Cell proliferation in normal and atherosclerotic human aorta: Proliferative splash in lipid-rich lesions

Atherosclerosis

Volumn 139, Issue 1, 1998, Pages 41-48

  Orekhov, Alexander N ^a   R Andreeva, Elena ^a   Mikhailova, Irina A ^a   Gordon, David ^b  

^a INSTITUTE OF EXPERIMENTAL CARDIOLOGY   (Russian Federation)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Atherosclerosis; Human aorta; Immunocytochemistry; Inflammatory cells; Proliferation; Resident cells

Indexed keywords

CYCLINE; MONOCLONAL ANTIBODY;

ADULT; AORTA ATHEROSCLEROSIS; AORTA DISEASE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL PROLIFERATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INFLAMMATORY CELL; MALE; PRIORITY JOURNAL;

ADULT; ANTIBODIES, MONOCLONAL; AORTA; ARTERIOSCLEROSIS; CELL COUNT; CELL DIVISION; HUMANS; IMMUNOHISTOCHEMISTRY; LIPIDS; MIDDLE AGED; PROLIFERATING CELL NUCLEAR ANTIGEN; TUNICA INTIMA;

EID: 0032127792     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(98)00044-6     Document Type: Article

References (20)

1. Gordon D., Reidy M.A., Benditt E.P., Schwartz S.M. Cell proliferation in human coronary arteries. Proc Natl Acad Sci USA. 87:1990;4600-4604.
2. O'Brien E.R., Alpers C.E., Stewart D.K., Ferguson M., Tran N., Gordon D., Benditt E.P., Hinohara T., Simpson J.B., Schwartz S.M. Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy. Circ Res. 73:1993;223-231.
3. Katsuda S., Coltrera M.D., Ross R., Gown A.M. Human atherosclerosis. IV. Immunocytochemical analysis of cell activation and proliferation in lesions of young adults. Am J Pathol. 142:1993;1787-1793.
4. Pickering J.G., Weir L., Jekanowski J., Kearney M.A., Isner J.M. Proliferative activity in peripheral and coronary atherosclerotic plaque among patients undergoing percutaneous revascularization. J Clin Invest. 91:1993;1469-1480.
5. Rekhter M.D., Gordon D. Cell proliferation and collagen synthesis are two independent events in human atherosclerotic plaques. J Vasc Res. 31:1994;280-286.
6. Rekhter M.D., Gordon D. Does platelet-derived growth factor - A chain stimulate proliferation of arterial mesenchymal cells in human atherosclerotic plaques? Circ Res. 75:1994;410-417.
7. Rekhter M.D., Gordon D. Active proliferation of different cell types, including lymphocytes, in human atherosclerotic plaques. Am J Pathol. 147:1995;668-677.
8. Stary H.C., Chandler A.B., Glagov S., Guyton J.R., Insull W. Jr., Rosenfeld M.E., Schaffer S.A., Schwartz C.J., Wagner W.D., Wissler R.W. A definition of initial, fatty streak, and intermediate lesions of atherosclerosis: A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis. Am Heart Assoc Circ. 89:1994;2462-2478.
9. Stary H.C., Chandler A.B., Dinsmore R.E., Fuster V., Glagov S., Insull W. Jr., Rosenfeld M.E., Schwartz C.J., Wagner W.D., Wissler R.W. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis - A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis. Am Heart Assoc Arterioscler Thromb Vasc Biol. 15:1995;1512-1531.
10. Andreeva E.R., Pugach I.M., Orekhov A.N. Subendothelial smooth muscle cells of human aorta express macrophage antigen in situ and in vitro. Atherosclerosis. 135:1997;19-27.
11. Orekhov A.N., Andreeva E.R., Tertov V.V., Krushinsky A.V. Dissociated cells from different layers of adult human aortic wall. Acta Anat Basel. 119:1984;99-105.
12. Orekhov A.N., Karpova I.I., Tertov V.V., Rudchenko S.A., Andreeva E.R., Krushinsky A.V., Smirnov V.N. Cellular composition of atherosclerotic and uninvolved human aortic subendothelial intima. Light-microscopic study of dissociated aortic cells. Am J Pathol. 115:1984;17-24.
13. Rekhter M., Nicholls S., Ferguson M., Gordon D. Cell proliferation in human arteriovenous fistulas used for hemodialysis. Arterioscler Thromb. 13:1993;609-617.
14. Orekhov A.N., Kosykh V.A., Repin V.S., Smirnov V.N. Cell proliferation in normal and atherosclerotic human aorta. II. Autoradiographic observation on deoxyribonucleic acid synthesis in primary cell culture. Lab Invest. 48:1983;749-754.
15. Orekhov A.N., Tertov V.V., Kudryashov S.A., Khashimov Kh.A., Smirnov V.N. Primary culture of human aortic intima cells as a model for testing antiatherosclerotic drugs. Effects of cyclic AMP, prostaglandins, calcium antagonists, antioxidants, and lipid-lowering agents. Atherosclerosis. 60:1986;101-110.
16. Tertov V.V., Orekhov A.N., Ryong L.H., Smirnov V.N. Intracellular cholesterol accumulation is accompanied by enhanced proliferative activity of human aortic intimal cells. Tissue Cell. 20:1988;849-854.
17. Orekhov A.N., Tertov V.V., Kudryashov S.A., Smirnov V.N. Triggerlike stimulation of cholesterol accumulation and DNA and extracellular matrix synthesis induced by atherogenic serum or low density lipoprotein in cultured cells. Circ Res. 66:1990;311-320.
18. Tertov V.V., Orekhov A.N., Kudryashov S.A., Klibanov A.L., Ivanov N.N., Torchilin V.P., Smirnov V.N. Cyclic nucleotides and atherosclerosis: studies in primary culture of human aortic cells. Exp Mol Pathol. 47:1987;377-389.
19. Hajjar D.P., Weksler B.B., Falcone D.J., Hefton J.M., Tack-Goldman K., Minick C.R. Prostacyclin modulates cholesteryl ester hydrolitic activity by its effect on cyclic adenisine monophosphate in rabbit aorta smooth muscle cells. J Clin Invest. 70:1982;479-488.
20. Stout R.W., Cyclic A.M.P. A potent inhibitor of DNA synthesis in cultured endothelial and smooth muscle cells. Diabetologia. 22:1982;51-55.