22. Wlaź P., Roliński Z., Kleinrok Z., Czuczwar S.J. Anticonvulsant activity of carbamazepine and diphenylhydantoin against maximal electroshock in mice chronically treated with aminophylline. J. Neural Transm. 89:1992;41-48.
23. Wlaź P., Roliński Z., Kleinrok Z., Czuczwar S.J. Influence of chronic aminophylline on the anticonvulsant efficacy of phenobarbital and valproate in mice. Epilepsia. 34:1993;385-389.
24. Wlaź P., Roliński Z., Kleinrok Z., Czuczwar S.J. Influence of chronic aminophylline on antielectroshock activity of diazepam and aminophylline-induced convulsions in mice. Pharmacol. Biochem. Behav. 49:1994;609-613.
25. Yarnell P.R., Chu N.-S. Focal seizures and aminophylline. Neurology. 25:1975;819-822.
26. Yokoyama H., Iinuma K. Histamine and seizures. Implications for the treatment of epilepsy. CNS Drugs. 5:1996;321-330.
27. Zwillich C.W., Sutton F.D., Neff T.A., Cohn W.M., Matthay R.A., Weinberger M.M. Theophylline-induced seizures in adults: correlation with serum concentrations. Ann. Intern. Med. 82:1975;784-787.
28. Żarnowski T., Kleinrok Z., Turski W.A., Czuczwar S.J. 2,3-Dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline enhances the protective activity of common antiepileptic drugs against maximal electroshock-induced seizures in mice. Neuropharmacology. 32:1993;895-900.