Decreased glucose response to insulin is maximal within 24 hours of somatotropin injection in growing pigs

Domestic Animal Endocrinology

Volumn 15, Issue 4, 1998, Pages 267-270

  Kerber, Jill A ^a   Wray Cahen, Diane ^a   Boyd, R Dean ^b   Bauman, Dale E ^a  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; INSULIN; RECOMBINANT PROTEIN;

ANIMAL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ARTICLE; BLOOD; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE CLAMP TECHNIQUE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; GROWTH, DEVELOPMENT AND AGING; INSULIN BLOOD LEVEL; INSULIN RESPONSE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIPOGENESIS; MALE; METABOLISM; NONHUMAN; SUBCUTANEOUS DRUG ADMINISTRATION; SWINE;

ANIMALS; BLOOD GLUCOSE; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TOLERANCE TEST; GROWTH HORMONE; INJECTIONS, SUBCUTANEOUS; INSULIN; MALE; RECOMBINANT PROTEINS; SWINE;

EID: 0032129122     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0739-7240(98)00012-5     Document Type: Article

References (10)

1. Wray-Cahen D., Boyd R.D., Bauman D.E., Ross D.A. Effect of porcine somatotropin on the response of growing pigs to acute challenges of glucose, insulin and epinephrine and during a hyperinsulinemic clamp. Domest Anim Endocrinol. 10:1993;103-115.
2. Wray-Cahen D. Metabolic effects of porcine somatotropin in the growing pig. Ph.D. dissertation. 1992;Cornell University, Ithaca, NY.
3. Dunshea FR, Harris DM, Bauman DE, Boyd RD, Bell AW. Effect of porcine somatotropin on in vivo glucose kinetics and lipogenesis in growing pigs. J Anim Sci 70:141-151, 1992.
4. Walton P.E., Etherton T.D., Chung C.S. Exogenous pituitary and recombinant growth hormones induce insulin and insulin-like growth factor 1 resistance in pig adipose tissue. Domest Anim Endocrinol. 4:1987;183-189.
5. Gopinath R., Etherton T.D. Effects of porcine growth hormone on glucose metabolism in pigs II. Glucose tolerance, peripheral tissue insulin sensitivity and glucose kinetics . J Anim Sci. 67:1989;689-697.
6. Gopinath R., Etherton T.D. Effects of porcine growth hormone on glucose metabolism in pigs I. Acute and chronic effects on plasma glucose and insulin status . J Anim Sci. 67:1989;682-688.
7. Caperna T.J., Steele N.C., Evock-Clover C.M., Brocht D., McMurtry J.P., Rosebrough R.W. Acute effects of administration of porcine growth hormone on circulating levels of hormones and metabolites in 20-, 40- and 60-kilogram gilts. J Anim Sci. 71:1993;897-905.
8. Dunshea FR, Bauman DE, Boyd RD, Bell AW. Temporal response of circulating metabolites and hormones during somatotropin treatment of growing pigs. J Anim Sci 70:123-131, l991.
9. Wray-Cahen D., Bell A.W., Boyd R.D., Ross D.A., Bauman D.E., Krick B.J., Harrell R.J. Effect of porcine somatotropin and insulin on nutrient uptake by the hindlimb of growing pigs. J Nutr. 125:1995;125-135.
10. Wray-Cahen D., Ross D.A., Bauman D.E., Boyd R.D. Metabolic effects of porcine somatotropin Nitrogen and energy balance and characterization of the temporal pattern of blood metabolites and hormones . J Anim Sci. 69:1991;1503-1524.