Analysis of beta-casein and its phosphoforms in human milk

Nutrition Research

Volumn 18, Issue 7, 1998, Pages 1175-1186

  Kroening, Terry A ^a   Mukerji, Pradip ^a   Hards, Robert G ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Beta casein; Human milk; Nutrition; Protein

Indexed keywords

BETA CASEIN;

ARTICLE; ARTIFICIAL MILK; BREAST MILK; CALORIMETRY; DENSITOMETRY; HUMAN; MAJOR CLINICAL STUDY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; QUANTITATIVE DIAGNOSIS;

EID: 0032125203     PISSN: 02715317     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0271-5317(98)00098-0     Document Type: Article

References (27)

1. 1. Lonnerdal B. Biochemistry and physiological function of human milk proteins. Am J Clin Nutr 1985; 42:1299-1317.
2. 2. Welsh JK, May JT. Antiinfective properties of human milk. J Pediatr 1979; 94:1-9.
3. 3. Koldovsky O, Thornburg W. Peptide hormones and hormone-like substances. In: Atkinson SA, Lonnerdal B, eds. Protein and non-protein nitrogen in human milk. Boca Raton, FL: CRC Press, 1989:53-66.
4. 4. Lonnerdal B, Whey protein in human milk. In: Atkinson SA, Lonnerdal B, eds. Protein and non-protein nitrogen in human milk. Boca Raton, FL: CRC Press, 1989:29-92.
5. 5. Hernell O, Blackberg L. Digestion and absorption of human milk lipids. In: Dulbecco R, ed. Encyclopedia of human biology. San Diego, CA: Academic Press, 1991: 47-56.
6. 6. Groves ML, Gordon WG. The major component of human casein: a protein phosphorylated at different levels. Arch Biochem Biophys 1970; 140:47-51.
7. 7. Kunz C, Lonnerdal B. Casein and casein subunits in preterm milk colostrum and mature human milk. J Ped Gastroen Nutr 1990; 10:454-461.
8. 8. Mykkanen HW, Wasserman RH. Enhanced absorption of calcium by casein phosphopeptides in rachitic and normal chicks. J Nutr 1980; 110:2141-48.
9. 9. Brantl V. Novel opoid peptides derived from human b-casein. Eur J Pharmacol 1984; 106:213-18.
10. 10. Migliori-Samour D, Jolles P. Casein, a prohormone with an immunomodulating role for the newborn. Experiential 1988; 44:188-93.
11. 11. Azuma N, Nagaune S, Ishino Y, Mori H, Kaminogawa S, Yamauchi K. DNA-synthesis stimulating peptides from human b-casein. Agric Biol Chem 1989; 53:2631-34.
12. 12. Kohmura M, Nio N, Kubo K, Minoshima Y, Munekata E, Ariyoshi, Y. Inhibition of angiotensin-converting enzyme by synthetic peptides of human b-casein. Agric Biol Chem 1989; 53:2107-14.
13. 13. Greenberg R, Groves ML, Dower HJ. Human b-casein: amino acid sequence and identification of phosphorylation sites. J Biol Chem 1984; 259:5132-38.
14. 14. Kunz C, Lonnerdal B. Human milk proteins: separation of whey proteins and their analysis by polyacrylamide gel electrophoresis, fast protein liquid chromatography (FPLC) gel filtration, and anion-exchange chromatography. Am J Clin Nutr 1989; 49:464-70.
15. 15. Kunz C, Lonnerdal B. Re-evaluation of the whey protein/ratio of human milk. Acta Paediatr 1992; 81:107-12.
16. 16. Kunz c, Lonnerdal B. Human-milk proteins: analysis of casein and casein subunits by anion-exchange chromatography, gel electrophoresis, and specific staining methods. Amer J Clin Nutr 1990; 51:37-46.
17. 17. Lonnerdal B, Forsum E. Casein content of human milk. Am J Clin Nutr 1985; 41:113-20.
18. 18. Hansson L, Bergstrom S, Hernell O, Lonnerdal B, Nilsson AK, Stromqvist M. Expression of human milk ß-casein in Escherchia coli: comparison of recombinant protein with native isoforms. Prot Exp and Purif 1993; 4:373-81.
19. 19. Sood SM, Chang P, Slattery CW. Interactions in human casein systems: self-association of fully phosphorylated human ß-casein. Arch Biochem Biophys 1985; 242:355-364.
20. 20. Sood SM, Chang P, Slattery CW. Interactions in human casein systems: self-association of nonphosphorylated human ß-casein. Arch Biochem Biophys 1988; 264:574-83.
21. 21. Greenberg R, Groves ML, Peterson RF. Amino terminal sequence and location of phosphate groups of the major human caseins. J Dairy Sci 1976; 59:1016-18.
22. 22. Donovan SM, Lonnerdal B. Development of a human milk protein standard. Acta Paediatr Scand 1989; 78:171-79.
23. 23. Davis BJ. Disc electrophoresis - II method and application to human serum proteins. Ann N Acad Sci 1964; 121:404-27.
24. 24. Kunz C, Lonnerdal B. Casein micelles and casein subunits in human milk. In: Atkinson SA, Lonnerdal B, eds. Protein and non-protein nitrogen in human milk. Boca Raton, FL: CRC Press, 1989:9-27.
25. 25. Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 1977; 83:346-56.
26. 26. Bradford M. A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72:248-57.
27. 27. Ehresmann B, Imbault p, Weil JH. Spectrophotometric determination of protein concentration in cell extracts containing tRNA's and rRNA's. Anal Biochem 1973; 54:454-63.