Zuclopenthixol, D1/D2 antagonist, for treatment of chronic aggressive schizophrenia and psychotic oligophrenic patients

European Psychiatry

Volumn 13, Issue 5, 1998, Pages 273-275

  Grinshpoon, A ^a   Moskowitz, M ^b   Valevski, A ^c   Kreizman, A ^b   Palei, L ^b   Mark, M ^a   Weizman, A ^c,d  

^a MEDICAL CORPS   (Israel)

^b Naveh Yaakov Psychiatric Hospital   (Israel)

^c GEHA MENTAL HEALTH CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Aggression; Dopamine D1 and D2 receptors; Mental retardation; Schizophrenia; Zuclopenthixol

Indexed keywords

DOPAMINE 1 RECEPTOR BLOCKING AGENT; DOPAMINE 2 RECEPTOR BLOCKING AGENT; ZUCLOPENTHIXOL ACETATE; ZUCLOPENTHIXOL DECANOATE;

ADULT; AGGRESSION; ANXIETY; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DRUG EFFICACY; FEMALE; HOSTILITY; HUMAN; INTRAMUSCULAR DRUG ADMINISTRATION; MALE; MENTAL DEFICIENCY; OLIGOPHRENIA; PRIORITY JOURNAL; PSYCHOSIS; RATING SCALE; SCHIZOPHRENIA; THOUGHT DISORDER; TREATMENT OUTCOME;

EID: 0032143160     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-9338(98)80035-7     Document Type: Article

References (10)

1. 2 antagonists. Pol J Pharmacol Pharm 1985 ; 36 : 249-64
2. 2 Cohen SA, Underwood MT. The use of clozapine in mental retarded and aggressive population. J Clin Psychiatry 1994 ; 55 : 440-4
3. 3 Karsten D, Vidimaeki T, Linna SL, Pollari L, Turunen S. Neuroleptic treatment of oligophrenic patients. Acta Psychiatrica Scand 1981 ; 64 : 39-45
4. 4 Kazi HAG. An open clinical trial with the long-acting neuroleptic zuclopenthixol decanoate in the maintenance treatment of schizophrenia. Pharmatherapeutica 1986 ; 4 : 555-60
5. 2 antagonist, versus haloperidol, a dopamine D2 antagonist, in tardive dyskinesia. Eur Neuropsychopharmacol 1991 ; 1 : 541-8
6. 6 Malt UF, Nystad R, Bache T, Noren O, Sjaastad M, Solberg KO et al. Effectiveness of zuclopenthixol compared with haloperidol in the treatment of behavioral disturbances in learning disabled patients. Br J Psychiatry 1995 ; 166 : 374-7
7. 7 Overall JE, Gorham DR. The Brief Psychiatric Rating Scale. Psychol Rep 1962 ; 10 : 799-812
8. 8 Ratey JJ, Leveroni C, Kilmer D, Gutheil C, Swartz B. The effects of clozapine on severely aggressive psychiatric inpatients in a state hospital. J Clin Psychiatry 1993 ; 54 : 219-23
9. 9 Walker CA. A double-blind comparative trial of the decanoates of clopenthixol and fluphenazine in the treatment of chronic schizophrenic outpatients. Pharmatherapeutica 1983 ; 3 : 289-93
10. 10 Wistedt B, Koskinen T, Thelander S, Nerdrum T, Pedersen V, Mølbjerg C. Zuclopenthixol decanoate and haloperidol decanoate in chronic schizophrenia: a double-blind multicenter study. Acta Psychiatr Scand 1991 ; 84 : 14-21