ICV administration of CRF blocker (CRF(9-41 δ) helical) reduces morphine withdrawal in rats

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 22, Issue 5, 1998, Pages 775-785

  Brugger, Sara ^a   Sanchez, Rosa ^b   Brugger, Arturo J ^a   Martinez, Jose Antonio ^a,c  

^a UNIVERSITY OF MURCIA   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE ALBACETE   (Spain)

^c Unit of Pharmacology   (Spain)

Author keywords

CRF(9 41 ) helical antagonist; Hypothalamo pituitary adrenal axis; Morphine withdrawal syndrome; Opoid

Indexed keywords

CORTICOTROPIN RELEASING FACTOR[9-41]; MORPHINE; NALOXONE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG WITHDRAWAL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; NONHUMAN; PTOSIS; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; WET DOG SHAKES; WITHDRAWAL SYNDROME;

ANIMALS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; CORTICOTROPIN-RELEASING HORMONE; HORMONE ANTAGONISTS; INJECTIONS, INTRAVENTRICULAR; MALE; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 0032127154     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(98)00039-6     Document Type: Article

References (26)

1. AHTEE L., ATTILA L., CARLSON K., and HAIKALA H. (1989) Changes in brain monoamine metabolism during withdrawal from chronic oral self administration of morphine and in response to a morphine challege in withdrawn state.J.Pharmac.exp.Ther.249:303-310
2. BLASIG, J., HERZ, A., REINHOLD, K., and ZIELGANSBERGER, S. (1973) Development of physical dependence on morphine in respect to time and dosage and quantification of the precipitated withdrawal syndrome in rats. Psychopharmacology 33: 19-38.
3. BUCCAFUSCO, J., MARSHAL, D., and TARNER., R. (1984) A comparison of the inhibitory effects of clonidine and guamfacine on the behavioral and automatic components of morphine withdrawal in rats.Life Sci 35:1401-1407.
4. BUCKINGHAM, J., (1982) Secretion of corticotropin and its hypothalamic realising factor in response to morphine and opioid peptides. Neuroendocrinology 35:11-116.
5. BUCKINGHAM, J., and COOPER., T. (1984) Differences in hypothalamo - pituitary adrenocortical activity in the rat after acute and prolonged treatment with morphine. Neuroendocrinology 38:411-417.
6. BUCKINHAM, J., and COOPER, T. (1986) Interrelatinship of opioidergic and adrenergic mechanisms controlling the secretion of corticotrophin realising factor in the rat. Neuroendocrinology46 :199-206.
7. COLLIN, E., and CESSELLIN, F. (1991) Neurobiological mechanisms of opioid tolerance and dependence.Clin.Neuropharmacol 146: 465-488.
8. CRATTY, M., WARD, H., JHONSON, E., AZZARO, A., and BIRKLE L. (1995) Prenatal stress increases corticotropin-releasing factor (CRF) content and release in rat amygdala minces. Brain Res 675 (1-2) :297-302
9. DAVID, S., AND NESTLER J. (1995) Molecular mechanisms of drug reinforcement and addiction.Annu.Rev.Neurosci 18: 463-495
10. EISENBERG, R. (1985) Plasma corticosterone changes in response to central or peripheral administration of kappa and sigma opiate agonist.J.Pharmacol.Exp.Ther 233: 863-869
11. FREDERICKSON, R., and PINSKY (1975) Effect of cholinergic drugs and a partial cholinergic agonist on the development and expression of physical dependence of morphine rats. J. Pharmacol Exp. Ther 193: 44-49
12. FRENCH, E., BLOOM, F., RIVIER, C., GUILLEMIN., R. and ROSSIER J. (1978) Morphine or stress induced increases of plasma ß endorphin and prolactin are prevented by dexamethasone pretreatment. Soc.Neurosci. Abstr 4 : 408.
13. HOLLT, V., PREWLOCKI, R., and HERZ, A. (1978) ß endorphin-like immunoreacttivity in plasma pituitaries and hypothalamus of rats following treatment with opiates.Life Sci 23: 1057-1066.
14. IGNAR, D., and KHUN, C., (1990) Specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenocortical (HPA) axis: subchronic tolerance studies of endogenous opioid peptides.Brain Res 435:220-226
15. LIPOSITS, Z., PHELIX, C., and PAULL W. (1986)Electron microscopic analysis of tyrosine hydroxilase,dopamine B-hydroxylase and phenylethanolamine N-methyltransferase inmunoreactivity inervation of the hypothalamic paraventricular nucleus in the rat. Hystochemistry 84:105-120
16. LOVENBERG, T., CHALMERS, D., LIU, C., and DE SOUZA, B. (1995) CRF2 alpha and CRF2 beta receptor mRNAs are differentially distributed between the rat central nervous system and peripheral tissues.Endocrinology 136 (9): 4139-4142
17. MALDONADO, R., DAUGÉ, V., CALLEBERT, J., VILLETTE, J., FOURNIÉ-ZALUSKI M.C, FEGER, J., and ROQUES, P. (1989) Comparison of selective and complete inhibitors of enkephalin-degrading enzymes on morphine withdrawal syndrome . Eur. J. Pharmacol 165: 197-207.
18. MALDONADO, R., STINUS, L., GOLD, L., and KOOB, G. (1992) Role of different brain structures in the expression of the physical morphine withdrawal syndrome. J. Parmacol.Exp. Ther 261(2): 669-677.
19. MARTINEZ, J., VARGAS, M., FUENTE, T., DEL RIO GARCIA, J., and MILANÉS, M. (1990) Plasma ß- endorphin and cortisol levels in morphine tolerant rats and in naloxone induced withdrawal. Eur. J. Pharmacol 182: 117-123
20. ++ channel ligands modulate morphine effects on the Hypothalamus-pituitary adrenocortical (HPA) axis in rats .Eur. J. Pharmacol 232 :191-198.
21. PAXINOS, G., and WATSON, C. (1982) the rat brain in Stereotaxis coordinates. Academic Press, New York.
22. PECHNICK, R., GEORGE, R., and POLAND, R. (1985) Identification of multiple opioid receptors through neuroendocrine response. 1. Effects of agonists. J. Pharmacol.Exp. Ther. 232: 163-168
23. PERRIN, M., DONALDSON, C., CHEN, R., BLOUNT, A., BERGGREN, T., BILEZIKJIAN, L., SAWCHENKO, P., and VALE, W. (1995) Identification of a second corticotropin - releasing factor receptor gene an characterization of a cDNA expressed in the heart.Proc.Natl.Acad.Sci.USA 92(7):2969-2973
24. SUEMARU, S., DALMAN, M,. DARLINGTON, D., CASCIO, C., and SHINSAKO, J. (1989) Role of alpha - adrenergic mechanismis in effects of morphine on the hypothalamuo - pituitry adrenal and cardiovascular systems in the rat. Neuroendocrinology 49: 181-190
25. TUOMISTO, J., and MANISTO, P. (1985) Neurotransmitter regulation of anterior pituitary hormones.Pharmacol Rewiews 37:249-323
26. WILLIAMS, D., and THORN, B. (1984) Opiate withdrawal behavior after focal brain stimulation, Pharmacol.Biochem.Behav 21: 699-704