Nerve growth factor randuces process formation in meningeal cells: Implications for scar formation in the injured CNS

Journal of Neuroscience

Volumn 18, Issue 15, 1998, Pages 5714-5722

  Frisén, Jonas ^a   Risling, Mårten ^a   Korhonen, Laura ^b   Zirrgiebel, Ute ^c   Johansson, Clas B ^a   Cullheim, Staffan ^a   Lindholm, Dan ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Injury; Meningeal cells; NGF; P75; Regeneration; TrkA

Indexed keywords

NERVE GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CELL SUBPOPULATION; CELL SURVIVAL; ENZYME BINDING; FEMALE; IMMUNOREACTIVITY; NONHUMAN; PIA MATER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SCAR FORMATION; SPINAL CORD INJURY;

EID: 0032145443     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-15-05714.1998     Document Type: Article

References (19)

1. Bakhit C, Armanini M, Wong WLT, Bennet GL, Wrathall JR (1991) Increase in nerve growth factor-like immunoreactivity and decrease in choline acetyltransferase following contusive spinal cord injury. Brain Res 554:264-271.
2. Barbacid M (1995) Neurotrophic factors and their receptors. Curr Opin Cell Biol 7:148-155.
3. LNTR reduces NGF binding to TrkA on PC12 cells. Neuron 13:203-215.
4. Beck KD, Lamballe F, Klein R, Barbacid M, Schauwecker PE, McNeill TH, Finch CE, Hefti F, Day JR (1993) Induction of noncatalytic trkB neurotrophin receptors during axonal sprouting in the adult hippocampus. J Neurosci 13:4001-4014.
5. Bracken MB, Shepard MJ, Collins WF, Holford TR, Young W, Baskin DS, Eisenberg HM, Flamm E, Leo-Summers L, Maroon J, Marshall LF, Perot PL, Piepmeier J, Sonntag VKH, Wagner FC, Wilberger JE, Winn HR (1990) A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. New Engl J Med 322:1405-1411.
6. Cattaneo E, McKay R (1990) Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor. Nature 347:762-765.
7. Chandler CE, Parsons LM, Hosang M, Shooter EM (1984) A monoclonal antibody modulates the interaction of nerve growth factor with PC 12 cells. J Biol Chem 259:6882-6889.
8. Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156-159.
9. Colombo JA, Napp MI, Puissant V (1994) Leptomeningeal and skin fibroblasts: two different cell types? Int J Dev Neurosci 12:57-61.
10. Cordon-Cardo C, Tapley P, Jing S, Nanduri V, O'Rourke E, Lamballe F, Kovary K, Klein R, Jones KR, Reichardt LF, Barbacid M (1991) The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell 66:173-183.
11. Crowley C, Spencer SD, Nishimura MC, Chen KS, Pitts-Meek S, Armanini MP, Ling LH, McMahon SB, Shelton DL, Levinson AD, Phillips HS (1994) Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76:1001-1011.
12. Davies AM, Lee K-F, Jaenisch R (1993) p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron 11:565-574.
13. NTR. Curr Opin Neurobiol 7:413-418.
14. Ernfors P, Ibáñez CF, Ebendal T, Olson L, Persson H (1990) Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain. Proc Natl Acad Sci USA 87:5454-5458.
15. Frisén J, Verge VMK, Cullheim S, Persson H, Fried K, Middlemas DS, Hunter T, Hökfelt T, Risling M (1992) Increased levels of trkB mRNA and trkB protein-like immunoreactivity in the injured rat and cat spinal cord. Proc Natl Acad Sci USA 89:11282-11286.
16. Frisén J, Verge VMK, Fried K, Risling M, Persson H, Trotter J, Hökfelt T, Lindholm D (1993) Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous system. Proc Natl Acad Sci USA 90:4971-4975.
17. Funakoshi H, Frisén J, Barbany G, Timmusk T, Zachrisson O, Verge VMK, Persson H (1993) Differential expression of mRNAs for neurotrophins and their receptors following axotomy of the sciatic nerve. J Cell Biol 123:455-466.
18. Götz R, Kolbeck R, Lottspreich F, Barde Y-A (1992) Production and characterization of recombinant mouse neurotrophin-3. Eur J Biochem 204:745-749.
19. Hallböök F, Ibáñez CF, Persson H (1991) Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary. Neuron 6:845-858.