Topical D-myo-inositol-1,2,6-trisphosphate and hexylbetaine treatment reduces albumin extravasation in experimental rat skin burn injury

Burns

Volumn 24, Issue 5, 1998, Pages 460-463

  Tarnow, Peter ^a   Jönsson, Anders ^a   Lindblom, Lucky ^a   Gustafsson, Torgny ^b   Cassuto, Jean ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b Research Park Idcon ^*  (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BETAINE DERIVATIVE; EVANS BLUE; INOSITOL 1,2,6 TRISPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; BURN; CONTROLLED STUDY; MALE; NONHUMAN; RAT; SKIN ABSORPTION; SPECTROPHOTOMETRY; TIME; TOPICAL DRUG ADMINISTRATION; WOUND DRESSING;

ADMINISTRATION, TOPICAL; ALBUMINS; ANALYSIS OF VARIANCE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BETAINE; BURNS; CONFIDENCE INTERVALS; DISEASE MODELS, ANIMAL; EVANS BLUE; INOSITOL PHOSPHATES; MALE; OCCLUSIVE DRESSINGS; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; SKIN; SPECTROPHOTOMETRY;

EID: 0032144005     PISSN: 03054179     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0305-4179(98)00044-8     Document Type: Article

References (28)

1. [1] Zimmerman TJ, Krizek TJ. Thermally induced dermal injury: a review of pathophysiologic events and therapeutic intervention. J Burn Care Rehabil 1984;5:193-201.
2. [2] Tarnow P, Jönsson A, Nellgård P, Cassuto J. Reduced albumin extravasation in experimental rat skin and muscle burn injury by D-myo-inositol-1,2,6-trisphosphate treatment. J Burn Care Rehabil 1996;17:207-212.
3. [3] Lund T, Reed RK. Alpha-trinositol inhibits edema generation and albumin extravasation in thermally injured skin. J Trauma 1994;36:761-765.
4. [4] Tarnow P, Jönsson A, Rimbäck G, Cassuto J. Increased dermal perfusion after skin burn injury by D-myo-inositol-1,2,6-trisphosphate. Burns 1996;22:363-368.
5. [5] Guy RH. Current status and future prospects of transdermal drug delivery. Pharm Res 1996;13:1765-1769.
6. [6] Blank IH. What are the functions of skin lost in burn injury that affect short- and long-term recovery? J Trauma 1984;24:S10-S12.
7. [7] Flynn GL, Behl CR, Linn E, Higuchi WI, Ho NFH, Pierson CL. Permeability of thermally damaged skin V: permeability over the course of maturation of a deep partial thickness wound. Burns Incl Therm Inj 1982;8:196-202.
8. [8] van Hoogdalem EJ, de Boer AG, Breimer DD. Intestinal drug absorption enhancement: an overview. Pharmacol Ther 1989;44:407-443.
9. [9] de la Maza A, Garcia PMT, Ribosa I, Sanchez Leal J. The alteration of small unilamellar liposomes by amphoteric alkylbetaine surfactants. Colloids and Surfaces 1991;61:281-290.
10. [10] Thompson RA, Allenmark S. Factors influencing the micellar catalyzed hydrolysis of long-chain alkyl betaines. J Colloid Interface Sci 1992;148:241-246.
11. [11] Cassuto J, Nellgård P, Stage L, Jönsson A. Amide local anesthetics reduce albumin extravasation in burn injuries. Anesthesiology 1990;72:302-307.
12. [12] Nazakawa H, Gustafsson TO, Traber LD, Herndon DN, Traber DL. α-trinositol decreases lung edema formation after smoke inhalation in an ovine model. J Appl Physiol 1994;76:278
13. [13] Gunther RA, Gustafsson T, Brofeldt BT. α-trinositol and decreased fluid balance following thermal injury. Circ Shock Suppl 1993;1:51.
14. [14] Iglesias G, Ziegler ST, Traber DL. PP56 decreases fluid retention following burn resuscitation in a porcine model. Proceedings ABA Annual Meeting, 1993: 94.
15. [15] Tarnow P, Cassuto J, Jönsson A, Nellgård P, Bennett A, Tavares IA. Effects of D-myo-inositol-1,2,6-trisphosphate on eicosanoid formation in burned skin. J Surg Res 1996;62:1-4.
16. [16] Youn Y.-K, La Londe C, Demling R. The role of mediators in the response to thermal injury. World J Surg 1992;16:30-36.
17. [17] Edvinsson L, Erlinge D, Sun XY, Hedner T. Neuropeptide Y in sympathetic co-transmission: recent advances in the search for neuropeptide Y antagonists. Pharmacol Toxicol 1994;74:193.
18. [18] Rodt SÅ, Reed RK, Ljungström M, Gustafsson T.O, Rubin K. The anti-inflammatory agent α-trinositol exerts its edema-preventing effect through modulation of β1-integrin function. Circ Res 1994;75:942-948.
19. [19] Yancey PH, Clark ME, Hand SC, Bowlus RD, Somero GN. Living with water stress: evolution of osmolyte systems. Science 1992;217:1214-1222.
20. [20] Burg MB, Kwon ED, Kültz D. Regulation of gene expression by hypertonicity. Ann Rev Physiol 1997;59:437-455.
21. [21] Garcia-Perez A, Burg MB. Importance of organic osmolytes for osmoregulation by renal medullary cells. Hypertension 1990;16: 595-602.
22. [22] Barak AJ, Beckenhauer HC, Tuma DJ. Betaine, ethanol, and the liver: a review. Alcohol 1996;13:395-398.
23. [23] Burg MB. Molecular bass of osmotic regulation. Am J Physiol 1995;268:F983-F996.
24. [24] Qureishi T, Nagarwalla N, Sarela A, Ahmed AR. Antibodies to the 70 kDa heat-shock protein in patients with thermal burns. Clin Immunol Immunopathol 1995;75:94-98.
25. [25] Lund PA. The roles of molecular chaperones in vivo. Essays in Biochem 1995;29:113-123.
26. [26] Sheikh-Hamad D, Garcia-Pérez A, Ferraris JD, Peters EM, Burg MB. Induction of gene expression by heat shock versus osmotic stress. Am J Physiol 1994;267:F28-F34.
27. [27] Petronini PG, De Angelis WM, Borghetti AF, Wheeler KP. Effect of betaine on HSP70 expression and cell survival during adaptation to osmotic stress. Biochem J 1993;293:553-558.
28. [28] Lund T, Onarheim H, Reed RK. Pathogenesis of edema formation in burn injuries. World J Surg 1992;16:2-9.