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1
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0031916982
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Adult cortical dynamics
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Gilbert CD. Adult cortical dynamics. Physiol Rev. 78:1998;467-485.
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(1998)
Physiol Rev
, vol.78
, pp. 467-485
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Gilbert, C.D.1
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2
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0002410860
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GABA neurons and their role in activity-dependent plasticity of adult primate visual cortex
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A. Peters, Rockland K.S. New York: Plenum Press
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Jones EG, Hendry SHC, DeFelipe J, Benson DL. GABA neurons and their role in activity-dependent plasticity of adult primate visual cortex. Peters A, Rockland KS. Cerebral Cortex. Primary Visual Cortex in Primates. 10:1994;61-140 Plenum Press, New York.
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Cerebral Cortex. Primary Visual Cortex in Primates
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Jones, E.G.1
Hendry, S.H.C.2
Defelipe, J.3
Benson, D.L.4
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3
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0030976432
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Local circuit neurons of macaque monkey striate cortex: IV. Neurons of laminae 1-3A
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Lund JS, Wu CQ. Local circuit neurons of macaque monkey striate cortex: IV. Neurons of laminae 1-3A. J Comp Neurol. 384:1997;109-126.
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(1997)
J Comp Neurol
, vol.384
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Lund, J.S.1
Wu, C.Q.2
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4
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0031008195
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Molecular and physiological diversity of cortical nonpyramidal cells
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of outstanding interest. This multidisciplinary investigation combined electrophysiological whole-cell recordings in slices of rat sensory - motor cortex with the simultaneous detection of mRNA encoding for three calcium-binding proteins (i.e. calbindin, parvalbumin and calretinin) and four neuropeptides (i.e. neuropeptide Y, vasoactive intestinal polypeptide, somatostatin, and cholecystokinin) using single-cell reverse transcription PCR. Three broad subpopulations of cortical cells were identified on the basis of correlations between firing properties (i.e. fast spiking, regular spiking, and irregular spiking) and biochemical co-expression patterns; however, within two of these (fast and regular spiking), the pattern of expression of the biochemical markers itself was complex. The expression of neuropeptides did not seem to be tightly correlated with either the firing pattern or a particular calcium-binding protein. The authors conclude that the full
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Cauli B, Audinat E, Lambolez B, Angulo MC, Ropert N, Tsuzuki K, Hestrin S, Rossier J. Molecular and physiological diversity of cortical nonpyramidal cells. of outstanding interest J Neurosci. 17:1997;3894-3906 This multidisciplinary investigation combined electrophysiological whole-cell recordings in slices of rat sensory - motor cortex with the simultaneous detection of mRNA encoding for three calcium-binding proteins (i.e. calbindin, parvalbumin and calretinin) and four neuropeptides (i.e. neuropeptide Y, vasoactive intestinal polypeptide, somatostatin, and cholecystokinin) using single-cell reverse transcription PCR. Three broad subpopulations of cortical cells were identified on the basis of correlations between firing properties (i.e. fast spiking, regular spiking, and irregular spiking) and biochemical co-expression patterns; however, within two of these (fast and regular spiking), the pattern of expression of the biochemical markers itself was complex. The expression of neuropeptides did not seem to be tightly correlated with either the firing pattern or a particular calcium-binding protein. The authors conclude that the full characterization of the elements comprising a homogeneous network may require additional parameters.
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(1997)
J Neurosci
, vol.17
, pp. 3894-3906
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Cauli, B.1
Audinat, E.2
Lambolez, B.3
Angulo, M.C.4
Ropert, N.5
Tsuzuki, K.6
Hestrin, S.7
Rossier, J.8
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5
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0016774583
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The origin of efferent pathways from the primary visual cortex, area 17, of the macaque monkey as shown by the retrograde transport of horseradish peroxidase
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Lund JS, Lund RD, Hendrickson AE, Fuchs AF. The origin of efferent pathways from the primary visual cortex, area 17, of the macaque monkey as shown by the retrograde transport of horseradish peroxidase. J Comp Neurol. 164:1975;287-304.
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J Comp Neurol
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Lund, J.S.1
Lund, R.D.2
Hendrickson, A.E.3
Fuchs, A.F.4
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6
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0023126795
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Local circuitry of identified projection neurons in cat visual brain slices
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Katz LC. Local circuitry of identified projection neurons in cat visual brain slices. J Neurosci. 7:1987;1223-1249.
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(1987)
J Neurosci
, vol.7
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Katz, L.C.1
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7
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0029990442
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Contributions of individual layer 6 pyramidal neurons to local circuitry in macaque primary visual cortex
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Wiser AK, Callaway EM. Contributions of individual layer 6 pyramidal neurons to local circuitry in macaque primary visual cortex. J Neurosci. 16:1996;2724-2739.
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(1996)
J Neurosci
, vol.16
, pp. 2724-2739
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Wiser, A.K.1
Callaway, E.M.2
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8
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0342617726
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Intracortical axonal projections of lamina V1 cells of the primary somatosensory cortex in the rat: A single-cell labeling study
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Zhang Z-W, Deschênes M. Intracortical axonal projections of lamina V1 cells of the primary somatosensory cortex in the rat: a single-cell labeling study. J Neurosci. 17:1997;6365-6379.
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(1997)
J Neurosci
, vol.17
, pp. 6365-6379
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Zhang Z-W1
Deschênes, M.2
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9
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0031017794
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A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex
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In this immunohistochemical study, the authors report on two new monoclonal antibodies, Cat-315 and Cat-316, which, together with Cat-301, define a family of at least seven related but distinct chondroitin sulfate proteoglycans expressed on the extracellular surface of cell bodies and proximal dendrites. The three antibodies define nonidentical subsets of neurons in the cat visual cortex, and the authors conclude that different neuronal subpopulations express distinct complements of cell-surface antigens.
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Lander C, Kind P, Maleski M, Hockfield S. A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex. J Neurosci. 17:1997;1928-1939 In this immunohistochemical study, the authors report on two new monoclonal antibodies, Cat-315 and Cat-316, which, together with Cat-301, define a family of at least seven related but distinct chondroitin sulfate proteoglycans expressed on the extracellular surface of cell bodies and proximal dendrites. The three antibodies define nonidentical subsets of neurons in the cat visual cortex, and the authors conclude that different neuronal subpopulations express distinct complements of cell-surface antigens.
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(1997)
J Neurosci
, vol.17
, pp. 1928-1939
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Lander, C.1
Kind, P.2
Maleski, M.3
Hockfield, S.4
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10
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0031240016
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Callosally projecting neurons in the macaque monkey V1/V2 border are enriched in nonphosphorylated neurofilament protein
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of special interest
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of special interest Hof PR, Ungerleider LG, Adams MM, Webster MJ, Gattass R, Blumberg DM, Morrison JH. Callosally projecting neurons in the macaque monkey V1/V2 border are enriched in nonphosphorylated neurofilament protein. Vis Neurosci. 5:1997;981-988.
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(1997)
Vis Neurosci
, vol.5
, pp. 981-988
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Hof, P.R.1
Ungerleider, L.G.2
Adams, M.M.3
Webster, M.J.4
Gattass, R.5
Blumberg, D.M.6
Morrison, J.H.7
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11
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0023237719
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Connections between pyramidal neurons in layer 5 of cat visual cortex (area 17)
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Gabbott PLA, Martin KAC, Whitteridge D. Connections between pyramidal neurons in layer 5 of cat visual cortex (area 17). J Comp Neurol. 259:1987;364-381.
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(1987)
J Comp Neurol
, vol.259
, pp. 364-381
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Gabbott, P.L.A.1
Martin, K.A.C.2
Whitteridge, D.3
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12
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0027536049
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Synapses of extrinsic and intrinsic origin made by callosal projection neurons in mouse visual cortex
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Czeiger D, White EL. Synapses of extrinsic and intrinsic origin made by callosal projection neurons in mouse visual cortex. J Comp Neurol. 330:1993;502-513.
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(1993)
J Comp Neurol
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Czeiger, D.1
White, E.L.2
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14
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0031052266
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Calretinin-immunoreactive local circuit neurons in area 17 of the cynomolgus monkey, Macaca fascicularis
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of special interest. This paper demonstrates, using combined EM - immunocytochemistry, that the population of calretinin-positive interneurons in area 17 is polymorphic and has a dual laminar-specific projection pattern. In the superficial layers, most of the postsynaptic targets are other GABAergic neurons (81%). Collaterals also extend to the deeper layers (in area 17 but not area 18), and here synapses are formed mainly with spiny neurons, probably pyramidal cells (80%). The author concludes that calretinin-positive neurons act both to disinhibit supragranular neurons and to inhibit pyramidal output neurons in the deeper layers.
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Meskenaite V. Calretinin-immunoreactive local circuit neurons in area 17 of the cynomolgus monkey, Macaca fascicularis. of special interest J Comp Neurol. 379:1997;113-132 This paper demonstrates, using combined EM - immunocytochemistry, that the population of calretinin-positive interneurons in area 17 is polymorphic and has a dual laminar-specific projection pattern. In the superficial layers, most of the postsynaptic targets are other GABAergic neurons (81%). Collaterals also extend to the deeper layers (in area 17 but not area 18), and here synapses are formed mainly with spiny neurons, probably pyramidal cells (80%). The author concludes that calretinin-positive neurons act both to disinhibit supragranular neurons and to inhibit pyramidal output neurons in the deeper layers.
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(1997)
J Comp Neurol
, vol.379
, pp. 113-132
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Meskenaite, V.1
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15
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0030792365
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Massive autaptic self-innervation of GABAergic neurons in cat visual cortex
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of special interest. The authors determined the numbers and subcellular position of autapses on different smooth dendritic and spiny (pyramidal and nonpyramidal cell types, at the LM level, for 58 intracellularly filled neurons in cat visual cortex (areas 17 and 18). Subsequent EM analysis revealed that the degree of self-innervation (i.e. the number of autapses) is cell specific. Autapses were found to be abundant for GABAergic basket and dendrite-targeting interneurons (respectively, 12±7 and 22±12 - mean ±SD), but relatively sparse for double bouquet and pyramidal cells.
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Tamás G, Buhl EH, Somogyi P. Massive autaptic self-innervation of GABAergic neurons in cat visual cortex. of special interest J Neurosci. 17:1997;6352-6364 The authors determined the numbers and subcellular position of autapses on different smooth dendritic and spiny (pyramidal and nonpyramidal cell types, at the LM level, for 58 intracellularly filled neurons in cat visual cortex (areas 17 and 18). Subsequent EM analysis revealed that the degree of self-innervation (i.e. the number of autapses) is cell specific. Autapses were found to be abundant for GABAergic basket and dendrite-targeting interneurons (respectively, 12±7 and 22±12 - mean ±SD), but relatively sparse for double bouquet and pyramidal cells.
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(1997)
J Neurosci
, vol.17
, pp. 6352-6364
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Tamás, G.1
Buhl, E.H.2
Somogyi, P.3
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16
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1842333229
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Pathology and anatomy of synaptic connections between thick tufted pyramidal neurons in the developing rat neocortex
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of special interest. This and the following group of four papers [17, 18, 19, 20] report on technically demanding experiments that have elucidated principles of functional connectivity between pairs or triplets of identified neurons (in vitro). These studies have provided exquisitely precise data about the location, number, and efficacy of the synaptic contacts, and should permit further development and testing of predictions about network properties. In this study, the authors used dual-voltage recordings to demonstrate first-order reciprocal feedback, and then filled pre- and postsynaptic neurons in layer 5 of rat somatosensory cortex with biocytin and analyzed by correlated LM and EM. Among other results, the authors report a 20-fold range in efficacy of the synaptic contacts. The continuum in synaptic efficacy implies that layer 5 pyramidal neurons can be recruited to ensemble activity by as few as five strongly connected neighbors or by as many as 100 weakly
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Markram H, Lübke J, Frotscher M, Roth A, Sakmann B. Pathology and anatomy of synaptic connections between thick tufted pyramidal neurons in the developing rat neocortex. of special interest J Physiol. 500:1997;409-440 This and the following group of four papers [17, 18, 19, 20] report on technically demanding experiments that have elucidated principles of functional connectivity between pairs or triplets of identified neurons (in vitro). These studies have provided exquisitely precise data about the location, number, and efficacy of the synaptic contacts, and should permit further development and testing of predictions about network properties. In this study, the authors used dual-voltage recordings to demonstrate first-order reciprocal feedback, and then filled pre- and postsynaptic neurons in layer 5 of rat somatosensory cortex with biocytin and analyzed by correlated LM and EM. Among other results, the authors report a 20-fold range in efficacy of the synaptic contacts. The continuum in synaptic efficacy implies that layer 5 pyramidal neurons can be recruited to ensemble activity by as few as five strongly connected neighbors or by as many as 100 weakly connected pyramidal neighbors.
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(1997)
J Physiol
, vol.500
, pp. 409-440
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Markram, H.1
Lübke, J.2
Frotscher, M.3
Roth, A.4
Sakmann, B.5
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17
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0030928342
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Effect, number, and location of synapses made by single pyramidal cells onto aspiny interneurones of cat visual cortex
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of outstanding interest. of outstanding interest. Five synaptically coupled pyramidal-to-interneuron pairs in slices of cat visual cortex were physiologically characterized, labeled with biocytin, and analyzed by correlated LM and EM. Among other results, the authors report a lack of correlation for the interneurons between synapse efficacy and location (perhaps because of the electrotonic compactness of the interneurons), and a small degree of paired-pulse depression (this is in variance with the results reported in [19] and the authors discuss possible reasons for the discrepancy). Because of a rapid decay of EPSPs, the authors postulate a requirement for a high degree of temporal synchrony among the input population, and infer that the three classes of interneurons examined may be predisposed to act as coincidence detectors. See also annotation [16].
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of outstanding interest Buhl EH, Tamás G, Szilagyi T, Stricker C, Paulsen O, Somogyi P. Effect, number, and location of synapses made by single pyramidal cells onto aspiny interneurones of cat visual cortex. of outstanding interest J Physiol. 500:1997;689-713 Five synaptically coupled pyramidal-to-interneuron pairs in slices of cat visual cortex were physiologically characterized, labeled with biocytin, and analyzed by correlated LM and EM. Among other results, the authors report a lack of correlation for the interneurons between synapse efficacy and location (perhaps because of the electrotonic compactness of the interneurons), and a small degree of paired-pulse depression (this is in variance with the results reported in [19] and the authors discuss possible reasons for the discrepancy). Because of a rapid decay of EPSPs, the authors postulate a requirement for a high degree of temporal synchrony among the input population, and infer that the three classes of interneurons examined may be predisposed to act as coincidence detectors. See also annotation [16].
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(1997)
J Physiol
, vol.500
, pp. 689-713
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Buhl, E.H.1
Tamás, G.2
Szilagyi, T.3
Stricker, C.4
Paulsen, O.5
Somogyi, P.6
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18
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0030988211
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Fast IPSPs elicited via multiple synaptic release sites by different types of GABAergic neurons in the cat visual cortex
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of outstanding interest. This paper applies similar techniques to [17] to investigate interneuron-to-pyramidal cell interactions and further discusses network properties. Three classes GABAergic neurons are identified and shown to have distinctive synaptic domains on the surface of their target cells. All three types elicit fast IPSPs, with moderate variability of amplitude and few failures of transmission. See also annotation [16].
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Tamás G, Buhl EH, Somogyi P. Fast IPSPs elicited via multiple synaptic release sites by different types of GABAergic neurons in the cat visual cortex. of outstanding interest J Physiol. 500:1997;715-738 This paper applies similar techniques to [17] to investigate interneuron-to-pyramidal cell interactions and further discusses network properties. Three classes GABAergic neurons are identified and shown to have distinctive synaptic domains on the surface of their target cells. All three types elicit fast IPSPs, with moderate variability of amplitude and few failures of transmission. See also annotation [16].
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(1997)
J Physiol
, vol.500
, pp. 715-738
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Tamás, G.1
Buhl, E.H.2
Somogyi, P.3
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19
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0030811192
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Synaptic interactions in neocortical local circuits: Dual intracellular recordings in vitro
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of special interest. of special interest. The authors studied the properties of local synaptic connections in slices of rat neocortex using dual intracellular recordings, which they correlated with cell and synaptic morphology. Repetitive firing of any one input produces depression in pyramid - pyramid pairs, but facilitation in pyramid - interneuron pairs. Specific parameters for time-, frequency- and voltage-dependent properties are derived and network functional properties discussed. See also annotation [16].
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of special interest Thomson AM, Deuchars J. Synaptic interactions in neocortical local circuits: dual intracellular recordings in vitro. of special interest Cereb Cortex. 7:1997;510-522 The authors studied the properties of local synaptic connections in slices of rat neocortex using dual intracellular recordings, which they correlated with cell and synaptic morphology. Repetitive firing of any one input produces depression in pyramid - pyramid pairs, but facilitation in pyramid - interneuron pairs. Specific parameters for time-, frequency- and voltage-dependent properties are derived and network functional properties discussed. See also annotation [16].
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(1997)
Cereb Cortex
, vol.7
, pp. 510-522
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Thomson, A.M.1
Deuchars, J.2
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20
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0030839124
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A network of tufted layer 5 pyramidal neurons
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of outstanding interest. This is an experimentally based characterization of a recurrent network of layer 5 pyramidal neurons and an examination of how the dynamics of electrical activity might influence the functional coupling of neurons ('network configuration'). Evidence is presented that extensive, nonrandom interconnections occur among layer 5 pyramidal cells, and that these are in parallel from multiple points of the network. Activity-dependent synaptic modification, which enables the association of activity patterns, is discussed as an added dimension to network dynamics. See also annotation [16].
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Markram H. A network of tufted layer 5 pyramidal neurons. of outstanding interest Cereb Cortex. 7:1997;523-533 This is an experimentally based characterization of a recurrent network of layer 5 pyramidal neurons and an examination of how the dynamics of electrical activity might influence the functional coupling of neurons ('network configuration'). Evidence is presented that extensive, nonrandom interconnections occur among layer 5 pyramidal cells, and that these are in parallel from multiple points of the network. Activity-dependent synaptic modification, which enables the association of activity patterns, is discussed as an added dimension to network dynamics. See also annotation [16].
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(1997)
Cereb Cortex
, vol.7
, pp. 523-533
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Markram, H.1
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21
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0028846119
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Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons
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Cobb SR, Buhl EN, Halasy K, Paulsen O, Somogyi P. Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature. 378:1995;75-78.
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(1995)
Nature
, vol.378
, pp. 75-78
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Cobb, S.R.1
Buhl, E.N.2
Halasy, K.3
Paulsen, O.4
Somogyi, P.5
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22
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0028810185
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Hippocampal CA1 interneurons: An in vivo intracellular labeling study
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Sik A, Penttonen M, Ylinen A, Buzsaki G. Hippocampal CA1 interneurons: an in vivo intracellular labeling study. J Neurosci. 1995;6651-6665.
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(1995)
J Neurosci
, pp. 6651-6665
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Sik, A.1
Penttonen, M.2
Ylinen, A.3
Buzsaki, G.4
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23
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0020961911
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Termination of afferent axons in macaque striate cortex
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Blasdel GG, Lund JS. Termination of afferent axons in macaque striate cortex. J Neurosci. 3:1983;1389-1413.
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(1983)
J Neurosci
, vol.3
, pp. 1389-1413
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Blasdel, G.G.1
Lund, J.S.2
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24
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0030960908
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Map of the synapses onto layer 4 basket cells of the primary visual cortex of the cat
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of special interest. The authors used a 'template-matching' approach whereby the major sets of inputs to basket cells were sorted and distinguished by size (resolved by EM). Best-fit results show that about equal numbers of excitatory synapses are provided by layer 6 pyramidal cells (43%) and spiny stellates of layer 4 (44%), whereas thalamic afferents contribute fewer (only 13%). Symmetric synapses may originate from other layer 4 basket cells.
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Ahmed B, Anderson JC, Martin KAC, Nelson JC. Map of the synapses onto layer 4 basket cells of the primary visual cortex of the cat. of special interest J Comp Neurol. 380:1997;230-242 The authors used a 'template-matching' approach whereby the major sets of inputs to basket cells were sorted and distinguished by size (resolved by EM). Best-fit results show that about equal numbers of excitatory synapses are provided by layer 6 pyramidal cells (43%) and spiny stellates of layer 4 (44%), whereas thalamic afferents contribute fewer (only 13%). Symmetric synapses may originate from other layer 4 basket cells.
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(1997)
J Comp Neurol
, vol.380
, pp. 230-242
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Ahmed, B.1
Anderson, J.C.2
Martin, K.A.C.3
Nelson, J.C.4
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25
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0031906036
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Sharp, local synchrony among putative feed-forward inhibitory interneurons of rabbit somatosensory cortex
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of special interest. A subgroup of highly branched thalamocortical axons is postulated to contact monosynaptically a population of barrel-specific inhibitory neurons. Cross-correlation techniques were used to substantiate the existence of such a highly interconnected thalamocortical network by actually demonstrating the predicted patterns of intra- or cross-barrel sharp synchrony. This network of synchronous inhibition may be viewed as a 'complete transmission line', and may be especially effective in suppressing excitatory drive to target cells that is weak and asynchronous.
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Swadlow HA, Beloozerova IN, Sirota MG. Sharp, local synchrony among putative feed-forward inhibitory interneurons of rabbit somatosensory cortex. of special interest J Neurophysiol. 79:1998;567-582 A subgroup of highly branched thalamocortical axons is postulated to contact monosynaptically a population of barrel-specific inhibitory neurons. Cross-correlation techniques were used to substantiate the existence of such a highly interconnected thalamocortical network by actually demonstrating the predicted patterns of intra- or cross-barrel sharp synchrony. This network of synchronous inhibition may be viewed as a 'complete transmission line', and may be especially effective in suppressing excitatory drive to target cells that is weak and asynchronous.
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(1998)
J Neurophysiol
, vol.79
, pp. 567-582
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Swadlow, H.A.1
Beloozerova, I.N.2
Sirota, M.G.3
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26
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0031893278
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Temporal modulation of spatial borders in rat barrel cortex
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of special interest. Optical imaging was used to visualize the region of rat barrel cortex activated by deflection of a single whisker at different frequencies. Stimulation at higher frequencies was found to result in more focussed physiological responses. Given that spread of activation is modulated in a dynamic fashion by the frequency of vibrissa stimulation, the authors suggest a labile and complex functional mapping that extends beyond the CO-based anatomical maps of rat barrel cortex.
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Sheth BR, Moore CI, Sur M. Temporal modulation of spatial borders in rat barrel cortex. of special interest J Neurophysiol. 79:1998;464-470 Optical imaging was used to visualize the region of rat barrel cortex activated by deflection of a single whisker at different frequencies. Stimulation at higher frequencies was found to result in more focussed physiological responses. Given that spread of activation is modulated in a dynamic fashion by the frequency of vibrissa stimulation, the authors suggest a labile and complex functional mapping that extends beyond the CO-based anatomical maps of rat barrel cortex.
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(1998)
J Neurophysiol
, vol.79
, pp. 464-470
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Sheth, B.R.1
Moore, C.I.2
Sur, M.3
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27
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0030928570
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Differential regulation of neocortical synapses by neuromodulators and activity
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B receptors; only TC synapses were enhanced by nicotinic acetylcholine receptors; and both were suppressed by muscarinic acetylcholine receptors.
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B receptors; only TC synapses were enhanced by nicotinic acetylcholine receptors; and both were suppressed by muscarinic acetylcholine receptors.
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(1997)
Neuron
, vol.19
, pp. 679-686
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Gil, Z.1
Connors, B.W.2
Amitai, Y.3
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28
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0000716703
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Elements of cortical architecture: Hierarchy revisited
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K.S. Rockland, J.H. Kaas, Peters A. New York: Plenum
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Rockland KS. Elements of cortical architecture: hierarchy revisited. Rockland KS, Kaas JH, Peters A. Cerebral Cortex. Extrastriate Cortex in Primates. 12:1997;243-294 Plenum, New York.
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(1997)
Cerebral Cortex. Extrastriate Cortex in Primates
, vol.12
, pp. 243-294
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Rockland, K.S.1
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0030809644
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A polysynaptic feedback circuit in rat visual cortex
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Johnson RR, Burkhalter A. A polysynaptic feedback circuit in rat visual cortex. J Neurosci. 17:1997;7129-7140.
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(1997)
J Neurosci
, vol.17
, pp. 7129-7140
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Johnson, R.R.1
Burkhalter, A.2
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30
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0030947940
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Neural dynamics in a model of the thalamocortical system. I. Layers, loops and the emergence of fast synchronous rhythms
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Lumer ED, Edelman GM, Tononi G. Neural dynamics in a model of the thalamocortical system. I. Layers, loops and the emergence of fast synchronous rhythms. Cereb Cortex. 7:1997;207-227.
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(1997)
Cereb Cortex
, vol.7
, pp. 207-227
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Lumer, E.D.1
Edelman, G.M.2
Tononi, G.3
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31
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0031936312
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A mathematical approach to the connectivity between the cortical visual areas of the macaque monkey
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of special interest. The authors attempted to use topological interpolation in conjunction with factorial analysis and clustering techniques to go beyond static connectional networks. They caution, however, that factors such as the very high density of internal connections still need to be incorporated into this and other network models.
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Jouve B, Rosenstiehl P, Imbert M. A mathematical approach to the connectivity between the cortical visual areas of the macaque monkey. of special interest Cereb Cortex. 8:1998;28-39 The authors attempted to use topological interpolation in conjunction with factorial analysis and clustering techniques to go beyond static connectional networks. They caution, however, that factors such as the very high density of internal connections still need to be incorporated into this and other network models.
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(1998)
Cereb Cortex
, vol.8
, pp. 28-39
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Jouve, B.1
Rosenstiehl, P.2
Imbert, M.3
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33
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0030910394
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Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 in RNA and protein expression
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of outstanding interest. The authors used a double-labeling strategy to exploit the different time course of expression of zif268 mRNA (30 min) and zif268 protein (2h) to separately visualize neuronal populations that are activated by different conditions of visual exposure.
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Chaudhuri A, Nissanor J, Larocque S, Rioux L. Dual activity maps in primate visual cortex produced by different temporal patterns of zif268 in RNA and protein expression. of outstanding interest Proc Natl Acad Sci USA. 94:1997;2671-2675 The authors used a double-labeling strategy to exploit the different time course of expression of zif268 mRNA (30 min) and zif268 protein (2h) to separately visualize neuronal populations that are activated by different conditions of visual exposure.
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(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2671-2675
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Chaudhuri, A.1
Nissanor, J.2
Larocque, S.3
Rioux, L.4
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34
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Orderly geometric relationships, visualized by optical imaging, are reported between orientation and ocular dominance columns, and (somewhat more weakly) between orientation and spatial frequency domains. Low spatial frequency domains showed a tendency to avoid border regions of the ocular dominance columns. Thus, although rules can be defined, they are not rigidly followed as might be expected for a 'crystalline' organization. The authors suggest that the cortex is composed of 'mosaics' for different properties that are arranged in a nonrandom manner (see Figure 2).
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Hübener M, Shoham D, Grinvald A, Bonhoeffer T. Spatial relationships among three columnar systems in cat area 17. J Neurosci. 17:1997;9270-9284 Orderly geometric relationships, visualized by optical imaging, are reported between orientation and ocular dominance columns, and (somewhat more weakly) between orientation and spatial frequency domains. Low spatial frequency domains showed a tendency to avoid border regions of the ocular dominance columns. Thus, although rules can be defined, they are not rigidly followed as might be expected for a 'crystalline' organization. The authors suggest that the cortex is composed of 'mosaics' for different properties that are arranged in a nonrandom manner (see Figure 2).
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of special interest Wiser AK, Callaway EM. Ocular dominance columns and local projections of layer 6 pyramidal neurons in macaque primary visual cortex. Vis Neurosci. 14:1997;241-251.
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Combined optical imaging of orientation domains with extracellular injections of biocytin confirms that long-range intrinsic connections preferentially link neural domains of like orientation, and further demonstrates that the connections are anisotropic with respect to the topographic map of visual space. Less specificity may govern very local connections within 0.5 mm of the injection site.
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Bosking WH, Zhang Y, Schofield B, Fitzpatrick D. Orientation selectivity and the arrangement of horizontal connections in tree shrew striate cortex. J Neurosci. 17:1997;2112-2127 Combined optical imaging of orientation domains with extracellular injections of biocytin confirms that long-range intrinsic connections preferentially link neural domains of like orientation, and further demonstrates that the connections are anisotropic with respect to the topographic map of visual space. Less specificity may govern very local connections within 0.5 mm of the injection site.
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of outstanding interest. This paper presents a quantitative analysis of the anatomical pattern of lateral connectivity in cat visual cortex, as this is distinguished by excitatory and inhibitory subpopulations. By extrapolating from electrode recordings of single- and multi-unit activity, the authors mapped the anatomical pattern in relation to orientation domains. Using high-resolution bouton analysis, they confirmed that excitatory terminations have a preferential bias for iso-orientations, although they further report significant interpatch and cross-orientation labeling. Inhibitory connections, from basket cells, more commonly were between non-iso-orientation locations. There is a careful review of these results in the context of previous work, and a thoughtful discussion of how apparently low anatomical specificity might give rise to high functional specificity.
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of outstanding interest Kisvarday ZF, Toth E, Rausch M, Eysel UT. Orientation-specific relationship between populations of excitatory and inhibitory lateral connections in the visual cortex of the cat. Cereb Cortex. 7:1997;605-618 This paper presents a quantitative analysis of the anatomical pattern of lateral connectivity in cat visual cortex, as this is distinguished by excitatory and inhibitory subpopulations. By extrapolating from electrode recordings of single- and multi-unit activity, the authors mapped the anatomical pattern in relation to orientation domains. Using high-resolution bouton analysis, they confirmed that excitatory terminations have a preferential bias for iso-orientations, although they further report significant interpatch and cross-orientation labeling. Inhibitory connections, from basket cells, more commonly were between non-iso-orientation locations. There is a careful review of these results in the context of previous work, and a thoughtful discussion of how apparently low anatomical specificity might give rise to high functional specificity.
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of outstanding interest Malach R, Tootell RBH, Malonek D. Relationship between orientation domains, cytochrome oxidase stripes, and intrinsic horizontal connections in squirrel monkey area V2. Cereb Cortex. 4:1994;151-165.
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of outstanding interest. Optical imaging of orientation domains combined with tetrode recordings indicates that pinwheel centers (regions of reduced brightness in polar maps) are not characterized by a relative lack of neuronal orientation selectivity; rather, they represent the summation of cellular responses with greater variance in orientation preference.
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of outstanding interest. By combining optical recording of intrinsic signals with extracellular recording of receptive fields, the authors present evidence that the map of visual space shows strong and systematic local distortions in register with inhomogeneities in the orientation map. Correlated inhomogeneities in retinotopy and orientation may imply that cortical modules exhibit a wide range of functional relations and are differentially interconnected by local lateral processing.
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Das A, Gilbert CD. Distortions of visuotopic map match orientation singularities in primary visual cortex. of outstanding interest Nature. 387:1997;594-598 By combining optical recording of intrinsic signals with extracellular recording of receptive fields, the authors present evidence that the map of visual space shows strong and systematic local distortions in register with inhomogeneities in the orientation map. Correlated inhomogeneities in retinotopy and orientation may imply that cortical modules exhibit a wide range of functional relations and are differentially interconnected by local lateral processing.
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