-
1
-
-
0023883150
-
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
-
Holt, I. J., Harding, A. E., and Morgan-Hughes, J. A. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature (Lond.), 331: 717-719, 1988.
-
(1988)
Nature (Lond.)
, vol.331
, pp. 717-719
-
-
Holt, I.J.1
Harding, A.E.2
Morgan-Hughes, J.A.3
-
2
-
-
0026624980
-
Diseases of the mitochondrial DNA
-
Wallace, D. C. Diseases of the mitochondrial DNA. Annu. Rev. Biochem., 61: 1175-1212, 1992.
-
(1992)
Annu. Rev. Biochem.
, vol.61
, pp. 1175-1212
-
-
Wallace, D.C.1
-
3
-
-
0030789988
-
Mutational spectrometry without phenotypic selection: Human mitochondrial DNA
-
Khrapko, K., Coller, H. A., Andre, P. C., Li, X-C., Foret, F., Belenky, A., Karger, B. L., and Thilly, W. G. Mutational spectrometry without phenotypic selection: human mitochondrial DNA. Nucleic Acids Res., 25: 685-693, 1997.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 685-693
-
-
Khrapko, K.1
Coller, H.A.2
Andre, P.C.3
Li, X.-C.4
Foret, F.5
Belenky, A.6
Karger, B.L.7
Thilly, W.G.8
-
4
-
-
0031443647
-
Mitochondrial mutational spectra in human cells and tissues
-
Khrapko, K., Coller, H. A., Andre, P. C., Li, X-C., Hanekamp, J. S., and Thilly, W. G. Mitochondrial mutational spectra in human cells and tissues. Proc. Natl. Acad. Sci. USA, 94: 13798-13803, 1997.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13798-13803
-
-
Khrapko, K.1
Coller, H.A.2
Andre, P.C.3
Li, X.-C.4
Hanekamp, J.S.5
Thilly, W.G.6
-
5
-
-
0032521417
-
Mutational spectra of a 100-base pair mitochondrial DNA target sequence in bronchial epithelial cells: A comparison of smoking and nonsmoking twins
-
Coller, H. A., Khrapko, K., Torres, A., Frampton, M. W., Utell, M. J., and Thilly, W. G. Mutational spectra of a 100-base pair mitochondrial DNA target sequence in bronchial epithelial cells: a comparison of smoking and nonsmoking twins. Cancer Res., 58: 1268-1277, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 1268-1277
-
-
Coller, H.A.1
Khrapko, K.2
Torres, A.3
Frampton, M.W.4
Utell, M.J.5
Thilly, W.G.6
-
6
-
-
0014801929
-
Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea. Biochem
-
Wunderlich, V., Schutt, M., Bottger, M., and Graffi, A. Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea. Biochem. J., 118: 99-109, 1970.
-
(1970)
J.
, vol.118
, pp. 99-109
-
-
Wunderlich, V.1
Schutt, M.2
Bottger, M.3
Graffi, A.4
-
7
-
-
0015255237
-
Studies on nitrosodimethylamine: Preferential methylation of mitochondrial DNA in rats and hamsters
-
Wunderlich, V., Tetzlaff, I., and Graffi, A. Studies on nitrosodimethylamine: preferential methylation of mitochondrial DNA in rats and hamsters. Chem. Biol. Interact., 4: 81-89, 1972.
-
(1972)
Chem. Biol. Interact.
, vol.4
, pp. 81-89
-
-
Wunderlich, V.1
Tetzlaff, I.2
Graffi, A.3
-
8
-
-
0019306958
-
Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA
-
Allen, J. A., and Coombs, M. M. Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA. Nature (Lond.), 287: 244-245, 1980.
-
(1980)
Nature (Lond.)
, vol.287
, pp. 244-245
-
-
Allen, J.A.1
Coombs, M.M.2
-
9
-
-
0019306621
-
Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo(a)pyrene
-
Washington DC
-
Backer, J. M., and Weinstein, I. B. Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo(a)pyrene. Science (Washington DC), 209: 297-299, 1980.
-
(1980)
Science
, vol.209
, pp. 297-299
-
-
Backer, J.M.1
Weinstein, I.B.2
-
10
-
-
0020026483
-
Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis
-
Washington DC
-
Niranjan, B. G., Bhat, N. K., and Avadhani, N. G. Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis. Science (Washington DC), 215: 73-75, 1982.
-
(1982)
Science
, vol.215
, pp. 73-75
-
-
Niranjan, B.G.1
Bhat, N.K.2
Avadhani, N.G.3
-
11
-
-
0025347102
-
Preferential binding of cisplatin to mitochondrial DNA and suppression of ATP generation in human malignant melanoma cells
-
Murata, T., Hibasami, H., Maekawa, S., Tagawa T., and Nakashima, K. Preferential binding of cisplatin to mitochondrial DNA and suppression of ATP generation in human malignant melanoma cells. Biochem. Int., 20: 949-955, 1990.
-
(1990)
Biochem. Int.
, vol.20
, pp. 949-955
-
-
Murata, T.1
Hibasami, H.2
Maekawa, S.3
Tagawa, T.4
Nakashima, K.5
-
12
-
-
0023813830
-
Resistance of HeLa cell mitochondrial DNA to mutagenesis by chemical carcinogens
-
Mita, S., Monnat, R. J., Jr., and Loeb, L. A. Resistance of HeLa cell mitochondrial DNA to mutagenesis by chemical carcinogens. Cancer Res., 48: 4578-4583, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 4578-4583
-
-
Mita, S.1
Monnat Jr., R.J.2
Loeb, L.A.3
-
13
-
-
0023390311
-
Mitochondrial mutagenesis in yeast: Mutagenic specificity of EMS and the effects of Rad9 and Rev3 gene products
-
Smoliska, U. Mitochondrial mutagenesis in yeast: mutagenic specificity of EMS and the effects of Rad9 and Rev3 gene products. Mutat. Res., 179: 167-174, 1987.
-
(1987)
Mutat. Res.
, vol.179
, pp. 167-174
-
-
Smoliska, U.1
-
14
-
-
0022971473
-
Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine
-
Goldmacher, V. S., Cuzick, R. A., Jr., and Thilly, W. G. Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. J. Biol. Chem., 261: 12462-12471, 1986.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 12462-12471
-
-
Goldmacher, V.S.1
Cuzick Jr., R.A.2
Thilly, W.G.3
-
15
-
-
0027292234
-
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair
-
Kat, A., Thilly, W. G., Fang, W. H., Longley, M. J., Li, G. M., and Modrich, P. An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair. Proc. Natl. Acad. Sci. USA, 90: 6426-6428, 1993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6426-6428
-
-
Kat, A.1
Thilly, W.G.2
Fang, W.H.3
Longley, M.J.4
Li, G.M.5
Modrich, P.6
-
16
-
-
0029069972
-
Mutations of GTBP in genetically unstable cells
-
Washington DC
-
Papadopoulous, N., Nicolaides, N. C., Liu, B., Parsons, R., Lengauer, C., Palombo, F., D'Arrigo, A., Markowitz, S., Willson, J. K. V., Kinzler, K. W., Jiricny, J., and Vogelstein, B. Mutations of GTBP in genetically unstable cells. Science (Washington DC), 268: 1915-1917, 1995.
-
(1995)
Science
, vol.268
, pp. 1915-1917
-
-
Papadopoulous, N.1
Nicolaides, N.C.2
Liu, B.3
Parsons, R.4
Lengauer, C.5
Palombo, F.6
D'Arrigo, A.7
Markowitz, S.8
Willson, J.K.V.9
Kinzler, K.W.10
Jiricny, J.11
Vogelstein, B.12
-
17
-
-
0018118326
-
Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: Possibility for a rapid human cell mutation assay
-
Skopek, T. R., Liber, H. L., Penman, B. W., and Thilly, W. G. Isolation of a human lymphoblastoid line heterozygous at the thymidine kinase locus: possibility for a rapid human cell mutation assay. Biochem. Biophys. Res. Commun., 84: 411-416, 1978.
-
(1978)
Biochem. Biophys. Res. Commun.
, vol.84
, pp. 411-416
-
-
Skopek, T.R.1
Liber, H.L.2
Penman, B.W.3
Thilly, W.G.4
-
18
-
-
0019404906
-
Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates
-
Furth, E. E., Thilly, W. G., Penman, B. W., Liber, H. L., and Rand, W. M. Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates. Anal. Biochem., 110: 1-8, 1981.
-
(1981)
Anal. Biochem.
, vol.110
, pp. 1-8
-
-
Furth, E.E.1
Thilly, W.G.2
Penman, B.W.3
Liber, H.L.4
Rand, W.M.5
-
19
-
-
0026511264
-
Mutational spectrometry: A general approach for hot-spot point mutations in selectable genes
-
Keohavong, P., and Thilly, W. G. Mutational spectrometry: a general approach for hot-spot point mutations in selectable genes. Proc. Natl. Acad. Sci. USA, 89: 4623-4627, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4623-4627
-
-
Keohavong, P.1
Thilly, W.G.2
-
20
-
-
0025957379
-
Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
-
Hovig, E., Smith-Sørensen, B., Brøgger, A., and Børresen, A. L. Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection. Mutat. Res., 262: 63-71, 1991.
-
(1991)
Mutat. Res.
, vol.262
, pp. 63-71
-
-
Hovig, E.1
Smith-Sørensen, B.2
Brøgger, A.3
Børresen, A.L.4
-
21
-
-
0028275083
-
Constant denaturant capillary electrophoresis (CDCE): A high resolution approach to mutational analysis
-
Khrapko, K., Hanekamp, J. S., Thilly, W. G., Belenkii, A., Foret, F., and Karger, B. L. Constant denaturant capillary electrophoresis (CDCE): a high resolution approach to mutational analysis. Nucleic Acids Res., 22: 364-369, 1994.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 364-369
-
-
Khrapko, K.1
Hanekamp, J.S.2
Thilly, W.G.3
Belenkii, A.4
Foret, F.5
Karger, B.L.6
-
22
-
-
0030921648
-
Fidelity and mutational spectrum of Pfu DNA polymerase on a human mitochondrial DNA sequence
-
André, P., Kim, A., Khrapko, K., and Thilly, W. G. Fidelity and mutational spectrum of Pfu DNA polymerase on a human mitochondrial DNA sequence. Genome Res., 7: 843-852, 1997.
-
(1997)
Genome Res.
, vol.7
, pp. 843-852
-
-
André, P.1
Kim, A.2
Khrapko, K.3
Thilly, W.G.4
-
23
-
-
0001430252
-
DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: Correspondence with melting theory
-
Fischer, S. G., and Lerman, L. S. DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory. Proc. Natl. Acad. Sci. USA, 80: 1579-1583, 1983.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 1579-1583
-
-
Fischer, S.G.1
Lerman, L.S.2
-
24
-
-
0013515254
-
-
(Ph.D. thesis). Cambridge, MA: Massachusetts Institute of Technology
-
Kat, A. MNNG mutational spectra in the human hprt gene (Ph.D. thesis). Cambridge, MA: Massachusetts Institute of Technology, 1992.
-
(1992)
MNNG Mutational Spectra in the Human hprt Gene
-
-
Kat, A.1
-
25
-
-
0025042740
-
Molecular analysis of complex human cell populations: Mutational spectra of MNNG and ICR-191
-
Cariello, N. F., Keohavong, P., Kat, A., and Thilly, W. G. Molecular analysis of complex human cell populations: mutational spectra of MNNG and ICR-191. Mutat. Res., 231: 165-176, 1990.
-
(1990)
Mutat. Res.
, vol.231
, pp. 165-176
-
-
Cariello, N.F.1
Keohavong, P.2
Kat, A.3
Thilly, W.G.4
-
26
-
-
0027052453
-
Mutational spectra in human B-cells. Spontaneous, oxygen and hydrogen peroxide-induced mutations at the hprt gene
-
Oller, A. R., and Thilly, W. G. Mutational spectra in human B-cells. Spontaneous, oxygen and hydrogen peroxide-induced mutations at the hprt gene. J. Mol. Biol., 228: 813-826, 1992.
-
(1992)
J. Mol. Biol.
, vol.228
, pp. 813-826
-
-
Oller, A.R.1
Thilly, W.G.2
-
27
-
-
15144344695
-
Mutagens and antimutagens
-
Novick, A. Mutagens and antimutagens. Brookhaven Symp. Biol., 8: 201-214, 1956.
-
(1956)
Brookhaven Symp. Biol.
, vol.8
, pp. 201-214
-
-
Novick, A.1
-
28
-
-
0025866810
-
Novel mutational spectrum induced by N-methyl-N′-nitro-W-nitrosoguanidine in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts
-
Yang, J. L., Hu, M. C., and Wu, C. W. Novel mutational spectrum induced by N-methyl-N′-nitro-W-nitrosoguanidine in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts. J. Mol. Biol., 221: 421-430, 1991.
-
(1991)
J. Mol. Biol.
, vol.221
, pp. 421-430
-
-
Yang, J.L.1
Hu, M.C.2
Wu, C.W.3
-
29
-
-
0024246089
-
Role of neighbouring bases and assessment of strand specificity in ethylmethanesulphonate and N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the SUP4-0 gene of Saccharomyces cerevisiae
-
Kohalmi, S. E., and Kunz, B. A. Role of neighbouring bases and assessment of strand specificity in ethylmethanesulphonate and N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the SUP4-0 gene of Saccharomyces cerevisiae. J. Mol. Biol., 204: 561-568, 1988.
-
(1988)
J. Mol. Biol.
, vol.204
, pp. 561-568
-
-
Kohalmi, S.E.1
Kunz, B.A.2
-
30
-
-
0023260248
-
Influence of neighbouring base sequence on N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the lacl gene of Escherichia coli
-
Burns, P. A., Gordon, A. J., and Glickman, B. W. Influence of neighbouring base sequence on N-methyl-N′-nitro-N-nitrosoguanidine mutagenesis in the lacl gene of Escherichia coli. J. Mol. Biol., 194: 385-390, 1987.
-
(1987)
J. Mol. Biol.
, vol.194
, pp. 385-390
-
-
Burns, P.A.1
Gordon, A.J.2
Glickman, B.W.3
-
31
-
-
0014672640
-
6-alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides
-
6-alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides. Nature (Lond.), 223: 206-207, 1969.
-
(1969)
Nature (Lond.)
, vol.223
, pp. 206-207
-
-
Loveless, A.1
-
33
-
-
0030730327
-
DNA repair of UV photoproducts and mutagenesis in human mitochondrial DNA
-
Pascucci, B., Versteegh, A., van Hoffen, A., van Zeeland, A. A., Mullenders, L. H., and Dogliotti, E. DNA repair of UV photoproducts and mutagenesis in human mitochondrial DNA. J. Mol. Biol., 273: 417-427, 1997.
-
(1997)
J. Mol. Biol.
, vol.273
, pp. 417-427
-
-
Pascucci, B.1
Versteegh, A.2
Van Hoffen, A.3
Van Zeeland, A.A.4
Mullenders, L.H.5
Dogliotti, E.6
-
34
-
-
0025909535
-
A genotypic mutation system measuring mutations in restriction recognition sequences
-
Felley-Bosco, E., Pourzand, C., Zijlstra, J., Amstad, P., and Cerutti, P. A genotypic mutation system measuring mutations in restriction recognition sequences. Nucleic Acids Res., 19: 2913-2919, 1991.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 2913-2919
-
-
Felley-Bosco, E.1
Pourzand, C.2
Zijlstra, J.3
Amstad, P.4
Cerutti, P.5
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