The role of histidine residues in the HXGH site of CTP:phosphocholine cytidylyltransferase in CTP binding and catalysis

European Journal of Biochemistry

Volumn 255, Issue 1, 1998, Pages 227-234

  Veitch, D P ^a   Gilham, D ^a   Cornell, R B ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Catalytic mechanism; CTP binding; CTP:phosphocholine cytidylyltransferase; HXGH site; Structure function

Indexed keywords

CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; CYTIDINE TRIPHOSPHATE; HISTIDINE;

ARTICLE; BINDING SITE; CATALYSIS; DENATURATION; ENZYME KINETICS; HYDROGEN BOND; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; STEADY STATE;

ANIMALS; BINDING SITES; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; COS CELLS; CYTIDINE TRIPHOSPHATE; ENZYME STABILITY; HISTIDINE; HYDROGEN BONDING; KINETICS; LIVER; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; RATS; TRANSFECTION;

EID: 0032125864     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2550227.x     Document Type: Article

References (33)