A novel non-polyglutamable anti-folate, MX-68, inhibits the induction of experimental autoimmune uveitis in rats

Experimental Eye Research

Volumn 67, Issue 1, 1998, Pages 1-8

  Hiraoka, Miki ^a   Mihara, Masahiko ^b   Takeda, Yasuhisa ^b   Miyasaka, Nobuyuki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Experimental autoimmune uveitis; Methotrexate; MX 68; Polyglutamation

Indexed keywords

COLLAGEN; COLLAGEN ANTIBODY; CONCANAVALIN A; FOLIC ACID ANTAGONIST; FREUND ADJUVANT; METHOTREXATE; N [[4 [(2,4 DIAMINO 6 PTERIDINYL)METHYL] 3,4 DIHYDRO 2H 1,4 BENZOTHIAZIN 7 YL]CARBONYL]HOMOGLUTAMIC ACID; POLYGLUTAMIC ACID; RETINA S ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; LYMPH NODE CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; UVEITIS;

EID: 0032128395     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0473     Document Type: Article

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