Effect of betaxolol, timolol and nimodipine on human and pig retinal arterioles

Experimental Eye Research

Volumn 67, Issue 1, 1998, Pages 73-81

  Yu, Dao Yi ^a   Su, Er Ning ^a   Cringle, Stephen J ^a   Alder, Valerie A ^a   Yu, Paula K ^a   Desantis, Louis ^b  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b ALCON RESEARCH LTD   (United States)

Author keywords

Betaxolol; Human; Nimodipine; Pig; Retinal arteriole; Timolol

Indexed keywords

ACETYLCHOLINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; CALCIUM CHANNEL BLOCKING AGENT; ENDOTHELIN 1; NIMODIPINE; NORADRENALIN; TIMOLOL;

ADULT; AGED; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY PERFUSION; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; CRYOPRESERVATION; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; HUMAN TISSUE; INTRAOCULAR PRESSURE; ISOLATED ARTERY; NONHUMAN; PRIORITY JOURNAL; RETINA ARTERY; SWINE; VASODILATATION;

EID: 0032128081     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1998.0495     Document Type: Article

References (34)

1. Alborch E., Salom J. B., Torregrosa G. Calcium channels in cerebral arteries. Pharmac. Ther. 68 (1):1995;1-34.
2. Bank H. L., Brockbank K. G. M. Basic principles of cryobiology. J. Cardiac. Surg. 2 (Suppl.):1987;137-143.
3. Beresford R., Heel R. C. Betaxolol, a review of it's pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension. Drugs. 31:1986;6-28.
4. Bessho H., Suzuki J., Narimatsu A., Tobe A. Antihypertensive effect of betaxolol a cardioselective β-adrenoceptor antagonist in experimental hypertensive rats. Nippon Yakurigaku Zasshi. 95:1990;347-354.
5. Brooks A. M. V., Gillies W. E. Ocular beta-blockers in glaucoma management: clinical pharmacological aspects. Drugs Aging. 2:1992;208-221.
6. Brubaker R. F. Flow of aqueous humor in humans (the Friedenwald lecture). Invest. Ophthalmol. Vis. Sci. 32 (13):1991;3145-3165.
7. Chiou G. C. Y., Chen Y. J. Effects of antiglaucoma drugs on ocular blood flow in ocular hypertensive rabbits. J. Ocular Pharmacol. 9:1993;13-24.
8. Collignon-Brach J. Primary open-angle glaucoma and beta-blocking agents. International symposium on glaucoma, ocular flow, and drug treatment. 1992;Williams & Williams. p. 136-51.
9. Desantis L, Dahlin D., Barnes G. A role for the calcium channel blocking like action of betaxolol for providing therapeutic benefit to patients. Drance S. M. Update to glaucoma, ocular blood flow and drug treatment. 1995;137-143 Kugler Publications.
10. Ellis P., Muller-Schweinitzer E. Maintenance of functional activity of human pulmonary arteries after cryopreservation. Br. J. Pharmacol. 103 (2):1991;1377-1380.
11. Flammer J. To what extent are vascular factors involved in the pathogenesis of glaucoma? Kaiser H. J., Flammer J., Hendrickson P. Ocular blood flow. 1996;12-39 Karger.
12. Frishman W. H., Fuksbrumer M. S., Tannenbaum M. Topical ophthalmic beta-adrenergic blockade for the treatment of glaucoma and ocular hypertension. J. Clin. Pharmacol. 34:1994;795-803.
13. Grunwald J. E. Effect of topical timolol on the human retinal circulation. Invest. Ophthalmol. Vis. Sci. 27:1986;1713-1719.
14. Hester R. K., Chen Z., Becker E. J., McLaughlin M., Desantis L. The direct vascular relaxing action of betaxolol, carteolol and timolol in porcine long posterior ciliary artery. Surv. Ophthalmol. 38:1994;s125-34.
15. Hoste A. M., Sys S. U. The relaxant action of betaxolol on isolated bovine retinal microarteries. Curr. Eye Res. 13:1994;483-487.
16. Hoste A. M., Boels P. J., Andries L. J., Brutsaert D. L., de Laey J. J. Effects of beta-antagonists on contraction of bovine retinal microarteries in vitro. Invest. Ophthalmol. Vis. Sci. 31 (7):1990;1231-1237.
17. Ku D., Liu Q., Norton P., Caulfield J. Cryopreservation of coronary endothelium and endothelial-mediated responses. Cryobiology. 31:1994;82-89.
18. Liu S., Araujo S. V., Spaeth G. L., Katz L. L., Smith M. Lack of effect of calcium channel blockers on open angle glaucoma. J. Glaucoma. 5:1996;187-190.
19. Messmer C., Flammer J., Stumpfig D. Influence of betaxolol and timolol on the visual fields of patients with glaucoma. Am. J. Ophthalmol. 112 (5):1991;678-681.
20. Muller-Schweinitzer E. Cryopreservation: a useful technique for storing tissues for pharmacological investigations. Trends Pharmacol. Sci. 9:1988;221-223.
21. Netland P. A., Feke G. T., Lonno S., Goger D. G., Fujio N. Optic nerve head circulation after topical calcium channel blocker. J. Glaucoma. 5:1996;200-206.
22. Neufeld A. H., Bartels S. P. Receptor mechanisms for epinephrine and timolol. Lutjen-Drecoll E. Basic aspects of glaucoma research. 1982;113-122 Schattauer.
23. Nielsen P. J., Nyborg N. C. B. Adrenergic responses in isolated bovine retinal resistance arteries. Int. Ophthalmol. 13:1989;103-107.
24. Randall M. D. Vascular activities of the endothelins [Review] [148 refs.]. Pharmacology Therapeutics. 50 (1):1991;73-93.
25. Schoeffter P., Muller-Schweinitzer E. The preservation of functional activity of smooth muscle and endothelium in pig coronary arteries after storage at -190°C. J. Pharmacol. 42:1990;646-651.
26. Su E. N., Yu D. Y., Alder V. A., Yu P. K., Cringle S. J. Altered vasoactivity in the early diabetic eye: measured in the isolated perfused rat eye. Exp. Eye Res. 61:1995;699-712.
27. Sugiyama T., Moriya S., Oku H., Azuma I. Association of endothelin-1 with normal tension glaucoma: clinical and fundamental studies. Survey of Ophthalmology. 39:1995;Suppl. 1, S49-56.
28. Vuori M. L., Ali-Melkkila T., Kaila T., Iisalo E., Saari K. M. Plasma and aqueous humour concentrations and systemic effects of topical betaxolol and timolol in man. Acta Ophthalmol. 71:1993a;201-206.
29. Vuori M. L., Kaila T., Iisalo E., Saari K. M. Concentrations and antagonist activity of topically applied betaxolol in aqueous humour. Acta Ophthalmol. 71:1993b;677-681.
30. Yan H. Y., Chiou G. C. Y. Effects ofL-D. Ophthalmic Res. 19:1987;45-48.
31. Yu D. Y., Alder V. A., Su E. N., Mele E. M., Cringle S. J., Morgan W. H. Agonist response of human isolated posterior ciliary artery. Invest. Ophthalmol. Vis. Sci. 33 (1):1992a;48-54.
32. Yu D. Y., Su E. N., Alder V. A., Cringle S. J., Mele E. M. Pharmacological and mechanical heterogeneity of cat isolated ophthalmociliary artery. Exp. Eye Res. 54:1992b;347-359.
33. Yu D. Y., Alder V. A., Cringle S. J., Su E. N., Yu P. K. Vasoactivity of intraluminal and extraluminal agonists in perfused retinal arteries. Invest. Ophthalmol. Vis. Sci. 35:1994;4087-4099.
34. 2+. Drance S. Vascular risk factors and neuroprotection in glaucoma - update 1996. 1997;123-134 Kugler Publications.