Stage-specific substrate phosphorylation by a Ca2+/calmodulin-dependent protein kinase in Trypanosoma cruzi

Journal of Eukaryotic Microbiology

Volumn 45, Issue 4, 1998, Pages 392-396

  Ogueta, Sandra B ^b   Macintosh, Gustavo C ^c   Téllez Iñon, Maria T ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b JULES STEIN EYE INSTITUTE   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Amastigotes; Differentiation; Epimastigotes; Trypanosomatids; Trypomastigotes

Indexed keywords

CALCIUM; CALMODULIN; DEVELOPMENTAL CYCLE; ENZYME ACTIVATION; IDENTIFICATION; MORPHOGENESIS; PHOSPHORYLATION; POLYCLONAL ANTIBODY; PROTEIN KINASE; WESTERN BLOTTING;

TRYPANOSOMA CRUZI;

EID: 0032127976     PISSN: 10665234     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1550-7408.1998.tb05089.x     Document Type: Article

References (34)

1. Aboagye-Kwarteng, T., Ole-Moiyoi, O. & D. Lonsdale-Eccles, J. 1991. Phosphorylation differences among proteins of bloodstream developmental stages of Trypanosoma brucei. Biochem. J., 275:7-14.
2. Andrews, N. W. & Colli, W 1982. Adhesion and interiorization of Trypanosoma cruzi in mammalian cells. J. Protozool., 29:264-269.
3. Casnellie, J. E. 1991. Assay of protein kinases using peptides with basic residues for phosphocellulose binding. Meth. Enzymol., 200:115-120.
4. Cazzulo, J. J., Franke de Cazzulo, B. M., Engel, J. C. & Cannata, J. J. B. 1985. End products and enzyme levels of aerobic glucose fermentation in trypanosomatids. Mol. Biochem. Parasitol., 16:329-343.
5. Cohen, P., Holmes, C. F. B. & Tsukitani, Y. 1990. Okadaic acid: a new probe for the study of cellular regulation. Trends Biochemi. Sci., 15:98-102.
6. Dell, K. R. & Engel, J. N. 1994. Stage-specific regulation of protein phosphorylation in Leishmania major. Mol. Biochem. Parasitol., 64:283-292.
7. 2+/calmodulin-dependent protein kinase. Neurochem. Res., 22:1151-1157.
8. Erondu, N. E. & Donelson, J. E. 1991. Characterization of trypanosome protein phosphatase 1 and 2A catalytic subunits. Mol. Biochem. Parasitol., 49:303-314.
9. 2+/calmodulin-dependent protein kinase II and its endogenous substrates in the induction of long-term potentiation. J. Biol. Chem., 270:6119-6124.
10. Gómez, M. L., Erijman, L., Arauzo, S., Torres, H. N. & Téllez-Iñó, M. T. 1989. Protein kinase C in Trypanosoma cruzi epimastigote forms: partial purification and characterization. Mol. Biochem. Parasitol., 36:101-108.
11. Hashimoto, Y. & Soderling, T. R. 1987. Calcium/calmodulin-dependent protein kinase II and calcium phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Arch. Biochem. Biophys., 252:418-425.
12. Hide, G., Graham, T., Buchanan, N., Tait, A. & Keith, K 1994. Trypanosoma brucei: characterization of protein kinases that are capable of autophosphorylation in vitro. Parasitology, 108:161-166.
13. Kelly, P. T. & Shenolikar, S. 1987. Role of autophosphorylation in regulating calmodulin-dependent protein kinases. Meth. Enzymol., 139:690-714.
14. 2+/calmodulin-dependent protein kinase II. Proc. Natl. Acad. Sci. USA, 83:4253-4257.
15. Lammel, E. M., Barbieri, M. A., Wilkowsky, S. E., Bertini, F. & Isola, E. L. 1996. Trypanosoma cruzi: involvement of intracellular calcium in multiplication and differentiation. Exp. Parasitol., 83:240-249.
16. Lisman, J. 1994. The CaM kinase II hypothesis for the storage of synaptic memory.Trends Neurosci., 17:406-412.
17. 2+/calmodulin-dependent protein kinase II by inter-and intrasubunit-catalyzed autophosphorylations. J. Biol. Chem., 269:13744-13747.
18. 2+/calmodulin-dependent protein kinase: expression in multiple human tissues. J. Biol. Chem., 258:5471-5479.
19. 2+/calmodulin-dependent protein kinase. FEBS Letters, 337:293-297.
20. 2+/calmodulin-dependent protein kinase from Trypanosoma cruzi. Mol. Biochem. Parasitol., 78:171-183.
21. Orr, G. .A., Tanowitz, H. B. & Wittner, M. 1992. Trypanosoma cruzi: stage expression of calmodulin-binding proteins. Exp. Parasitol., 74:127-133.
22. Parsons, M., Carter, V., Muthiani, A. & Murphy, N. 1995. Trypanosoma congolense: developmental regulation of protein kinases and tyrosine phosphorylation during the life cycle. Exp. Parasitol., 80: 507-514.
23. Parsons, M., Ledbetter, J. A., Schieven, G. L., Nel, A. E. & Kanner, S. B. 1994. Developmental regulation of pp44/46, tyrosine-phosphorylated proteins associated with tyrosine/serine kinase activity in Trypanosoma brucei. Mol. Biochem. Parasitol., 63:69-78.
24. Parsons, M., Valentine, M., Deans, J., Schieven, G. L. & Ledbetter, J. A. 1990. Distinct patterns of tyrosine phosphorylation during the life cycle of Trypanosoma brucei. Mol. Biochem. Parasitol., 45: 241-248.
25. 2+/calmodulin is inhibited by autophosphorylation of threonine within the calmodulin-binding domain. J. Biol. Chem., 265:11204-11212.
26. Rostas, J. A. P. & Dunkley, P. R. 1992. Distribution of multiple forms of calcium/calmodulin stimulated protein kinase II in brain. J. Neurochem., 59:1191-1202.
27. Ruben, L., Haghighat, N. & Campbell, A. 1990. Cyclical differentiation of Trypanosoma brucei involves changes in the cellular complement of calmodulin-binding proteins. Exp. Parasitol., 70:144-153.
28. 2+/calmodulin-dependent protein kinases. Curr. Op. Cell Biol., 5:247-253.
29. 2+/calmodulin-dependent protein kinase II by an autophosphorylation mechanism. J. Biol. Chem., 261:8581-8584.
30. 2+ during differentiation of bloodstream stages in vitro. Exp. Parasitol., 83:134-146.
31. Strack, S., Choi, S., Lovinger, D. M. & Colbran, R. J. 1997. Translocation of autophosphorylated calcium/calmodulin-dependent protein kinase II to the postsynaptic density. J. Biol.Chem., 272:13467-13470.
32. 2+-dependent cyclic AMP phosphodiesterase activity in Trypanosoma cruzi. Mol. Biochem. Parasitol., 17:143-153.
33. 2+/calmodulin-dependent protein kinase II. J. Biol. Chem., 265:4315-4320.
34. 2+/calmodulin-independent protein kinase II. Neuroreport, 7:637-641.