A Possible Involvement of Oxidative Lung Injury in Endotoxin-Induced Bronchial Hyperresponsiveness to Substance P in Guinea Pigs

Toxicology and Applied Pharmacology

Volumn 151, Issue 2, 1998, Pages 245-253

  Iwamae, Shigenori ^a   Tsukagoshi, Hideo ^a   Hisada, Takeshi ^a   Uno, Daisuke ^a   Mori, Masatomo ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Airway inflammation; Bronchial hyperresponsiveness; Endotoxin; Oxidative lung injury; Phosphodiesterase inhibitor

Indexed keywords

ANIMALIA; CAVIA; CAVIA PORCELLUS; SUS SCROFA;

ACETOPHENONE DERIVATIVE; AMINOPHYLLINE; APOCYNIN; DRUG DERIVATIVE; ENDOTOXIN; ENZYME INHIBITOR; HYPOCHLOROUS ACID; LIPID PEROXIDE; MEMBRANE METALLOENDOPEPTIDASE; NONSTEROID ANTIINFLAMMATORY AGENT; PAPAVERINE; PHOSPHODIESTERASE; PURINE DERIVATIVE; REACTIVE OXYGEN METABOLITE; SDZ ISQ 844; SDZ MKS 492; SUBSTANCE P;

ANIMAL; ARTICLE; BLOOD; BRONCHUS; BRONCHUS HYPERREACTIVITY; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; DRUG HYPERSENSITIVITY; ENZYMOLOGY; GUINEA PIG; LEUKOCYTE; LUNG; MALE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY;

ACETOPHENONES; AMINOPHYLLINE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRONCHI; BRONCHIAL HYPERREACTIVITY; DRUG HYPERSENSITIVITY; ENDOTOXINS; ENZYME INHIBITORS; GUINEA PIGS; HYPOCHLOROUS ACID; LEUKOCYTES; LIPID PEROXIDES; LUNG; MALE; NEPRILYSIN; OXIDATIVE STRESS; PAPAVERINE; PHOSPHORIC DIESTER HYDROLASES; PURINONES; REACTIVE OXYGEN SPECIES; SUBSTANCE P;

EID: 0032135671     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8476     Document Type: Article

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