Effect of Arbutin on Melanogenic Proteins in Human Melanocytes

Pigment Cell Research

Volumn 11, Issue 4, 1998, Pages 206-212

  Chakraborty, Ashok K ^a,b   Funasaka, Yoko ^a   Komoto, Mari ^a   Ichihashi, Masamitsu ^a  

^a KOBE UNIVERSITY   (Japan)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Arbutin; Dhica polymerase; Melanogenesis; TRP 1; TRP 2; Tyrosinase

Indexed keywords

5,6 DIHYDROXY 2 INDOLYLCARBOXYLIC ACID; 5,6-DIHYDROXY-2-INDOLYLCARBOXYLIC ACID; ARBUTIN; DOPACHROME ISOMERASE; INDOLE DERIVATIVE; ISOMERASE; MELANIN; MEMBRANE PROTEIN; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASE; POLYMER; PROTEIN; TYROSINASE RELATED PROTEIN; TYROSINASE-RELATED PROTEIN; TYRP1 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ARTICLE; BIOSYNTHESIS; CELL COUNT; CELL CULTURE; DRUG EFFECT; ENZYMOLOGY; HUMAN; IMMUNOLOGY; MALE; MELANOCYTE; METABOLISM; WESTERN BLOTTING;

ADOLESCENT; ADULT; ARBUTIN; BLOTTING, WESTERN; CELL COUNT; CELLS, CULTURED; HUMANS; INDOLES; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MELANINS; MELANOCYTES; MEMBRANE GLYCOPROTEINS; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; POLYMERS; PROTEINS;

EID: 0032135158     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0749.1998.tb00731.x     Document Type: Article

References (42)

1. Akiu S., Y. Suzuki, T. Asahara, Y. Fujinuma, and M. Fukuda (1991) Inhibitory effect of arbutin on melanogenesis - Biochemical study using cultured B16 melanoma cells - (in Japanese). Jpn. J. Dermatol., 101:609-613.
2. Arndt K.A. and T.B. Fitzpatrick (1965) Topical use of hydroquinone as a depigmenting agent. J. Am. Med. Assoc., 194:117-119.
3. Bolognia J.L., S.A. Sodi, and J.M. Pawelek (1991) Two separate pathways in the regulation of pigmentation. J. Invest. Dermatol., 96:632.
4. Bouchard B., V Del Marmol, I. Jackson, D. Cherif, and L. Dubertret (1994) Molecular characterization of a human tyrosinase related-protein-2 cDNA. Patterns of expression in melanocytic cells. Eur. J. Biochem., 219:127-134.
5. Chakraborty AK, Chakraborty A, and Chakraborty DP (1993) Hydroquinone simultaneously induces indole amine 2,3-dioxygenase (IOD) and inhibits tyrosinase in bufo melanostictus. Life Sci., 52:1695-1698.
6. Chakraborty A.K., J. Platt, K.K. Kim, B.S. Kwon, D.C. Bennett, and J.M. Pawelek (1996) Polymerization of 5,6-dihydroxyindole-2-carboxylic acid to melanin by the pmel17/silver locus protein. Eur. J. Biochem., 236:180-188.
7. Chen Y.M. and W. Chavin (1976) Hydroquinone activation and inhibition of tyrosinase. In: Pigment cell, V Riley, ed. Basel, Karger, Vol. 3, pp. 105-112.
8. Fuller B.B., I. Niekrasz, and G.E. Hoganson (1990) Down regulation of tyrosinase mRNA levels in melanoma cells by tumor promoters and by insulin. Mol. Cell. Endocrinol., 72:81-87.
9. Funasaka Y., T. Boulton, M. Cobb, Y. Yarden, B. Fan, S.D. Lyman, D.E. Williams, D.M. Anderson, R. Zakut, Y. Mishima, and R. Halaban (1992) c-kit-kinase induces a cascade of protein tyrosine phosphorylation in normal human melanocytes in response to mast cell growth factor and stimulates mitogen-activated protein kinase but is down-regulated in melanomas. Mol. Biol. Cell., 3:197-209.
10. Halaban R. and G.E. Moellmann (1990) Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity. Proc. Natl. Acad Sci. U.S.A., 87:4809-4813,
11. Hearing V.J., and K. Tsukamoto (1991) Enzymatic control of pigmentation in mammals. FASEB J., 5:2902-2909.
12. Hearing V.J. (1993) Unraveling the melanocytes. Am. J. Hum. Genet., 52:1-7.
13. Hearing V.J (1998) The regulation of melanin formation. In: The pigmentary system: Physiology and pathophysiology. Nordlund J.J., Boissy R.E., Hearing V.J., King R.A., Ortonne J.P., eds. Oxford Univ. Press, New York, pp. 423-438.
14. Hoganson G.E., F. Ledwitz-Rigby, R.L. Davidson, and B.B. Fuller (1989) Regulation of tyrosinase mRNA levels in mouse melanoma cell clones by melanocyte-stimulating hormone and cyclic AMP Somatic Cell Mol. Genet., 15:255-263.
15. Jackson I.J. (1988) A cDNA encoding tyrosinase-related protein maps to the brown locus in mice. Proc. Natl. Acad. Sci. U.S.A., 85:4392-4396.
16. Jackson I.J., D.M. Chambers, E.M. Rinchik, and D.C. Bennett (1990) Characterization of TRP-1 mRNA levels in dominant and recessive mutations at the mouse brown (b) locus. Genetics, 126:451-459.
17. Jimbow K., H. Obata, M.A. Pathak, and T.B. Fitzpatrick (1974) Mechanism of depigmentation by hydroquinone. J. Invest. Dermatol., 62:436-439.
18. Jimenez M., K. Tsukamoto, and V.J. Hearing (1991). Tyrosinases from two different loci are expressed by normal and by transformed melanocytes. J. Biol. Chem., 266:1147-1156.
19. Jimenez-Cervantes C., J.C. Garcia-Borron, P. Valverde, F. Solano, and J.A. Lozano (1993) Tyrosinase isoenzymes in mammalian melanocytes. I. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma. Eur J. Biochem., 217:549-556.
20. Jimenez-Cervantes C., F. Solano, T. Kobayashi, K. Urabe, V.J. Hearing, J.A. Lozano, and J.C. Garcia-Borron (1994) A new enzymatic function in the melanogenic pathway: The DHICA oxidase activity of tyrosinase related protein-1 (TRP-1). J Biol Chem 269:17993-18001.
21. Kobayashi T., K. Urabe, A.J. Winder, C. Jimenez-Cervantes, G. Imokawa, T. Brewington, F. Solano, J.C. Garcia-Borron, and V.J. Hearing (1994) Tyrosinase related protein 1 (TRP-1) functions as a DHICA oxidase in melanin biosynthesis. EMBO J., 13:5818-5825.
22. Korner A.M. and J.M. Pawelek (1980) DOPAchrome conversion: A possible control point in melanin biosynthesis. J. Invest. Dermatol., 75:192-195.
23. Maeda K. and M. Fukuda (1996) Arbutin: Mechanism of its depigmenting action in human melanocyte culture. J. Pharmaceutical Exp. Therapeut, 276:765-769.
24. Martinez-Esparza M., C. Jimenez-Cervantes, J.C. Garcia-Borron, J.A. Lozano, V Del Marmol, G. Ghanem, and F. Solano (1997) Comparison of TRPs from murine and human malignant melanocytes. Pigment. Cell Res., 10:229-235.
25. Naeyaert J.M., M. Eller, P.R. Gordon, H.Y. Park, and B.A. Gilchrest (1991) Pigment content of cultured human melanocytes does not correlate with tyrosinase message level. Br. J. Dermatol., 125:297-303.
26. Oka M., M. Ichihashi, and A.K. Chakraborty (1996) Enhanced expression of protein kinase C subspecies during stimulation of melanogenesis in B16 mouse melanoma cells. J. Invest. Dermatol., 106:377-378.
27. Orlow S.J., M.P. Osber, and J. Pawelek (1992) Synthesis and characterization of melanins from dihydroxyindole-2- carboxylic acid and dihydroxyindole. Pigment Cell Res., 5:113-121.
28. Orlow S.J., B.K. Zhou, A.K. Chakraborty, M. Drucker, S. Pifko-Hirst, and J.M. Pawelek (1994) High molecular weight forms of tyrosinase and the tyrosinase-related proteins: Evidence for a melanogenic complex. J Invest Dermatol 103:196-201.
29. Passi S. and M. Nazzaro-Porro (1981). Molecular basis of substrate and inhibitory specificity of tyrosinase. Br. J. Dermatol., 104:659-665.
30. Pawelek J. (1978) Melanoma cells in culture. Methods Enzymol., 58:564-570.
31. Pawelek J.M., A.K. Chakraborty, M.P. Osber, S.J. Orlow, K.K. Min, K.E. Rosenzweig, and J.L. Bolognia (1992) Molecular cascades in UV-induced melanogenesis: A central role for melanotropins. Pigment Cell Res., 5:348-356.
32. Penny K.B, C.J. Smith, and J.C. Allen (1984) Depigmenting action of hydroquinone depends on disruption of fundamental cell processes. J. Invest. Dermatol., 82:308-310.
33. Smith C.J., K.B. O'Hare, and J.C. Allen (1988) Selective cytotoxicity of hydroquinone for melanoma derived cells is mediated by tyrosinase activity but independent of melanin content. Pigment Cell Res., 1:386-389.
34. Sugai T (1992) Clinical effects of arbutin in patients with chloasma (in Japanese). Hifu (Skin Res.) 34:522-529.
35. Taylor M.W. and G. Feng (1991) Relationship between interferon-γ, indoleamine 2,3-dioxygenase and tryptophan catabolism (Reveiw). FASEB J., 5:2516-2522.
36. Tsukamoto K., I.J. Jackson, K. Urabe, P.M. Montague, and V.J. Hearing (1992) A second tyrosinase related protein, TRP-2 is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J., 11:519-526.
37. Vijayasaradhi S., B. Bouchard, and A.N. Houghton (1990) The melanoma antigen gp75 is the human homologue of the mouse b (brown) locus gene product. J. Exp. Med., 171:1375-1380.
38. Vijayasaradhi S., P.M. Doskoch, A.N. Houghton (1992) Biosynthesis and intracellular movement of the melanosomal membrane glycoprotein gp75, the human b (Brown) locus product. Exp. Cell Res., 196:233-240.
39. Winder A.J., A. Wittbjer, E. Rosengren, and H. Rorsman (1993) The mouse brown (b) locus protein has DOPAchrome tautomerase activity and is located in lysosomes in transfected fibroblasts. J. Cell Sci., 106:153-166.
40. Winder A.J., T. Kobayashi, K. Tsukamoto, K. Urabe, P. Aroca K. Kameyama, and V.J. Hearing (1994) The tyrosinase gene family: Interactions of melanogenic proteins to regulate melanogenesis. Cell. Mol. Biol. Res., 40:613-626.
41. Zhao H., Y. Zhao, J.J. Nordlund, and R.E. Boissy (1994) Human TRP-1 has tyrosine hydroxylase activity but no DOPA oxidase activity. Pigment Cell. Res., 7:131-140.
42. Zhao H., D.J. Eling, E.E. Medrano, and R.E. Boissy (1996) Retroviral infection with human tyrosinase-related protein-1 (TRP-1) cDNA upregulates tyrosinase activity and melanin synthesis in a TRP-1-deficient melanoma cell line. J. Invest. Dermatol., 106:744-752.