A specific T-cell subset with CD4+/CD38- markers derived from HIV-1 carriers induces apoptosis in healthy donor-derived T-lymphocytes

Virus Research

Volumn 56, Issue 1, 1998, Pages 115-122

  Kameoka, Masanori ^a,b   Auwanit, Wattana ^c   Suzuki, Satoko ^a   Horikoshi, Haruko ^a   Khlai Khlam, Nattapong ^c   Meguro, Takashi ^d   Yamada, Kaneo ^d   Tanaka, Yasuharu ^b   Yoshihara, Koichiro ^b   Luftig, Ronald B ^e   Ikuta, Kazuyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NARA MEDICAL UNIVERSITY   (Japan)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e LOUISIANA STATE UNIV MEDICAL CENTER   (United States)

Author keywords

AIDS; Apoptosis; Effector cells; HIV; T Lymphocytes

Indexed keywords

CD38 ANTIGEN; CD4 ANTIGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; APOPTOSIS; ARTICLE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; VIRUS PARTICLE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; HIV SERONEGATIVITY; HIV SEROPOSITIVITY; HIV-1; HUMANS; LYMPHOCYTE ACTIVATION; T-LYMPHOCYTE SUBSETS;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032128346     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1702(98)00052-5     Document Type: Article

References (28)

1. Ameisen J.C., Estaquier J., Idziorek T., de Bels F. The relevance of apoptosis to AIDS pathogenesis. Trends Cell Biol. 5:1995;27-32.
2. Ascher M.S., Sheppard H.W. AIDS as immune system activation. II. The panergic imnesia hypothesis. J. AIDS. 3:1990;177-191.
3. Auwanit W., Ayuthaya P.I.N., Nakaya T., Fujiwara S., Kurata T., Yamanishi K., Ikuta K. Unusually high seroprevalence of Borna disease virus in clade E human immunodeficiency virus type 1-infected patients with sexually transmitted diseases in Thailand. Clin. Diag. Lab. Immunol. 3:1996;590-593.
4. Bentwich Z., Kalinkovich A., Weisman Z. Immune activation is a dominant factor in the pathogenesis of African AIDS. Immunol. Today. 16:1995;187-191.
5. Briant L., Coudronnière N., Hebmann V.R., Benkirane M., Devaux C. Binding of HIV-1 virions or gp120-anti-gp120 immune complexes to HIV-1-infected quiescent peripheral blood mononuclear cells reveals latent infection. J. Immunol. 156:1996;3994-4004.
6. Estaquier J., Idziorek T., de Bels F., Barré-Sinoussi F., Hurtrel B., Aubertin A.-M., Venet A., Mehtali M., Muchmore E., Michel P., Mouton Y., Girard M., Ameisen J.C. Programmed cell death and AIDS: significance of T-cell apoptosis in pathogenic and nonpathogenic primate lentiviral infections. Proc. Natl. Acad. Sci. USA. 91:1994;9431-9435.
7. Fauci A.S. Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science. 262:1993;1011-1018.
8. Finkel T.H., Tudor-Williams G., Banda N.K., Cotton M.F., Curiel T., Monks C., Baba T.W., Ruprecht R.M., Kupfer A. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat. Med. 1:1995;129-134.
9. Gougeon M.-L., Garcia S., Heeney J., Tschopp R., Lecoeur H., Guetard D., Rame V., Dauguet C., Montagnier L. Programmed cell death in AIDS-related HIV and SIV infections. AIDS Res. Hum. Retrov. 9:1993;553-563.
10. Gougeon M.-L., Lecoeur H., Dulioust A., Enouf M.-G., Crouvoisier M., Goujard C., Debord T., Montagnier L. Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression. J. Immunol. 156:1996;3509-3520.
11. + T cells from human immunodeficiency virus-infected asymptomatic individuals. J. Exp. Med. 175:1992;331-340.
12. Gummuluru S., Novembre F.J., Lewis M., Gelbard H.A., Dewhurst S. Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14. Virology. 225:1996;21-32.
13. Ho D.D., Neumann A.U., Perelson A.S., Chen W., Leonard J.M., Markowitz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infections. Nature. 373:1995;123-126.
14. Ikuta K., Kameoka M., Luftig R.B. AIDS pathogenesis: the role of accessory gene mutations, leading to formation of long-lived persistently infected cells and/or apoptosis-inducing HIV-1 particles. Virus Res. 52:1997;145-156.
15. Kameoka M., Kimura T., Zheng Y.-H., Suzuki S., Fujinaga K., Luftig R.F., Ikuta K. Protease-defective, gp120-containing human immunodeficiency virus type 1 particles induce apoptosis more efficiently than does wild-type virus or recombinant gp120 protein in healthy donor-derived peripheral blood T cells. J. Clin. Microbiol. 35:1997;41-47.
16. + killer cells in a small subset, leading to induction of apoptosis in bystander cells. Int. Immunol. 9:1997;1453-1462.
17. Katsikis P.D., Wunderlich E.S., Smith C.A., Herzenberg L.A., Herzenberg L.A. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J. Exp. Med. 181:1995;2029-2036.
18. Katsikis P.D., García-Ojeda M.E., Wunderlich E.S., Smith C.A., Yagita H., Okumura K., Kayagaki N., Alderson M., Herzenberg L.A., Herzenberg L.A. Activation-induced peripheral blood T cell apoptosis is Fas independent in HIV-infected individuals. Int. Immunol. 8:1996;1311-1317.
19. + T cells from HIV-infected persons. J. Immunol. 153:1994;412-420.
20. Maldarelli F., Sato H., Berthold E., Orenstein J., Martin M.A. Rapid induction of apoptosis by cell-to-cell transmission of human immunodeficiency virus type 1. J. Virol. 69:1995;6457-6465.
21. + lymphocytes: a two-step model. Med. Hypotheses. 42:1994;159-168.
22. Meyaard L., Otto S.A., Jonker R.R., Mijinster M.J., Keet R.P.M., Miedema F. Programmed death of T cells in HIV-1 infection. Science. 257:1992;217-219.
23. Muro-Cacho C.A., Pantaleo G., Fauci A.S. Analysis of apoptosis in lymph nodes of HIV-infected persons. Intensity of apoptosis correlates with the general state of activation of the lymphoid tissue and not with stage of disease or viral burden. J. Immunol. 154:1995;5555-5566.
24. + blood lymphocytes are rapidly killed in vitro by contact with autologous human immunodeficiency virus-infected cells. Proc. Natl. Acad. Sci. USA. 92:1995;7312-7316.
25. + T cells apoptosis: a possible mechanism of bystander cell death in HIV infection. J. Immunol. 158:1997;2456-2463.
26. Wei X., Ghosh S.K., Taylor M.E., Johnson V.A., Emini E.A., Deutsch P., Lifson J.D., Bonhoeffer S., Nowak M.A., Hahn H.H., Saag M.S., Shaw G.M. Viral dynamics in human immunodeficiency virus type 1 infection. Nature. 373:1995;117-122.
27. Westendrop M.O., Frank R., Ochsenbauer C., Stricker K., Dhein J., Walczak H., Debatin K.-M., Krammer P.H. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 tat and gp120. Nature. 375:1995;497-500.
28. Westermann C.D., Hurtubise P.E., Linneman C.C., Swerdlow S.H. Comparison of histologic nodal reactive patterns, cell suspension immunophenotypic data, and HIV status. Mod. Pathol. 3:1990;54-60.